Centre for Molecular and Structural Biochemistry

Projects

Projects per year 2002 2006 2008 2009 2010 2013 2014 2015 2018 2029

• 3 Not started
• 18 Active
• 183 Finished

Projects per year

Search results

• Active

  Spectroscopic and synthetic facilities for supramolecular and macromolecular systems

  Le Brun, N., Beekman, A., Bidula, S., Bradley, J., Butt, J., Cammidge, A., Cheesman, M., Crack, J., Delso, I., Ganesan, A., Gates, A., Hamilton, C., Sachdeva, A., Searcey, M. & Wallace, M.

  Engineering and Physical Sciences Research Council

  1/01/25 → 30/06/26

  Project: Research

• A Multiwavelength Analytical Centrifuge platform for Solute Characterisation

  Clarke, T., Akay, A., Butt, J., Crichton, P., Gates, A., Le Brun, N., Rowley, G., Swainsbury, D. & Hall, A.

  Biotechnology and Biological Sciences Research Council

  1/08/24 → 31/07/25

  Project: Research

• sRNA: Critical yet overlooked regulators of bacterial denitrification

  Rowley, G., Gates, A. & Wright, C.

  Biotechnology and Biological Sciences Research Council

  30/05/24 → 29/05/27

  Project: Research

• Engineering Biology Hub for environmental processing and recovery of metals; from contaminated land to industrial biotechnology in a circular economy

  Le Brun, N., Butt, J., Clarke, T. & MacMillan, F.

  UK Research & Innovation

  14/02/24 → 13/02/29

  Project: Research

• The fundamental properties and interactions of mitochondrial Uncoupling Proteins

  Crichton, P. & Clarke, T.

  Sygnature Discovery Limited

  1/10/23 → 30/09/27

  Project: Training

• Mestrelab Secondment Agreement

  Le Brun, N., Mueller, A. & Kemsley, K.

  1/10/23 → 30/09/28

  Project: Research

• Correlating movement, mechanism and ligand recognition in secondary active, sodium dependant membrane transporters

  MacMillan, F.

  Peak Proteins

  1/10/23 → 30/09/27

  Project: Training

• Correlating copper-15N-histidine hyperfine interactions with long range DEER distance constraints in the C-terminal domain of MamM.

  MacMillan, F.

  Royal Society of Chemistry

  1/03/23 → 31/10/25

  Project: Research

• Tuning extracellular cytochromes for enhanced metal recovery and nanoparticle formation

  Clarke, T., Butt, J. & Richardson, D.

  Biotechnology and Biological Sciences Research Council

  1/02/23 → 30/04/25

  Project: Research

• Creating and comprehending the circuitry of life: precise biomolecular design of multi-centre redox enzymes for a synthetic metabolism

  Butt, J.

  Biotechnology and Biological Sciences Research Council

  1/11/22 → 31/10/27

  Project: Research

• Biochemical and Physiological Characterisation of Salmonella ZraPSR

  Rowley, G. & Clarke, T.

  Royal Embassy of Saudi Arabia Cultural Bureau, London

  1/10/22 → 30/09/25

  Project: Training

• Iron-sulfur cluster-containing sensor regulators: mechanistic and structural studies of DNA-binding

  Le Brun, N. & Crack, J.

  Biotechnology and Biological Sciences Research Council

  1/01/22 → 31/12/24

  Project: Research

• STARVOX: Revealing effects of starvation and oxidative stress on denitrifying bacteria: a basis for novel N2O mitigation and industrial applications

  Gates, A. & Richardson, D.

  Research Council of Norway

  1/10/21 → 30/04/25

  Project: Research

• The iron-regulated control network of nutrient uptake in plants

  Le Brun, N.

  Biotechnology and Biological Sciences Research Council

  1/10/21 → 31/03/25

  Project: Research

• Synthesis and evaluation of X-ray structure inspired ubiquitin ligase inhibitors as anticancer lead compounds

  Hemmings, A., Angulo, J., Chantry, A., Hemmings, A., Stephenson, G. R. & Storr, T.

