Alper Akay

Search results

• 2025

  Optimising age-specific insulin signalling to slow down reproductive ageing increases fitness in different nutritional environments

  Sultanova, Z., Shen, A., Hencel, K., Carlsson, H., Crighton, Z., Clifton, D., Akay, A. & Maklakov, A. A., 24 Jan 2025, (E-pub ahead of print) In: Aging Cell.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
• 2024

  U6 snRNA m6A modification is required for accurate and efficient splicing of C. elegans and human pre-mRNAs

  Shen, A., Hencel, K., Parker, M. T., Scott, R., Skukan, R., Adesina, A. S., Metheringham, C. L., Miska, E. A., Nam, Y., Haerty, W., Simpson, G. G. & Akay, A., 27 Aug 2024, In: Nucleic Acids Research. 52, 15, p. 9139–9160 22 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  1 Citation (Scopus)

  13 Downloads (Pure)
• 2021

  The RNA polymerase II subunit RPB-9 recruits the integrator complex to terminate Caenorhabditis elegans piRNA transcription

  Berkyurek, A. C., Furlan, G., Lampersberger, L., Beltran, T., Weick, E-M., Nischwitz, E., Cunha Navarro, I., Braukmann, F., Akay, A., Price, J., Butter, F., Sarkies, P. & Miska, E. A., 1 Mar 2021, In: The EMBO Journal. 40, 5, e105565 .

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  16 Citations (SciVal)

  24 Downloads (Pure)

• Toward genetic modification of plant-parasitic nematodes: Delivery of macromolecules to adults and expression of exogenous mRNA in second stage juveniles

  Kranse, O., Beasley, H., Adams, S., Pires-daSilva, A., Bell, C., Lilley, C. J., Urwin, P. E., Bird, D., Miska, E., Smant, G., Gheysen, G., Jones, J., Viney, M., Abad, P., Maier, T. R., Baum, T. J., Siddique, S., Williamson, V., Akay, A. & Eves-van den Akker, S., Feb 2021, In: G3-Genes Genomes Genetics. 11, 2, jkaa058.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  13 Citations (SciVal)

  16 Downloads (Pure)

• Translational adaptation to heat stress is mediated by RNA 5‐methylcytosine in Caenorhabditis elegans

  Cunha Navarro, I., Tuorto, F., Jordan, D., Legrand, C., Price, J., Braukmann, F., Hendrick, A. G., Akay, A., Kotter, A., Helm, M., Lyko, F. & Miska, E. A., 15 Mar 2021, In: The EMBO Journal. 40, 6, e105496.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  28 Citations (SciVal)

  36 Downloads (Pure)
• 2020

  DEPS-1 is required for piRNA-dependent silencing and PIWI condensate organisation in Caenorhabditis elegans

  Suen, K. M., Braukmann, F., Butler, R., Bensaddek, D., Akay, A., Lin, C-C., Milonaitytė, D., Doshi, N., Sapetschnig, A., Lamond, A., Ladbury, J. E. & Miska, E. A., 25 Aug 2020, In: Nature Communications. 11, 4242 .

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  12 Citations (Scopus)

  18 Downloads (Pure)
• 2019

  Identification of functional long non-coding RNAs in C. elegans

  Akay, A., Jordan, D., Navarro, I. C., Wrzesinski, T., Ponting, C. P., Miska, E. A. & Haerty, W., 18 Feb 2019, In: BMC Biology. 17, 14.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  26 Citations (SciVal)

  13 Downloads (Pure)
• 2018

  Maintaining confidence in the reporting of scientific outputs

  Sarabipour, S., Wissink, E. M., Burgess, S. J., Hensel, Z., Debat, H., Emmott, E., Akay, A., Akdemir, K. & Schwessinger, B., 8 Aug 2018, (Submitted) In: PeerJ.

  Research output: Contribution to journal › Article › peer-review
• 2017

  The helicase aquarius/EMB-4 is required to overcome intronic barriers to allow nuclear RNAi pathways to heritably silence transcription

  Akay, A., Di Domenico, T., Suen, K. M., Nabih, A., Parada, G. E., Larance, M., Medhi, R., Berkyurek, A. C., Zhang, X., Wedeles, C. J., Rudolph, K. L. M., Engelhardt, J., Hemberg, M., Ma, P., Lamond, A. I., Claycomb, J. M. & Miska, E. A., 7 Aug 2017, In: Developmental Cell. 42, 3, p. 241-255.e6 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  47 Citations (Scopus)

  29 Downloads (Pure)

• The profile and dynamics of RNA modifications in animals

  van Delft, P., Akay, A., Huber, S. M., Bueschl, C., Rudolph, K. L. M., Di Domenico, T., Schuhmacher, R., Miska, E. A. & Balasubramanian, S., 1 Jun 2017, In: ChemBioChem. 18, 11, p. 979-984 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  28 Citations (SciVal)

  55 Downloads (Pure)
• 2015

  E. coli OxyS non-coding RNA does not trigger RNAi in C. elegans

  Akay, A., Sarkies, P. & Miska, E. A., 15 Apr 2015, In: Scientific Reports. 5, 9597.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  13 Citations (Scopus)
• 2013

  RNA-binding protein GLD-1/quaking genetically interacts with the mir-35 and the let-7 miRNA pathways in Caenorhabditis elegans

  Akay, A., Craig, A., Lehrbach, N., Larance, M., Pourkarimi, E., Wright, J. E., Lamond, A., Miska, E. & Gartner, A., 1 Nov 2013, In: Open Biology. 3, 11

  Research output: Contribution to journal › Article › peer-review

  Open Access
  17 Citations (SciVal)

• Stress response: Anything that doesn’t kill you makes you stronger

  Gartner, A. & Akay, A., 18 Nov 2013, In: Current Biology. 23, 22, p. R1012-R1014 3 p.

  Research output: Contribution to journal › Article

  Open Access
  4 Citations (Scopus)
• 2008

  Alkylation damage causes MMR-dependent chromosomal instability in vertebrate embryos

  Feitsma, H., Akay, A. & Cuppen, E., 1 Jul 2008, In: Nucleic Acids Research. 36, 12, p. 4047–4056

  Research output: Contribution to journal › Article › peer-review

  Open Access
  16 Citations (Scopus)