Projects per year
Personal profile
Academic Background
Amr has pursued his B.Sc. (excellent with honors) in Chemistry at the School of Sciences, Mansoura University (Egypt) in 2004 and, his M.Sc. in Organic Chemistry (Plant Natural Products Chemistry) at the same University in 2009, before gaining his PhD in Organic Chemistry/Chemical Biology (Marine Natural Products and Biomimetic Synthesis) from the CNRS-ICSN, University of Paris-Saclay, France, in 2016. After pursuing his PhD in France, Amr was affiliated to Mansoura University as an Assistant Professor while also conducting his first Postdoctoral training at the Fungal Natural Products Team at CNRS/MNHN, Sorbonne Universities (France). Since April 2019 up to July 2024, Amr was conducting his second postdoctoral training in Natural Products Biosynthesis (Professor Anne Osbourn's group) at John Innes Centre, Norwich Research Park, UK. Later, in December 2021, Amr has been promoted to an Associate Professor in Organic Chemistry, at Mansoura University, Egypt. In August 2024, Amr accepted a Lecturership position in Chemical Biology at the School of Pharmacy, University of East Anglia, where he embarked on establishing his research group.
Areas of Expertise
Amr is an Organic and Natural Products Chemist. His work covers natural products based drug discovery, including isolation, structure elucidation, biomimetic and biosynthesis.
We are a part of the Chemical Biology and Medicinal chemistry Group at UEA, Norwich Research Park
https://www.uea.ac.uk/groups-and-centres/chemical-biology-and-medicinal-chemistry-group
Career
August 2024-now: Assistant Professor in Chemical Biology, School of Pharmacy, University of East Anglia, Norwich-UK
April 2019-July 2024: Postdoctoral Scientist, Biochemistry and Metabolism Department, The John Innes Centre, Norwich Research Park, Norwich, UK. (Professor Anne Osbourn's group).
January 2022-Now: Associate Professor of Organic Chemistry, School of Sciences, Mansoura University, Mansoura, Egypt.
October 2017- March 2019: Postdoctoral scientist/Attached assistant professor, CNRS-MNHN, Sorbonne Universities, Paris-France.
July 2016- December 2021: Assistant Professor of Organic Chemistry, School of Sciences, Mansoura University, Mansoura, Egypt.
October 2009- July 2016 : Assistant Lecturer, School of Sciences, Mansoura University, Mansoura, Egypt.
April 2007- October 2009: Teaching Assistant, School of Sciences, Mansoura University, Mansoura, Egypt.
Key Research Interests
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Harnessing the incredible Marine Natural Products Biodiversity: Exploring the diverse marine environment to discover and develop novel natural products with potential therapeutic applications.
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Bioinspired and Small Molecule Synthesis and Medicinal Chemistry: Design, synthesis, and evaluation of small molecules inspired by natural products for medicinal chemistry applications.
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Investigating the Biosynthesis Pathway of Pharmacologically Active Natural Products: Studying the biosynthetic pathways of naturally occurring bioactive compounds to understand their production mechanisms and explore potential applications.
Education/Academic qualification
Doctor of Philosophy, Isolation of bioactive marine Natural Products and Bio-inspired Synthesis of Fused Tricyclic Guandinic Analogues , University of Paris-Sud
2012 → 2016
Award Date: 9 May 2016
Master in Science, Isolation and Structure Elucidation of Natural Products from Some Medicinally Important Plant species, Mansoura University
2007 → 2009
Award Date: 19 Oct 2009
Bachelor of Science, Mansoura University
2000 → 2004
Keywords
- Chemistry
- Organic Chemistry
- Natural Products-Based drug Discovery
- Spectroscopy
- Structure Elucidation
- Biosynthesis
- Small Molecule Synthesis
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 1 Active
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Assessment of wound healing properties of medicinal plants: The case of Berlinia confusa
Adjei, S., Amponsah, I. K., Ekuadzi, E., Hamilton, C., Gavrilovic, J., Dillon, O., El-Demerdash, A. & Asante-Kwatia, E., Jan 2025, In: Natural Product Communications. 20, 1Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Downloads (Pure) -
Agro-byproduct valorization of radish and turnip leaves and roots as new sources of antibacterial and antivirulence agents through metabolomics and molecular networking
Ibrahim, R. M., Fayez, S., Eltanany, B. M., Abu-Elghait, M., El-Demerdash, A., Badawy, M. S. E. M., Pont, L., Benavente, F. & Saber, F. R., 15 Mar 2024, In: Scientia Horticulturae. 328, 112924.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus) -
Anthocyanins-dietary natural products with a variety of bioactivities for the promotion of human and animal health
Yeung, A. W. K., Solka, M., Jóźwik, A., Ksepka, N., Matin, M., Wang, D., Zielińska, A., Mohanasundaram, A., Vejux, A., Zarrouk, A., Tewari, D., Horbańczuk, J. O., Lucarini, M., Durazzo, A., Ghzaiel, I., Michalczuk, M., Rezig, L., Tzvetkov, N. T., Matin, F. B., Lizard, G., & 33 others, 10 Apr 2024, In: Animal Science Papers and Reports. 42, 1, p. 5-33 29 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Downloads (Pure) -
Cephalostatins and ritterazines: Distinctive dimeric marine-derived steroidal pyrazine alkaloids with intriguing anticancer activities
Tammam, M. A., Gamal El-Din, M. I., Aouidate, A. & El-Demerdash, A., Oct 2024, In: Bioorganic Chemistry. 151, 107654.Research output: Contribution to journal › Review article › peer-review
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Complete biosynthesis of QS-21 in engineered yeast
Liu, Y., Zhao, X., Gan, F., Chen, X., Deng, K., Crowe, S. A., Hudson, G. A., Belcher, M. S., Schmidt, M., Astolfi, M. C. T., Kosina, S. M., Pang, B., Shao, M., Yin, J., Sirirungruang, S., Iavarone, A. T., Reed, J., Martin, L. B. B., El-Demerdash, A., Kikuchi, S., & 13 others, 23 May 2024, In: Nature. 629, 8013, p. 937-944 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)2 Downloads (Pure)