Projects per year
Organisation profile
Organisation profile
Attaining world-leading research and educational standards
Our aim is, (1) to conduct world-leading nutrition research which spans from fundamental mechanistic studies to large pragmatic trials in healthy participants and ‘at risk’ groups, and (2) to effectively educate our MBBS, PA and PGR students in the understanding of nutrition in health and disease-risk reduction. Through both mechanisms we help deliver the government Ageing Grand Challenge goal of increasing healthy life expectancy by five years by 2035.
We investigate the impact of key dietary components and dietary patterns on health and risk of major age-related chronic diseases, in particular cardio-metabolic health, musculoskeletal health, cognitive health and dementia, micronutrient deficiency conditions and prostate cancer. Our research uses a combination of cell and animal models, prospective epidemiology (EPIC Norfolk and Potsdam, Twins UK, UK Biobank etc.) intervention trials in healthy and patient groups, food bioactive absorption and metabolism studies, genomics and lipidomics. Research interests in eating behaviour and its determinants, is now based in Norfolk Institute of Health Ageing (NIHA, www.healthyageingnorfolk.com ) launched in August 2020, of which Prof Anne Marie Minihane is Director.
Main Research areas of interest
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Flavonoids and their metabolites, and cardio-metabolic and cognitive health
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n-3 fatty acids, metabolism and cognition
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Gut-liver-brain axis and the role of the microbiota
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Micronutrient status, health and malnutrition e.g. iron and vitamin D
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Dietary fibres and glucose metabolism
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Nutrient-gene interactions and personalised nutrition
Network
Profiles
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Ian Clark
- School of Biological Sciences - Professor of Musculoskeletal Biology
- Musculoskeletal Medicine - Member
- Nutrition and Preventive Medicine - Member
Person: Research Group Member, Academic, Teaching & Research
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Peter Curtis
- Norwich Medical School - Associate Professor
- Norwich Institute for Healthy Aging - Member
- Nutrition and Preventive Medicine - Member
Person: Research Group Member, Research Centre Member, Academic, Teaching & Research
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Rosemary Davidson
- Norwich Medical School - Lecturer in Nutrition and Biomedicine
- Norwich Institute for Healthy Aging - Member
- Nutrition and Preventive Medicine - Member
Person: Research Group Member, Research Centre Member, Academic, Teaching & Research
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The role of microRNA-455 in bone metabolism
Action Arthritis (Norwich Hip Trust)
1/01/23 → 30/06/23
Project: Research
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Investigating the gut brain connections in early cognitive decline and dementia
1/12/22 → 31/05/23
Project: Research
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3’ untranslated region structural elements in CYP24A1 are associated with infantile hypercalcaemia type 1
Ball, N., Duncan, S., Zhang, Y., Payet, R., Piec, I., Whittle, E., Tang, J. C. Y., Schoenmakers, I., Lopez, B., Chipchase, A., Kumar, A., Perry, L., Maxwell, H., Ding, Y., Fraser, W. D. & Green, D., Mar 2023, In: Journal of Bone and Mineral Research. 38, 3, p. 414-426 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Cognitive impairment in the immune-mediated inflammatory diseases compared with age-matched controls: systematic review and meta-regression
Gwinnutt, J. M., Toyoda, T., Barraclough, M., Verstappen, S. M. M., Hornberger, M. & Macgregor, A., Feb 2023, In: Seminars in Arthritis and Rheumatism. 58, 152131.Research output: Contribution to journal › Article › peer-review
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Early renal impairment affects hormonal regulators of calcium and bone metabolism and Wnt signalling and the response to vitamin D supplementation in healthy older adults
Christodoulou, M., Aspray, T. J., Piec, I., Washbourne, C., Tang, J. C. Y., Fraser, W. D., Schoenmakers, I. & the VDOP Trial group, May 2023, In: Journal of Steroid Biochemistry and Molecular Biology. 229, 106267.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure)
Prizes
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Fahrenheit Placement Prize for Excellence
Davidson, Rosemary (Recipient), 2004
Prize: Prize (including medals and awards)
Activities
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Referee for research proposals submitted to the Alzheimer’s Association and the French National Research Agency (ANR).
David Vauzour (Reviewer)
2023 → …Activity: Other activity types › Other
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Manuscript referee for various journals (details in comments)
David Vauzour (Reviewer)
2023 → …Activity: Other activity types › Other
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Heliyon (Journal)
David Vauzour (Associate Editor)
14 Nov 2022Activity: Editorial work › Publication editorial role
Press/Media
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Four foods to help with arthritis pain and inflamed joints – from cherries to broccoli (Dec 22)
23/12/22 → 24/12/22
8 items of Media coverage
Press/Media: Press / Media
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Women Positively Ageing: How to protect your brain health
10/07/22
1 Media contribution
Press/Media: Press / Media
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Food Matters Live: How does what you eat affect brain function?
17/06/22
1 Media contribution
Press/Media: Press / Media