Centre for Molecular and Structural Biochemistry

Projects

Projects per year 2002 2006 2008 2009 2010 2013 2014 2015 2018 2027

• 22 Active
• 171 Finished

Projects per year

Search results

• Finished

  Native mass spectrometry of proteins, proteins complexes, and protein cofactors at UEA

  Crack, J. & Le Brun, N.

  British Mass Spectrometry Society

  1/08/22 → 31/08/22

  Project: Research

• Addressing Interdisciplinary challenges through Raman Microscopy - a new facility for UEA

  Lettice, F., Alexander, M., Askounis, A., Baker, A., Cammidge, A., Chao, Y., Fabian, L., Fielden, J., Hernaez, M., Hui, O., Kaplani, E., Khimyak, Y., Liss, P., Lord, R., Marin, M. J., Mayes, A., Melendi-Espina, S., Nolte, S., Romanov, A., Saeed, A., Sobolewski, A., Tolhurst, T. & Wright, J.

  Engineering and Physical Sciences Research Council

  6/11/20 → 31/08/22

  Project: Research

• New high resolution mass spectrometry facilities for macromolecules and metabolites at the University of East Anglia

  Le Brun, N., Butt, J., Gates, A., Hutchings, M., Le Gall, G., Searcey, M., Todd, J., Waller, Z., Wilson, P., Goodey, K. & Hinchliffe, A.

  Biotechnology and Biological Sciences Research Council

  5/11/20 → 4/04/21

  Project: Research

• HOS COVID Grant

  Le Brun, N.

  Royal Society of Chemistry

  1/06/20 → 30/11/20

  Project: Research

• Norwich Research Park Biochemical Society Seminar Series 2020

  Bowater, R. & Vardakou, M.

  The Biochemical Society

  1/01/20 → 31/07/22

  Project: Research

• Structural studies of novel ubiquitin ligase inhibitors to develop their therapeutic potential

  Chantry, A. & Hemmings, A.

  Wellcome Trust

  1/08/19 → 25/09/19

  Project: Research

• How the human iron regulator IRP 1 switches between mRNAbinding and non binding forms

  Le Brun, N.

  Wellcome Trust

  1/07/19 → 31/08/19

  Project: Research

• Biochemical links between DNA damage, inflammation and cell fate in the human lens

  Bowater, R. & Wormstone, M.

  The Biochemical Society

  17/06/19 → 11/08/19

  Project: Research

• Biohybrids for Solar Fuels: Whole-cell Photocatalysis by Non-photosynthetic Organisms.

  Butt, J., Clarke, T. & Van Wonderen, J.

  Biotechnology and Biological Sciences Research Council

  1/01/19 → 31/12/21

  Project: Research

• Understanding the molecular mechanism of iron-sulfur cluster biogenesis

  Le Brun, N.

  Biotechnology and Biological Sciences Research Council

  1/01/19 → 31/12/21

  Project: Research

• Biochemical Society Seminars 2018-2019

  Bowater, R.

  The Biochemical Society

  10/09/18 → 29/02/20

  Project: Research

• Biosynthesis of nitrous oxide reductase: A complex bacterial multicopper enzyme essential for the global nitrogen cycle

  Gates, A.

  The Biochemical Society

  1/08/18 → 1/11/18

  Project: Research

• Understanding ligand recognition in a mammalian membrane transporter

  MacMillan, F.

  Biotechnology and Biological Sciences Research Council

  16/07/18 → 21/09/18

  Project: Research

• Understanding ligand recognition in a mammalian membrane transporter

  MacMillan, F.

  Wellcome Trust

  30/06/18 → 24/08/18

  Project: Research

• Using detergent-free purification methods to study the mechanism of LeuT

  MacMillan, F.

  The Biochemical Society

  25/06/18 → 19/08/18

  Project: Research

• Exploring Interprotein Electron Transfer by Light-driven Photoreduction

  Butt, J.