  The Big C Appeal

  1/10/20 → 31/03/25

  Project: Research

• SOLAR-Protect: Can tomato extracts protect skin from aging?

  Gavrilovic, J. & MacMillan, F.

  Persephone BIO

  1/10/20 → 30/09/24

  Project: Training

• Biomedical Vacation Scholarships Programme

  Bowater, R.

  Wellcome Trust

  1/12/19 → 30/09/25

  Project: Research

• Houbara Research and Conservation Programme

  Dolman, P., Richardson, D. & Burnside, J.

  Birdlife International

  1/10/11 → 30/09/25

  Project: Research

• Not started

  Developing, applying and industrialising methods for site specific attachment of chemical probes to monitor biological events

  MacMillan, F.

  NanoTemper

  1/10/25 → 30/09/29

  Project: Training

• Tuneable bioelectronics – Manipulation of bacterial proteins towards biodegradable, inducible, designer electronics with bespoke functionality

  Clarke, T. & Butt, J.

  Defence Science and Technology Laboratory

  30/09/25 → 29/09/29

  Project: Training

• Understanding nitrate assimilation pathways and nitrous oxide formation in plant-endosymbiotic bacteria

  Gates, A.

  The Biochemical Society

  24/06/25 → 3/08/25

  Project: Research

• Finished

  Biochemical Society Summer Vacation Studentship

  Clarke, T.

  The Biochemical Society

  14/08/23 → 24/09/23

  Project: Research

• Core Carbonate Chemistry Equipment

  Lettice, F., Bakker, D., Gates, A., Heywood, K., Kaiser, J., Landini, S., Marin, M. J., Melendi-Espina, S., Nolte, S., Robinson, C. & Todd, J.

  Engineering and Physical Sciences Research Council

  3/01/23 → 2/07/24

  Project: Research

• Determining the cellular distribution and antifungal mechanism of fluorescent cobalt-picolinamide complexes

  Lord, R. & Bidula, S.

  Royal Society of Chemistry

  1/01/23 → 30/06/24

  Project: Research

• Thermophilic Xylanases for the Sustainable Production of Nutraceuticals from Fruit Waste

  Hemmings, A.

  Royal Society

  2/11/22 → 29/02/24

  Project: Research

• Bespoke Biomolecular Wires for Novel Routes to Semi-Artificial Photosynthesis

  Butt, J. & van Wonderen, J.

  Royal Society of Chemistry

  1/09/22 → 31/08/23

  Project: Research

• Native mass spectrometry of proteins, proteins complexes, and protein cofactors at UEA

  Crack, J. & Le Brun, N.

  British Mass Spectrometry Society

  1/08/22 → 31/08/22

  Project: Research

• Synthesis and characterisation of vanadium complexes and their potential in the treatment of cancer.

  Lord, R.

  Saudi Arabia Government

  1/10/21 → 30/09/24

  Project: Training

• Better by Design: Chemically Diverse Biomolecular Wires

  Butt, J., Clarke, T., Meech, S. & Sachdeva, A.

  Leverhulme Trust

  15/03/21 → 14/12/24

  Project: Research

• Chemical and biological investigations of new vanadium compounds: determining their potential in the treatment of cancer

  Lord, R.

  Medical Research Council

  1/02/21 → 30/09/24

  Project: Fellowship

• Addressing Interdisciplinary challenges through Raman Microscopy - a new facility for UEA

  Lettice, F., Alexander, M., Askounis, A., Baker, A., Cammidge, A., Chao, Y., Fabian, L., Fielden, J., Hernaez, M., Hui, O., Kaplani, E., Khimyak, Y., Liss, P., Lord, R., Marin, M. J., Mayes, A., Melendi-Espina, S., Nolte, S., Romanov, A., Saeed, A., Sobolewski, A., Tolhurst, T. & Wright, J.

  Engineering and Physical Sciences Research Council

  6/11/20 → 31/08/22

  Project: Research

• New high resolution mass spectrometry facilities for macromolecules and metabolites at the University of East Anglia

  Le Brun, N., Butt, J., Gates, A., Hutchings, M., Le Gall, G., Searcey, M., Todd, J., Waller, Z., Wilson, P., Goodey, K. & Hinchliffe, A.

