Could a less sedentary lifestyle help to beat osteoporosis?

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Description

The effects on osteoporosis of prolonged periods of sitting – and the potential impact of less sedentary behaviour – are being explored by researchers at the University of East Anglia.

Researchers will look at whether extended periods of sitting lead to increased bone loss, and whether breaking up sedentary behaviour has the opposite effect.    

Previous research has shown that prolonged sedentary behaviour could have an adverse effect on the hip bone mineral density of women.

 

The study is led by the University of Strathclyde and also involves Glasgow Caledonian University, the University of Birmingham and the Baker Heart and Diabetes Institute in Melbourne.

 

The team hope that their findings will help inform and shape future public health policy and physical activity guidelines aimed at improving bone health.

 

Researchers at UEA will carry out analysis on bone biomarkers that show the biochemical changes that sedentary behaviour has on bone turnover, and the various forms  of vitamin D to study whether  vitamin D deficiency contributes to the accelerated bone loss.

 

Prof Bill Fraser, from UEA’s Norwich Medical School, said: “We know that a sedentary lifestyle is not good for us, but we don’t yet know exactly how it causes bone loss and subsequent osteoporosis.

 

“This project will look at whether extended periods of sitting in a controlled laboratory setting  effects the bone metabolism of older adults. It will also look at the effects of breaking periods of sitting with standing , and whether this could be better for us.

 

Jonathan Tang, also from Norwich Medical School, said: “We are very excited at the prospect of this study. We will use state of the art technology here at UEA to perform biomarker analysis on blood samples to detect early changes in the bone building cycle to demonstrate effects on bone before a bone density scan can indicate bone thinning.”

 

Dr Alexandra Mavroeidi, a Senior Lecturer in Physical Activity for Health in Strathclyde’s School of Psychological Sciences & Health, is leading the study. She said: “We know that in extreme environments, such as total bed rest, bone loss is very high. In everyday life, long periods of immobility such as this are rare; however, sedentary lifestyles are commonplace in modern society, through transport, work and leisure.

 

“Studies have shown that self-reported sedentary behaviour throughout the day is as much as six to eight hours and this increases to eight to 10 hours in older adults. We were the first to show that this type of behaviour might have an adverse effect on women’s hip bone mineral density. We are now aiming to test this further.”

 

The study will use data and blood samples which have already been collected, but not analysed, in previous sedentary behaviour studies by the research group.

 

If the proof of concept study identifies a significant effect of sedentary behaviour on bone metabolism, promoting frequent breaks from sitting could be a possible, and simple, preventative intervention for osteoporosis in later life.

 

The research is being funded by the Royal Osteoporosis Society, previously the National Osteoporosis Society.

 

Professor Jon Tobias, Professor of Rheumatology at the University of Bristol and Chair of the Society’s Research Grants Committee, said: “The Research Grants Committee had a difficult job in selecting a small proportion of successful projects among the large number of interesting and high quality applications that we received.

 

“This project will conduct pioneering research into the impact of extended periods of sitting on bone metabolism, and the benefits of breaking up sedentary behaviour through more frequent bouts of physical activity. This will help us to learn more about the mechanisms behind osteoporosis, and give us a better understanding of the relationship between lifestyle and bone health.”

 

  

ENDS

 

EDITOR’S NOTES

 

1/ For more information or to request an interview, please contact the UEA communications office on +44 (0)1603 593496 or email communications@uea.ac.uk.

 

2/ The University of East Anglia (UEA) is a UK Top 15 university. Known for its world-leading research and outstanding student experience, it was awarded Gold in the Teaching Excellence Framework. UEA is a leading member of Norwich Research Park, one of Europe’s biggest concentrations of researchers in the fields of environment, health and plant science. www.uea.ac.uk

