Molecular and Tissue Pharmacology

Projects

Projects per year 2003 2009 2011 2019 2026

• 1 Not started
• 5 Active
• 51 Finished

Projects per year

Search results

• Active

  New cell membrane-penetrating Nrf2 peptides and their therapeutic effects on lupus nephritis

  Searcey, M. & O'Connell, M.

  Royal Society

  30/03/21 → 29/03/24

  Project: Research

• Molecular mechanisms coupling matrix rigidity to DNA damage in smooth muscle.

  Warren, D.

  Biotechnology and Biological Sciences Research Council

  9/03/20 → 5/04/23

  Project: Research

• Anti tumour agents from natural products - new approaches to targeting ultra potent analogues of the duocarmycins.

  Searcey, M., O'Connell, M. & Cominetti, M.

  Engineering and Physical Sciences Research Council

  1/01/20 → 31/08/23

  Project: Research

• The role of P2X receptors in immune-sensory neuron interplay

  Fountain, S. & Stokes, L.

  AstraZeneca

  1/10/19 → 30/09/23

  Project: Training

• Donation for Glaucoma research

  Sanderson, J.

  Norfolk & Norwich University Hospitals NHS Foundation Trust

  1/10/09 → 30/09/23

  Project: Research

• Not started

  Control transcription factors with protein-protein and protein-DNA interactions

  Beekman, A. & O'Connell, M.

  Worldwide Cancer Research

  1/06/23 → 31/05/26

  Project: Research

• Finished

  Cancer medicines: From the laboratory to the patient

  Hobson, E. & O'Connell, M.

  British Pharmacological Society

  3/01/23 → 28/02/23

  Project: Research

• NNUH Glaucoma Research Fund - Studentship Stipend - Thomas Carr

  Sanderson, J.

  Norfolk & Norwich University Hospitals NHS Foundation Trust

  1/10/22 → 31/12/22

  Project: Research

• Does increased matrix stiffness within the tumour microenvironment switch endothelial cells into a pro-angiogenic / pro-tumourigenic state?

  Warren, D.

  The Big C Appeal

  4/07/22 → 28/08/22

  Project: Training

• Open forum to discuss race and race relations in Science

  Mueller, A., Norton, R. & O'Connell, M.

  British Society for Immunology

  1/10/21 → 31/10/21

  Project: Research

• Addressing Interdisciplinary challenges through Raman Microscopy - a new facility for UEA

  Lettice, F., Alexander, M., Askounis, A., Baker, A., Cammidge, A., Chao, Y., Fabian, L., Fielden, J., Hernaez, M., Hui, O., Kaplani, E., Khimyak, Y., Liss, P., Lord, R., Marin, M. J., Mayes, A., Melendi-Espina, S., Nolte, S., Romanov, A., Saeed, A., Sobolewski, A., Tolhurst, T. & Wright, J.

  Engineering and Physical Sciences Research Council

  6/11/20 → 31/08/22

  Project: Research

• To understand mechanisms regulating smooth muscle cell stiffness in people with diabetes

  Warren, D.

  Diabetes UK (The British Diabetic Association)

  3/02/20 → 2/08/21

  Project: Research

• Releasing a new undergraduate resource for pharmacology teaching: ReceptorCards

  Stokes, L. & Norton, R.

  British Pharmacological Society

  1/11/19 → 31/10/20

  Project: Research

• Additively printed bio-trigged comfort agent-eluting contact lenses

  Qi, S., Alexander, M. & Sanderson, J.

  CooperVision

  16/09/19 → 15/09/21

  Project: Research

• Determining the effect of eosinophils on the growth and apoptosis of lung adenocarinoma A549 cells.

  Sobolewski, A.

  Wellcome Trust

  29/07/19 → 6/09/19

  Project: Research

• Big C Studentship

  Mueller, A.

  The Big C Appeal

  17/06/19 → 12/07/19

  Project: Research

• Mechanisms of Neurodegeneration in Glaucoma.

  Sanderson, J.

  Norfolk & Norwich University Hospitals NHS Foundation Trust

  1/04/19 → 30/06/22

  Project: Training

• Building an ex-vivo model for evaluation of effectiveness of drug-eluting contact lenses for treating glaucoma

  Qi, S. & Sanderson, J.

  Royal Society

  5/11/18 → 4/11/21

  Project: Research

• The impact of matrix stiffness on smooth muscle cell contractile function

  Warren, D. & Fountain, S.

  British Heart Foundation

  1/10/18 → 30/03/22

  Project: Training

• Does enhanced smooth muscle cell contraction increase local matrix stiffness and promote smooth muscle cell proliferation?

  Warren, D. & Fountain, S.

  British Heart Foundation

  1/10/17 → 31/12/20

  Project: Training

• Development of Receptor Cards for undergraduate pharmacology teaching.

  Stokes, L.

  British Pharmacological Society

  1/08/17 → 31/07/18

  Project: Training

• Drug discovery for novel P2X4 ion channel modulators derived from spider venoms.

  Stokes, L.

  Royal Society

  1/04/17 → 31/03/18

  Project: Research

• Extra budget for iCASE studentship in "Establishing optimal dietary flavonoid intake through in vitro characterisation of metabolite activity"

  O'Connell, M.

  Biotechnology and Biological Sciences Research Council

  1/10/16 → 31/03/21

  Project: Training

• Enhancing microbial killing through the novel action of Panax ginseng derivatives on P2X7.

  Stokes, L.

