Projects per year
Organisation profile
Main achievements have been facilitated by several interdisciplinary and multi-institutional consortia. These include EPRSC/Innovate UK funded GELENZ consortium focused on the new enzymatic routes in generating carbohydrate-based materials (Khimyak, in collaboration with Bath, Bristol and JIC), Marie Curie Industry-Academia Partnership (Morris), EU-funded IMODE interreg partnership (Qi, Fabian). Other sources of funding include UKRI (EPSRC, BBSRC), industrial support (Qi, Saeed, Morris, Khimyak) and cross NRP pump-priming grants (Qi, Khimyak). Wallace joined the cluster as a Research Fellow of Royal Commission of Exhibition of 1851 and developed innovative NMR chemical imaging methods.
- We have developed of novel formulation methodologies including advances in 3D printing (Saeed (EPSRC), Qi), amorphous pharmaceutical materials (Khimyak (EPSRC), Qi (ICS)), soft matter systems (Khimyak (EPSRC/Innovate UK), Round, Wallace), encapsulated solid form of pharmaceuticals (Khimyak, Fabian).
- Advanced molecular level characterisation of pharmaceutical materials at different length and time scales based on the synergy of experimental and computational tools uncovered unprecedented level of detail in structure of polymer based materials (Khimyak, Qi (EU, ICS), Saeed (EPSRC)), co-crystals (Fabian, Khimyak, Round) and nanoscale systems (Morris, Round) and enabled predicting structure/properties in solid-state (Fabian, Khimyak).
- We have developed novel NMR tool-kit for soft matter (EPSRC/Innovate UK), biomaterials (NRP grants), carbohydrate systems (Khimyak, Wallace, cross-NRP collaborations), pharmaceuticals based on the combined application of solution and solid-state methods (Khimyak, Wallace) as well as innovative chemical imaging methods (Wallace).
- Novel pharmaceutical materials: polymer systems for tissue engineering (Saeed), nano-formulations (Morris), graphene based nanomaterials (Khimyak) and soft matter systems (Khimyak, Qi, Wallace).
This research group is led by Prof Yaroslav Khimyak
Collaborations and top research areas from the last five years
Profiles
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Jesus Angulo
- School of Chemistry, Pharmacy and Pharmacology - Honorary Senior Lecturer
- Pharmaceutical Materials and Soft Matter - Member
Person: Honorary, Research Group Member
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Laszlo Fabian
- School of Chemistry, Pharmacy and Pharmacology - Lecturer
- Pharmaceutical Materials and Soft Matter - Member
Person: Research Group Member, Academic, Teaching & Research
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Yaroslav Khimyak
- School of Chemistry, Pharmacy and Pharmacology - Professor in Solid-state NMR
- Pharmaceutical Materials and Soft Matter - Member
Person: Research Group Member, Academic, Teaching & Research
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Using Digital Technologies to Accelerate Healthy Snack Product Innovation
1/09/24 → 28/02/26
Project: Research
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Oscillating pH gradients: a new tool to study i-motif DNA by NMR spectroscopy
1/10/23 → 31/03/27
Project: Research
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3D Printing of Pharmaceutical and Drug Delivery Devices: Progress from Bench to Bedside
Lamprou, D. A. (ed.), Douroumis, D. (ed.) & Qi, S. (ed.), Jul 2024, Wiley.Research output: Book/Report › Book
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Alternative dimethylsulfoniopropionate biosynthesis enzymes in diverse and abundant microorganisms
Wang, J., Curson, A. R. J., Zhou, S., Carrión, O., Liu, J., Vieira, A. R., Walsham, K. S., Monaco, S., Li, C-Y., Dong, Q-Y., Wang, Y., Rivera, P. P. L., Wang, X-D., Zhang, M., Hanwell, L., Wallace, M., Zhu, X-Y., Leão, P. N., Lea-Smith, D. J., Zhang, Y-Z. & 2 others, , Aug 2024, In: Nature Microbiology. 9, 8, p. 1979–1992 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Downloads (Pure) -
An investigation into the effects of ink formulations of semi-solid syringe extrusion 3D printing on the performance of the printed solid dosage forms
Zhang, B., Belton, P. S., Teoh, X. Y., Gleadall, A., Bibb, R. J. & Qi, S., 7 Jan 2024, In: Journal of Materials Chemistry B. 12, 1, p. 131-144 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)6 Downloads (Pure)
Datasets
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Chemoenzymatic synthesis of fluorinated cellodextrins identifies a new allomorph for cellulose‐like materials
Muñoz-García, J. C. (Creator), de Andrade, P. (Contributor), Pergolizzi, G. (Contributor), Gabrielli, V. (Contributor), Nepogodiev, S. (Contributor), Iuga, D. (Contributor), Fabian, L. (Contributor), Nigmatullin, R. (Contributor), Johns, M. A. (Contributor), Harniman, R. (Contributor), Eichhorn, S. J. (Contributor), Angulo, J. (Contributor), Khimyak, Y. (Contributor) & Field, R. A. (Contributor), Wiley, 30 Sep 2020
Dataset
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Data for Rapid determination of the acidity, alkalinity and carboxyl content of aqueous samples by 1H NMR with minimal sample quantity
Wallace, M. (Creator), Lam, K. (Creator), Kuraite, A. (Creator) & Khimyak, Y. (Creator), American Chemical Society, 9 Sep 2020
DOI: 10.1021/acs.analchem.0c02594
Dataset
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Data for: Deriving ligand orientation on weak protein-ligand complexes by DEEP-STD NMR in the absence of protein chemical shift assignment
Nepravishta, R. (Creator), Walpole, S. (Creator), Tailford, L. E. (Creator), Juge, N. (Creator) & Angulo, J. (Creator), University of East Anglia, 2018
Dataset
File
Prizes
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(1) "Bruker - Universidad de Sevilla" Nuclear Magnetic Resonance Prize
Angulo, Jesus (Recipient), 2019
Prize: Prize (including medals and awards)
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(2) UEA Transforming Education Awards: "PhD Supervisor of the Year"
Angulo, Jesus (Recipient), 2019
Prize: Prize (including medals and awards)
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Innovation and Impact Award 2020
Saeed, Aram (Recipient), 7 Feb 2020
Prize: Prize (including medals and awards)
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Pharma Industry Awards UK (judge)
Laszlo Fabian (Presenter)
29 Jul 2024 → 18 Sep 2024Activity: Other activity types › Other
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Current Eye Research (Journal)
Aram Saeed (Peer reviewer)
11 Apr 2024Activity: Editorial work › Publication peer-review
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External examiner of MSc programmes in School of Pharmacy (UCL)
Laszlo Fabian (Examiner)
2024 → 2027Activity: Examination