  Biotechnology and Biological Sciences Research Council

  5/11/20 → 4/04/21

  Project: Research

• HOS COVID Grant

  Le Brun, N.

  Royal Society of Chemistry

  1/06/20 → 30/11/20

  Project: Research

• NEUROtransmitter TRANSporters: from single molecules to human pathologies

  MacMillan, F.

  EU Horizon 2020

  1/02/20 → 31/07/24

  Project: Research

• Norwich Research Park Biochemical Society Seminar Series 2020

  Bowater, R. & Vardakou, M.

  The Biochemical Society

  1/01/20 → 31/07/22

  Project: Research

• Epigenetic control of nitrous oxide emission by denitrifying bacteria

  Gates, A., Richardson, D. & Waller, Z.

  Biotechnology and Biological Sciences Research Council

  1/11/19 → 30/09/24

  Project: Research

• Complete Dephosphorylation of Phytic Acid: Identification of Histidine Acid Phosphatases with Novel Phytase Activity for Use in Animal Feeds

  Hemmings, A. & Brearley, C.

  AB Vista

  1/10/19 → 31/03/24

  Project: Training

• Understanding the link between N-cycling and bacterial cytoskeleton in the Rhizobium-legume symbiosis

  Gates, A., Kelemen, G. & Miller, B.

  Processors & Growers Research Organisation

  1/10/19 → 30/09/23

  Project: Training

• Structural studies of novel ubiquitin ligase inhibitors to develop their therapeutic potential

  Chantry, A. & Hemmings, A.

  Wellcome Trust

  1/08/19 → 25/09/19

  Project: Research

• How the human iron regulator IRP 1 switches between mRNAbinding and non binding forms

  Le Brun, N.

  Wellcome Trust

  1/07/19 → 31/08/19

  Project: Research

• Biochemical links between DNA damage, inflammation and cell fate in the human lens

  Bowater, R. & Wormstone, M.

  The Biochemical Society

  17/06/19 → 11/08/19

  Project: Research

• Biohybrids for Solar Fuels: Whole-cell Photocatalysis by Non-photosynthetic Organisms.

  Butt, J., Clarke, T. & van Wonderen, J.

  Biotechnology and Biological Sciences Research Council

  1/01/19 → 31/12/21

  Project: Research

• Understanding the molecular mechanism of iron-sulfur cluster biogenesis

  Le Brun, N.

  Biotechnology and Biological Sciences Research Council

  1/01/19 → 31/12/21

  Project: Research

• Biochemical Society Seminars 2018-2019

  Bowater, R.

  The Biochemical Society

  10/09/18 → 29/02/20

  Project: Research

• Biosynthesis of nitrous oxide reductase: A complex bacterial multicopper enzyme essential for the global nitrogen cycle

  Gates, A.

  The Biochemical Society

  1/08/18 → 1/11/18

  Project: Research

• Understanding ligand recognition in a mammalian membrane transporter

  MacMillan, F.

  Biotechnology and Biological Sciences Research Council

  16/07/18 → 21/09/18

  Project: Research

• Understanding ligand recognition in a mammalian membrane transporter

  MacMillan, F.

  Wellcome Trust

  30/06/18 → 24/08/18

  Project: Research

• Using detergent-free purification methods to study the mechanism of LeuT

  MacMillan, F.

  The Biochemical Society

  25/06/18 → 19/08/18

  Project: Research

• Exploring Interprotein Electron Transfer by Light-driven Photoreduction

  Butt, J.

  The Biochemical Society

  18/06/18 → 12/08/18

  Project: Research

• Further development and refinement of ubiquitin ligase inhibitors as novel cancer therapeutics (Year 2 Follow on Funding)

  Chantry, A., Angulo, J., Hemmings, A. & Stephenson, G. R.

  James Tudor Foundation (The)

  1/06/18 → 31/12/20

  Project: Research