Period9 Jan 2019 → 12 Jan 2019

Media coverage

10

Media coverage

  • TitleFundación Española del Aparato Digesvo
    Media name/outletFEAD
    Media typeWeb
    Date12/01/19
    DescriptionThe eīects on osteoporosis of prolonged periods of siƫng – and the potenƟal impact of less sedentary behaviour – are being
    explored by researchers at UEA. Prof Bill Fraser and Jonathan Tang (both MED) quoted.
    PersonsJonathan Tang, William Fraser
  • TitleScientists to test if more exercise can help beat osteoporosis
    Degree of recognitionLocal
    Media name/outletEastern Daily Press (Circulation : 40713)
    Media typePrint
    CountryUnited Kingdom
    Date12/01/19
    DescriptionThe eīects on osteoporosis of prolonged periods of siƫng – and the potenƟal impact of less sedentary behaviour – are being
    explored by researchers at UEA. Prof Bill Fraser and Jonathan Tang (both MED) quoted.
    PersonsWilliam Fraser, Jonathan Tang
  • TitleInvestigadores estudian si el sedentarismo está relacionado con pérdida de masa ósea y osteoporosis
    Media name/outletDiario Siglo XXI
    Media typeWeb
    Date11/01/19
    DescriptionThe eīects on osteoporosis of prolonged periods of siƫng – and the potenƟal impact of less sedentary behaviour – are being
    explored by researchers at UEA. Prof Bill Fraser and Jonathan Tang (both MED) quoted.
    PersonsWilliam Fraser, Jonathan Tang
  • TitleInvestigadores estudian si el sedentarismo está relacionado con pérdida de masa ósea y osteoporosis
    Media name/outletBolsamania
    Media typeWeb
    Date11/01/19
    DescriptionThe eīects on osteoporosis of prolonged periods of siƫng – and the potenƟal impact of less sedentary behaviour – are being
    explored by researchers at UEA. Prof Bill Fraser and Jonathan Tang (both MED) quoted.
    PersonsJonathan Tang, William Fraser
  • TitleInvestigadores estudian si el sedentarismo está relacionado con pérdida de masa ósea y osteoporosis
    Media name/outletInterbusca
    Media typeWeb
    Date11/01/19
    DescriptionThe eīects on osteoporosis of prolonged periods of siƫng – and the potenƟal impact of less sedentary behaviour – are being
    explored by researchers at UEA. Prof Bill Fraser and Jonathan Tang (both MED) quoted.
    PersonsJonathan Tang, William Fraser
  • Title¿Puede un estilo de vida no sedentario ayudar a prevenir la osteoporosis?
    Media name/outletInfosalus
    Media typeWeb
    Date11/01/19
    DescriptionThe eīects on osteoporosis of prolonged periods of siƫng – and the potenƟal impact of less sedentary behaviour – are being
    explored by researchers at UEA. Prof Bill Fraser and Jonathan Tang (both MED) quoted.
    PersonsWilliam Fraser, Jonathan Tang
  • TitleNorwich scientists to test if leading a less sedentary lifestyle can help beat osteoporosis
    Media name/outletHEALTH BREAKING NEWS
    Media typeWeb
    Date11/01/19
    DescriptionThe eīects on osteoporosis of prolonged periods of siƫng – and the potenƟal impact of less sedentary behaviour – are being
    explored by researchers at UEA. Prof Bill Fraser and Jonathan Tang (both MED) quoted.
    PersonsWilliam Fraser, Jonathan Tang
  • TitleNorwich scientists to test if leading a less sedentary lifestyle can help beat osteoporosis
    Media name/outletNorwich Evening News (Online)
    Media typeWeb
    Date11/01/19
    DescriptionThe eīects on osteoporosis of prolonged periods of siƫng – and the potenƟal impact of less sedentary behaviour – are being
    explored by researchers at UEA. Prof Bill Fraser and Jonathan Tang (both MED) quoted.
    PersonsWilliam Fraser, Jonathan Tang
  • TitleNorwich scientists to test if leading a less sedentary lifestyle can help beat osteoporosis
    Media name/outletEastern Daily Press (Online)
    Media typeWeb
    Date11/01/19
    DescriptionThe eīects on osteoporosis of prolonged periods of siƫng – and the potenƟal impact of less sedentary behaviour – are being
    explored by researchers at UEA. Prof Bill Fraser and Jonathan Tang (both MED) quoted.
    PersonsWilliam Fraser, Jonathan Tang
  • TitleCould a less sedentary lifestyle help to beat osteoporosis?
    Media name/outletMedical Xpress
    Media typeWeb
    Date9/01/19
    DescriptionThe eīects on osteoporosis of prolonged periods of siƫng – and the potenƟal impact of less sedentary behaviour – are being
    explored in research led by the University of Strathclyde, and involving MED.
    PersonsWilliam Fraser, Jonathan Tang