  The Biochemical Society

  18/06/18 → 12/08/18

  Project: Research

• Further development and refinement of ubiquitin ligase inhibitors as novel cancer therapeutics (Year 2 Follow on Funding)

  Chantry, A., Angulo, J., Hemmings, A. & Stephenson, G. R.

  James Tudor Foundation (The)

  1/06/18 → 31/12/20

  Project: Research

• A high sensitivity elemental mass spectrometry facility to support metallo-biology research on the Norwich Research Park

  Le Brun, N., Balk, J., Brearley, C., Butt, J., Crombie, A., Hamilton, C., Hemmings, A., Murrell, C., Rix, L., Rix, L., Chilvers, G. & Hinchliffe, A.

  Biotechnology and Biological Sciences Research Council

  1/05/18 → 30/04/19

  Project: Research

• Revealing the microbial process of iron-driven anaerobic ammonium oxidation

  Bond, P., Richardson, D. & Hu, S.

  Australian Research Council

  1/04/18 → 31/03/21

  Project: Research

• Structure and mechanism of the iron-sulfur cluster biogenesis regulator IscR

  Le Brun, N.

  Royal Society

  16/03/18 → 15/09/22

  Project: Research

• Phenotypic diversification in denitrification: mechanisms, prevalence and implications.

  Gates, A. & Richardson, D.

  Research Council of Norway

  1/02/18 → 30/09/21

  Project: Research

• The assembly and folding pathway of porin cytochrome complexes in the bacterial outer membrane

  Clarke, T., Butt, J., Richardson, D. & Edwards, M.

  Biotechnology and Biological Sciences Research Council

  1/01/18 → 30/09/21

  Project: Research

• REMineralisation of organic carbon by marine bActerIoplanktoN (REMAIN) - reducing the known unknown

  Robinson, C., Buitenhuis, E., Garcia-Martin, E. E., Munoz-Herranz, M. P., Todd, J., Watmough, N., Macdonald, A. & Utting, R.

  Natural Environment Research Council

  1/12/17 → 30/11/22

  Project: Research

• Mechanistic studies of mitochondrial ferritin, a key player in iron mediated oxidative stress response and cellular iron metabolism

  Le Brun, N., Bradley, J., Hemmings, A. & Moore, G.

  Biotechnology and Biological Sciences Research Council

  1/10/17 → 30/09/20

  Project: Research

• The biodiversity of organic phosphate (phytate) cycling in soils?

  Brearley, C., Hemmings, A. & Todd, J.

  AB Vista

  1/10/17 → 31/03/21

  Project: Training

• Astra Zeneca Collaboration

  Chantry, A., Bulman Page, P., Hemmings, A. & Stephenson, G. R.

  AstraZeneca

  1/08/17 → 31/10/18

  Project: Research

• Making ends meet: novel forms of bacterial DNA ligases from Paracoccus denitrificans

  Gates, A. & Bowater, R.

  The Biochemical Society

  3/07/17 → 27/08/17

  Project: Research

• Catalytic Protein Film Voltammetry of an Annamox Cytochrome

  Butt, J.

  The Biochemical Society

  19/06/17 → 28/07/17

  Project: Research

• Structural and mechanistic insights into NO sensing by iron-sulfur cluster regulators

  Le Brun, N. & Crack, J.

  Biotechnology and Biological Sciences Research Council

  30/05/17 → 29/09/20

  Project: Research

• A multidisciplinary study of DMSP production and lysis - from enzymes to organisms to process modelling.

  Todd, J., Airs, R., Beale, R., Hopkins, F., Le Brun, N., Malin, G., Polimene, L., Pratscher, J., Tarran, G. & Green, R.

  Natural Environment Research Council

  1/05/17 → 30/04/22

  Project: Research

• A novel generic method for prediction of spectral line shapes from Molecular Dynamics modelling: Application to EPR

  Oganesyan, V.

