Projects per year
Organisation profile
Attaining world-leading research and educational standards
Our aim is, (1) to conduct world-leading nutrition research which spans from fundamental mechanistic studies to large pragmatic trials in healthy participants and ‘at risk’ groups, and (2) to effectively educate our MBBS, PA and PGR students in the understanding of nutrition in health and disease-risk reduction. Through both mechanisms we help deliver the government Ageing Grand Challenge goal of increasing healthy life expectancy by five years by 2035.
We investigate the impact of key dietary components and dietary patterns on health and risk of major age-related chronic diseases, in particular cardio-metabolic health, musculoskeletal health, cognitive health and dementia, micronutrient deficiency conditions and prostate cancer. Our research uses a combination of cell and animal models, prospective epidemiology (EPIC Norfolk and Potsdam, Twins UK, UK Biobank etc.) intervention trials in healthy and patient groups, food bioactive absorption and metabolism studies, genomics and lipidomics. Research interests in eating behaviour and its determinants, is now based in Norfolk Institute of Health Ageing (NIHA, www.healthyageingnorfolk.com ) launched in August 2020, of which Prof Anne Marie Minihane is Director.
Main Research areas of interest
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Flavonoids and their metabolites, and cardio-metabolic and cognitive health
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n-3 fatty acids, metabolism and cognition
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Gut-liver-brain axis and the role of the microbiota
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Micronutrient status, health and malnutrition e.g. iron and vitamin D
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Dietary fibres and glucose metabolism
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Nutrient-gene interactions and personalised nutrition
Collaborations and top research areas from the last five years
Profiles
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Yongping Bao
- Norwich Medical School - Professor of Nutritional Biochemistry
- Metabolic Health - Member
- Nutrition and Preventive Medicine - Member
- Cancer Studies - Member
Person: Research Group Member, Research Centre Member, Academic, Teaching & Research
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Ian Clark
- School of Biological Sciences - Professor of Musculoskeletal Biology
- Musculoskeletal Medicine - Member
- Nutrition and Preventive Medicine - Member
- HealthUEA - Academic Chair
Person: Research Group Member, Academic, Teaching & Research
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Peter Curtis
- Norwich Medical School - Associate Professor
- Norwich Institute for Healthy Aging - Member
- Lifespan Health - Member
- Nutrition and Preventive Medicine - Member
Person: Research Group Member, Research Centre Member, Academic, Teaching & Research
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Pathways to precision: preparing systems for MLTC management (P2P-MLTC)
Macgregor, A., Davies, C. & Howard Wilsher, S.
NHS Norfolk & Waveney Integrated Care Board
30/10/24 → 31/03/25
Project: Research
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Changing the trajectories of mental health difficulties in Norfolk and Suffolk: a research-priority-setting project with patients, the public, clinicians, policymakers and other stakeholders—study protocol
Oduola, S., Morgan, C., Das-Munshi, J., Broomfield, N., Parretti, H., Sanderson, K., Notley, C., Zile, A., Morrissey, S., Khadjesari, Z. & Holmes, J., Jan 2025, In: BMJ Open. 15, 1, e093980.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Downloads (Pure) -
microRNA-324 mediates bone homeostasis and the regulation of osteoblast and osteoclast differentiation and activity
Hayman, D. J., Johnson de Sousa Brito, F., Lin, H., Prior, A., Charlesworth, G., Hao, Y., Pearson, R. D., Soul, J., Clark, I. M., Piróg, K. A., Barter, M. J., van't Hof, R. J. & Young, D. A., Jan 2025, In: Bone. 190, 117273.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Downloads (Pure) -
(Poly)phenol-rich grape and blueberry extract prevents LPS-induced disruption of the blood-brain barrier through the modulation of the gut microbiota-derived uremic toxins
Connell, E., Le Gall, G., McArthur, S., Lang, L., Breeze, B., Pontifex, M. G., Sami, S., Pourtau, L., Gaudout, D., Müller, M. & Vauzour, D., Nov 2024, In: Neurochemistry International. 180, 105878.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Downloads (Pure)
Prizes
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Fahrenheit Placement Prize for Excellence
Davidson, Rosemary (Recipient), 2004
Prize: Prize (including medals and awards)
Activities
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Innovation and Technology Commission (ITC) of the Hong Kong Special Administrative Region Government (HKSARG) (External organisation)
David Vauzour (Member)
4 Dec 2024Activity: Membership › Peer review panel
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How do dietary factors influence musculoskeletal and cardiovascular health (Keynote lecture)
Ailsa Welch (Speaker)
22 Nov 2024Activity: Participating in or organising an event › Participation in external training
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Suffolk Food summit
Sarah Hanson (Speaker)
12 Nov 2024Activity: Participating in or organising an event › Invited talk
Press/Media
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Food poverty in Norfolk: ‘Children have bowed legs’: hunger worse than ever, says Norwich school
21/12/23
1 Media contribution
Press/Media: Media Coverage or Contribution
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Expert reaction to vitamin D supplements and bone fractures in children in Mongolia
1/12/23
1 Media contribution
Press/Media: Media Coverage or Contribution
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BBC story on lockdown experiences (July 2023)
7/07/23
1 Media contribution
Press/Media: Media Coverage or Contribution