Projects per year
Organisation profile
Research under the Chemistry of Life Processes theme applies state of the art technologies in areas such as:
- biophysical chemistry,
- theoretical simulation,
- protein engineering and genetic programming to understand a wide range of biological processes and to
- develop synthetic biology approaches towards novel applications of biological systems.
Systems under study include:
- the roles of metals in life,
- nitrogen cycle enzymes,
- multiheme cytochromes,
- membrane transporters,
- protein-protein interactions and
- unnatural amino acids.
Collaborations and top research areas from the last five years
Profiles
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Tharin Blumenschein
- School of Chemistry, Pharmacy and Pharmacology - Associate Professor in Biomolecular NMR Spectroscopy
- Centre for Molecular and Structural Biochemistry - Member
- Chemistry of Life Processes - Member
Person: Research Group Member, Research Centre Member, Academic, Teaching & Research
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Julea Butt
- School of Biological Sciences - Professor of Biophysical Chemistry
- Centre for Molecular and Structural Biochemistry - Member
- Centre for Photonics and Quantum Science - Member
- Chemistry of Life Processes - Member
- Chemistry of Light and Energy - Member
- Energy Materials Laboratory - Member
- Molecular Microbiology - Member
Person: Research Group Member, Research Centre Member, Academic, Teaching & Research
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Myles Cheesman
- School of Chemistry, Pharmacy and Pharmacology - Lecturer
- Centre for Molecular and Structural Biochemistry - Member
- Chemistry of Life Processes - Member
- Chemistry of Light and Energy - Member
Person: Research Group Member, Research Centre Member, Academic, Teaching & Research
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A Multiwavelength Analytical Centrifuge platform for Solute Characterisation
Clarke, T., Akay, A., Butt, J., Crichton, P., Gates, A., Le Brun, N., Rowley, G., Swainsbury, D. & Hall, A.
Biotechnology and Biological Sciences Research Council
1/08/24 → 31/07/25
Project: Research
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Synthesis of caged porphyrin-phthalocyanine assemblies
Royal Embassy of Saudi Arabia Cultural Bureau, London
1/12/23 → 30/11/24
Project: Training
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A redox switch allows binding of ferrous and ferric ions in the cyanobacterial iron binding protein FutA from Prochlorococcus
Bolton, R., Machelett, M. M., Stubbs, J., Axford, D., Caramello, N., Catapano, L., Malý, M., Rodrigues, M. J., Cordery, C., Tizzard, G. J., MacMillan, F., Engilberge, S., von Stetten, D., Tosha, T., Sugimoto, H., Worrall, J. A. R., Webb, J. S., Zubkov, M., Coles, S., Mathieu, E., & 9 others , 19 Mar 2024, In: Proceedings of the National Academy of Sciences of the United States of America. 121, 12, e2308478121.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Downloads (Pure) -
Binding of a single nitric oxide molecule is sufficient to disrupt DNA binding of the nitrosative stress regulator NsrR
Crack, J. C. & Le Brun, N., 7 Dec 2024, In: Chemical Science. 15, 45, p. 18920-18932 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Binding of IscU and TusA to different but competing sites of IscS influences the activity of IscS and directs sulfur to the respective biomolecular synthesis pathway
Olivieri, P., Klabes, M., Crack, J. C., Lehmann, A., Bennett, S. P., Le Brun, N. E. & Leimkuhler, S., 6 Aug 2024, In: Microbiology Spectrum. 12, 8, e00949-24.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Downloads (Pure)
Datasets
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Nash et al Datasets for 'Tethered heme domains in a triheme cytochrome allow for increased electron transport distances.'
Clarke, T. (Creator), Nash, B. (Creator), Edwards, M. J. (Creator), Svistunenko, D. A. (Creator), Fernandez, T. (Creator), Morgado, L. (Creator), van Wonderen, J. (Creator), Butt, J. (Creator) & Salgueiro, C. A. (Creator), University of East Anglia, 19 Feb 2024
Dataset
File -
Genetic Code Expansion in Shewanella oneidensis MR-1 allows Site-Specific Incorporation of Bioorthogonal Functional Groups into a c-type Cytochrome: Data sets for this study
Lockwood, C. (Creator), Nash, B. (Creator), Whiting, K. (Creator), Connolly, A. (Creator), Sutton-Cook, A. (Creator), Crook, A. (Creator), Edwards, M. J. (Creator), Clarke, T. (Supervisor), Sachdeva, A. (Supervisor) & Butt, J. (Supervisor), American Chemical Society, 2024
Dataset
File -
Bespoke biomolecular wires for transmembrane electron transfer: Data sets
Piper, S. (Creator), Edwards, M. (Creator), van Wonderen, J. (Contributor), Casadevall, C. (Creator), Martel, A. (Contributor), Jeuken, L. J. C. (Contributor), Reisner, E. (Contributor), Clarke, T. (Contributor) & Butt, J. (Contributor), Frontiers Media S.A., 27 Jul 2021
https://doi.ill.fr/10.5291/ILL-DATA.8-03-986
Dataset
File
Activities
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Molecules (Journal)
Tharin Blumenschein (Peer reviewer)
15 Nov 2024Activity: Editorial work › Publication peer-review
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School of Chemistry, Pharmacy and Pharmacology Research Day
Maria J. Marin (Invited speaker)
13 Sep 2024Activity: Participating in or organising an event › Invited talk
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Symposium Organiser and Chair - Nanobiophotonics - nanoscience to address biological challenges at 18th International Congress on Photobiology
Maria J. Marin (Session organiser)
27 Aug 2024Activity: Participating in or organising an event › Other
Press/Media
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Chemistry in Pictures: Chem brûlée
Rianne Lord
26/05/22
1 Media contribution
Press/Media: Media Coverage or Contribution