  Biotechnology and Biological Sciences Research Council

  26/09/16 → 25/09/19

  Project: Research

• Inhibition of the Pro-Survival Protein Mcl-1 for the Treatment of Melanoma

  Howell, L. & O'Connell, M.

  British Skin Foundation (The)

  1/08/16 → 31/12/16

  Project: Research

• Are metabolites of natural products responsible for the vascular health benefits of fruit and vegetable consumption?

  O'Connell, M., Cassidy, A. & Searcey, M.

  Biotechnology and Biological Sciences Research Council

  1/05/16 → 31/10/19

  Project: Research

• Taiwan-Norwich: Development of an integrated platform for the study of mechanisms underlying ageing

  Carding, S., Gavrilovic, J., Mccormick, P., Minihane, A., O'Connell, M. & Sanderson, J.

  Biotechnology and Biological Sciences Research Council

  11/09/14 → 31/10/16

  Project: Research

• Investigating the Inhibition of the p53-MDMX Protein-Protein Interaction for the Treatment of Melanoma

  Searcey, M., Howell, L. & O'Connell, M.

  British Skin Foundation (The)

  1/09/14 → 31/08/15

  Project: Research

• Humane Research Trust Laboratory

  Wormstone, M., Sanderson, J., Evans-Gowing, R. & Russell, S.

  Humane Research Trust (The)

  1/01/14 → 31/12/16

  Project: Research

• BBSRC DRINC Travel Fund Award

  Kay, C. & O'Connell, M.

  Biotechnology and Biological Sciences Research Council

  1/03/13 → 30/06/13

  Project: Research

• An in vitro model for assessment of drug toxicity in the human retina - AstraZeneca Studentship

  Sanderson, J.

  AstraZeneca

  1/10/12 → 30/09/15

  Project: Training

• Targeting Nrf2 in inflammation: development of in vitro assays to assess protein-protein interactions between Nrf2 and Keap1

  O'Connell, M. & Searcey, M.

  The Biochemical Society

  1/03/12 → 28/02/13

  Project: Research

• Delivery of ultrapotent cytoxins in the treatment of lung cancer (Studentship - Michael Stephenson)

  Searcey, M. & O'Connell, M.

  Novartis UK Ltd

  1/10/11 → 30/09/14

  Project: Training

• Donation for Glaucoma Research (Edith Murphy Foundation)

  Sanderson, J.

  Edith Murphy Foundation

  1/10/11 → 30/09/13

  Project: Research

• Donation for Glaucoma Research

  Sanderson, J.

  Norfolk & Norwich University Health Care Trust Charitable Fund

  1/05/11 → 31/07/13

  Project: Research

• Metal-based anti-Cancer agents

  Redshaw, C. & Mueller, A.

  Whitelaw Frater Cancer Trust

  1/04/11 → 31/08/12

  Project: Research

• The collective bioactivity of dietary flavonoids: importance of specific structural characteristics for cardiovascular benefits

  Kay, C., Cassidy, A. & O'Connell, M.

  Biotechnology and Biological Sciences Research Council

  28/03/11 → 27/03/14

  Project: Research

• Non-platinum based metal complexes as anti cancer agents

  Redshaw, C., Bulman Page, P. & Mueller, A.

  The Big C Appeal

  4/10/10 → 3/10/11

  Project: Research

• Regulation of the transcription factor Nrf2 by protein kinase C alpha

  O'Connell, M.

  The Biochemical Society

  7/06/10 → 30/07/10

  Project: Research

• UEA / Pfizer Ocular Project

  Barker, S. & Sanderson, J.

  Pfizer

  9/11/09 → 31/12/10

  Project: Research

• Investigation of Calcium Homeostasis in Human Retinal Ganglion Cells

  Sanderson, J. & Rhodes, J.

  Humane Research Trust (The)

  1/10/09 → 30/09/11

  Project: Research

• Donations for Glaucoma research

  Sanderson, J.

  Norfolk & Norwich University Health Care Trust Charitable Fund

  1/10/09 → 30/09/13

  Project: Research

• FSF Funding for Glaucoma Research

  Sanderson, J. & Broadway (N & N), D.

  National Institute for Health and Care Research

  1/10/09 → 30/09/10

  Project: Research

• Boracalixarenes

  Redshaw, C., Matthews, S. & Mueller, A.

  Whitelaw Frater Cancer Trust

  1/10/09 → 30/09/10

  Project: Research

• Investigation into gene transfection with functionalised multicalixarenes

  Mueller, A.

  Nuffield Foundation (The)

  8/06/09 → 27/07/09

  Project: Research

• Effects on vitamin D on pro-inflammatory responsess in human airway epithelial cells

  O'Connell, M.

  Nutricia Research Foundation

  1/04/09 → 31/12/10

  Project: Research

• To establish a pre-clinical screening method to identify cataractogenic potential of novel compounds

  Wormstone, M. & Sanderson, J.

  Biologie Servier

  1/01/09 → 31/03/12

  Project: Research

• Novel transfection vectors for delivery of SiRNA

  Matthews, S. & Mueller, A.

  Association for International Cancer Research

  1/10/08 → 30/11/11

  Project: Research

• Glaucoma studentship

  Sanderson, J.

  Edith Murphy Foundation

  1/10/08 → 30/09/11

  Project: Research

• In vitro evaluation of the effect of EVT101 on the lens

  Wormstone, M. & Sanderson, J.

  Evotec

  1/06/08 → 31/05/10

  Project: Research