Projects per year
Personal profile
Administrative Posts
- NRPDTP board representative
- Director of Research (2014 - 2017)
- Theme Leader for Cells and Tissues (2010-2013)
- Organizer CDB Seminars (2010 - 2015)
- Member of Studentship selection panel (2006-2010)
Biography
- 2010 Professor of Developmental Biology
- 2006-10 Reader , University of East Anglia
- 2001-06 Senior Lecturer, University of East Anglia
- 1997-01 Wellcome Trust Career Development Fellow, University of Dundee
- 1996 Lecturer, University of Dundee
- 1994-96 Muscular Dystrophy MDA Postdoctoral Fellow, Harvard Medical School, Boston, USA
- 1992-94 Human Frontiers HFSPO Postdoctoral Fellow, Harvard Medical School, Boston, USA
- 1992 PhD - National Institute for Medical Research, MRC, Mill Hill, London
- 1988 German Diploma (MSc equivalent) - Biology, University of Heidelberg and DKFZ German Cancer Research Center
Key Research Interests
We use the chick embryo as a vertebrate model organism to study embryo development. The lab investigates the mechanisms that control cell fate decisions. We focus on developing somites, the segmental units which give rise to skeletal muscle, cartilage, bone and tendon. How are these different cell types specified? We study cardiac progenitor cells and have characterized their origin and migration towards the heart forming region. The insights obtained improve our understanding of early embryo development and are relevant for stem cell science and regenerative medicine.
Current Research Projects
- Signalling pathways and cytoskeletal dynamics in somite patterning and myogenesis
- The origin and migration of cardiac progenitor cells
- MicroRNA function in skeletal muscle differentiation
Postgraduate Research Opportunities
Please email me to discuss projects and sources of funding.
Areas of Expertise
ResearcherID
http://www.researcherid.com/rid/E-2205-2011
Google Scholar
https://scholar.google.com/citations?user=nC3uCsoAAAAJ&hl=en&oi=ao
Teaching Interests
- Skills for Biologists (4008Y)
- Introduction to Biomedicine (4005Y)
- Genetics (5009A)
- Clinical Genetics (5011A)
- Science communication
- Molecular and Cellular Principles of Development (6012A)
- Undergraduate final year Research Projects (6019Y)
- Frontiers of Molecular Medicine (M201)
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Functional analysis of alkylglycerol monooxygenase; an unexpected modulator of Wnt signalling and embryogenesis
Münsterberg, A. (Principal Investigator) & Wheeler, G. (Co-Investigator)
Biotechnology and Biological Sciences Research Council
1/07/23 → 28/02/27
Project: Research
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Decoding the Role of YAP1 in Hematoendothelial Progenitor Mechanobiology During Early Cardiovascular Development
Münsterberg, A. (Principal Investigator) & Mok, G. F. (Co-Investigator)
1/10/26 → 30/09/29
Project: Training
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Deciphering Conserved Enhancers Regulating Hematoendothelial Development
Mok, G. F. (Principal Investigator) & Münsterberg, A. (Co-Investigator)
1/10/26 → 30/09/29
Project: Training
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Investigating novel cis-regulatory elements associated with genes involved in cardiovascular development and disease
Münsterberg, A. (Principal Investigator) & Giffin, J. (Researcher)
1/08/24 → 31/07/26
Project: Research
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The accessible chromatin landscape of cardiac progenitors: characterizing regulatory elements on a genome-wide scale
Münsterberg, A. (Principal Investigator) & Moxon, S. (Co-Investigator)
1/05/21 → 31/07/24
Project: Research
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Transcriptomics and chromatin accessibility signatures define the cervical-thoracic boundary along the vertebrate axis
Weldon, S. A., Smith, E. L., Schatka, M., Folkes, L., Mok, G. F., Lister, A., Macaulay, I. C., Hearty, W. & Münsterberg, A. E., Sept 2025, In: Developmental Biology. 525, p. 249-258 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Downloads (Pure) -
Single cell RNA-sequencing and RNA-tomography of the avian embryo extending body axis
Mok, G. F., Turner, S., Smith, E. L., Mincarelli, L., Lister, A., Lipscombe, J., Uzun, V., Haerty, W., Macaulay, I. C. & Münsterberg, A. E., 28 May 2024, In: Frontiers in Cell and Developmental Biology. 12, 1382960.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)9 Downloads (Pure) -
Absence of the primary cilia formation gene Talpid3 impairs muscle stem cell function
Martinez-Heredia, V., Blackwell, D., Sebastian, S., Pearson, T., Mok, G. F., Mincarelli, L., Utting, C., Folkes, L., Poeschl, E., Macaulay, I., Mayer, U. & Münsterberg, A., 4 Nov 2023, In: Communications Biology. 6, 1121.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)19 Downloads (Pure) -
A transcriptional and regulatory map of mouse somite maturation
Ibarra-Soria, X., Thierion, E., Mok, G. F., Münsterberg, A. E., Odom, D. T. & Marioni, J. C., 9 Oct 2023, In: Developmental Cell. 58, 19, p. 1983-1995.e7 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)11 Downloads (Pure) -
Combination of phenethyl isothiocyanate and dasatinib inhibits hepatocellular carcinoma metastatic potential through FAK/STAT3/Cadherin signalling and reduction of VEGF secretion
Strusi, G., Suelzu, C. M., Weldon, S., Giffin, J., Münsterberg, A. E. & Bao, Y. (Lead Author), Oct 2023, In: Pharmaceutics. 15, 10, 2390.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)19 Downloads (Pure)
Prizes
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Muscular Dystrophy Association, MDA Postdoctoral Fellow
Münsterberg, A. (Recipient), 1994
Prize: Fellowship awarded competitively
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Wellcome Trust Research Career Development Fellow
Münsterberg, A. (Recipient), 1997
Prize: Fellowship awarded competitively
Activities
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Developmental Dynamics (Journal)
Münsterberg, A. (Editorial board member)
2015 → …Activity: Editorial work › Publication editorial role
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First BSDB/BSMB joint meeting: The Musculoskeletal System: from Development to Disease
Münsterberg, A. (Organiser)
Sept 2014Activity: Participating in or organising an event › Participation in workshop or seminar
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EMBO Symposium Cardiac Biology, from Development to Regeneration, Heidelberg
Münsterberg, A. (Invited speaker)
2013Activity: Participating in or organising an event › Participation in conference
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Gordon Conferences on Myogenesis, Il Ciocco
Münsterberg, A. (Invited speaker)
2013Activity: Participating in or organising an event › Participation in conference
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BBSRC Committee C (External organisation)
Münsterberg, A. (Core Member)
2012Activity: Membership › Committee