Projects per year
Organisation profile
Organisation profile
We want to understand how gene regulatory pathways control animal development. There are currently more than 150 diverse chemical modifications found on RNA. RNA modifications affect gene expression by regulating RNA processing, stability and expression. We are using the C. elegans germline development as a model system to study the role of RNA modifications in germ cell proliferation and differentiation.
We aim to
- develop new methodologies to identify modified RNAs
- characterise the biological role of RNA modifying enzymes
- study the interactions between cellular metabolism and RNA modifications
Our research is currently supported by a prestigious UK Research and Innovation Future Leaders Fellowship (UKRI-FLF) awarded to Dr Alper Akay.
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
-
Aduragbemi Adesina
- School of Biological Sciences - Senior Research Associate
- RNA (epi)Genetics Lab - Member
Person: Member, Research & Analogous
-
Alper Akay
- School of Biological Sciences - UKRI Future Leaders Fellow
- Cells and Tissues - Member
- RNA (epi)Genetics Lab - Group Lead
Person: Group Lead, Research Group Member, Academic, Teaching & Research
-
-
Gut Health and Food Safety
Wileman, T., Man, A. & Pearson, T.
Biotechnology and Biological Sciences Research Council
1/04/12 → 31/03/18
Project: Research
-
Cryo-kinetics reveal dynamic effects on the chemistry of human dihydrofolate reductase
Adesina, A. S., Luk, L. Y. P. & Allemann, R. K., 15 Jul 2021, In: ChemBioChem. 22, 14, p. 2410-2414 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Downloads (Pure) -
Enhanced small neutral but not branched chain amino acid transport after epigenetic sodium coupled neutral amino acid transporter‐2 (SNAT2) cDNA expression in myoblasts
Pearson, T., Wendowski, O. & Powell, P. P., Jun 2021, In: Journal of Cachexia, Sarcopenia and Muscle. 12, 3, p. 811-822 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)5 Downloads (Pure) -
Non‐canonical autophagy functions of ATG16L1 in epithelial cells limit lethal infection by influenza A virus
Wang, Y., Sharma, P., Jefferson, M., Zhang, W., Bone, B., Kipar, A., Bitto, D., Coombes, J. L., Pearson, T., Man, A., Zhekova, A., Bao, Y., Tripp, R. A., Carding, S. R., Yamauchi, Y., Mayer, U., Powell, P. P., Stewart, J. P. & Wileman, T., 15 Mar 2021, In: The EMBO Journal. 40, 6, e105543.Research output: Contribution to journal › Article › peer-review
Open AccessFile21 Citations (Scopus)27 Downloads (Pure)
Activities
-
UEA Open Day
Alper Akay (Speaker)
2 Jul 2022Activity: Participating in or organising an event › Open day
-
Jennifer Tullet
Alper Akay (Host)
22 Jun 2022Activity: Hosting a visitor › Hosting an academic visitor
-
Eaton Primary School visit
Alper Akay (Speaker)
15 Mar 2022Activity: Participating in or organising an event › Schools engagement