  Engineering and Physical Sciences Research Council

  1/01/17 → 31/12/18

  Project: Research

• NRP Biochemical Society Seminar Series 2016-17

  Bowater, R.

  The Biochemical Society

  1/10/16 → 31/12/17

  Project: Research

• Intern supervision and expert advice services

  Bowater, R. & Bowater, L.

  Challs International Ltd

  13/07/16 → 31/01/17

  Project: Consultancy

• Digital Image Documentation of Protein Crystallization Experiments

  Hemmings, A.

  John & Pamela Salter Charitable Trust (The)

  1/04/16 → 30/11/18

  Project: Research

• Biochemical Society Sponsored Seminar Series

  Bowater, R.

  The Biochemical Society

  1/01/16 → 30/09/16

  Project: Research

• Functional characterisation of Iron Regulator Sensor (IRS) proteins in plants

  Balk, J. & Le Brun, N.

  Biotechnology and Biological Sciences Research Council

  1/01/16 → 31/12/18

  Project: Research

• Biochemical Society to develop an introductory MOOC on Biochemistry for 16-19 year olds

  Bowater, R., Gillespie, H. & MacMillan, F.

  The Biochemical Society

  1/01/16 → 31/08/16

  Project: Other

• BrIdging Structural BiOlogy with Biological SyNthesis and Self Assembly to Reveal Key Processes in Living Systems

  Bowater, R., Butt, J., Clarke, T., Gates, A., Hamilton, C., Hutchings, M., Le Brun, N., Rowley, G., Searcey, M. & Waller, Z.

  EU Horizon 2020

  1/01/16 → 31/12/18

  Project: Research

• Mapping the Catalytic Landscape of a Novel Phytase

  Hemmings, A. & Brearley, C.

  AB Vista

  30/09/15 → 29/06/19

  Project: Research

• Mapping the Catalytic Landscape of a Novel Phytase

  Hemmings, A. & Brearley, C.

  Biotechnology and Biological Sciences Research Council

  30/09/15 → 29/06/19

  Project: Research

• Biohybrids for Solar-Electrosynthesis Inspired by 'Rock-Breathing' Bacteria

  Butt, J.

  Royal Society

  1/09/15 → 30/09/16

  Project: Fellowship

• Metals in Biology PoC

  Le Brun, N., Cheesman, M. & Todd, J.

  Biotechnology and Biological Sciences Research Council

  1/08/15 → 31/05/16

  Project: Research

• NRP-UEA iGEM 2015: Engineering novel carbohydrates for health and industry

  Bowater, R.

  International Genetically Engineered Machine Foundation (iGEM)

  15/06/15 → 21/08/15

  Project: Research

• Fraser Macmillan Biochemical Society Summer Bursary

  MacMillan, F.

  The Biochemical Society

  8/06/15 → 8/06/15

  Project: Research

• Towards a molecular description of the conformational change in actin binding domain required to bind F-actin - Jenny Hall

  MacMillan, F.

  Wellcome Trust

  8/06/15 → 2/08/15

  Project: Research

• Battelle SFA (2015)

  Richardson, D., Butt, J., Clarke, T. & Beckwith, C.

  Battelle Science & Technology International

  1/05/15 → 31/12/15

  Project: Research

• Newton Fellowship

  Le Brun, N.

  Royal Society

  23/03/15 → 22/03/17

  Project: Fellowship

• Investigating the role of cations in altering DNA conformation and gene expression in bacteria

  Gates, A. & Waller, Z.

  Royal Society

  16/03/15 → 15/03/16

  Project: Research

• BBSRC Business Interaction Vouchers

  Le Brun, N.

  Biotechnology and Biological Sciences Research Council

  1/02/15 → 31/07/15

  Project: Research

• Characterisation of electron transport in a bracterial nano-wire through high performance computing and experimentation

  Butt, J., Clarke, T., Meech, S. & Watmough, N.

  Engineering and Physical Sciences Research Council

  26/01/15 → 30/11/18

  Project: Research