Research output per year
Research output per year
- 17 results
Search results
-
2021
Insights into the structure-activity relationship of glycosides as positive allosteric modulators acting on P2X7 receptors
Piyasirananda, W., Beekman, A., Ganesan, A., Bidula, S. & Stokes, L., 1 Feb 2021, In: Molecular Pharmacology. 99, 2, p. 163-174 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)17 Downloads (Pure) -
In silico peptide-directed ligand design complements experimental peptide-directed binding for protein–protein interaction modulator discovery
Howell, L. A. & Beekman, A. M., 1 Feb 2021, In: RSC Chemical Biology. 2, 1, p. 215-219 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)33 Downloads (Pure) -
Peptide directed phthalocyanine-gold nanoparticles for selective photodynamic therapy of EGFR overexpressing cancers
Goddard, Z. R., Beekman, A. M., Cominetti, M. M. D., O'Connell, M. A., Chambrier, I., Cook, M. J., Marin, M. J., Russell, D. A. & Searcey, M., 1 Feb 2021, In: RSC Medicinal Chemistry. 12, 2, p. 288-292 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)26 Downloads (Pure) -
2020
A peptide-duocarmycin conjugate targeting the Thomsen-Friedenreich antigen has potent and selective antitumour activity
Cartwright, O. C., Beekman, A. M., Cominetti, M. M. D., Russell, D. A. & Searcey, M., 15 Jul 2020, In: Bioconjugate Chemistry. 31, 7, p. 1745–1749 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)6 Downloads (Pure) -
2019
A small molecule drug conjugate (SMDC) of DUPA and a duocarmycin built on the solid phase
Beekman, A., Cominetti, M., Cartwright, O., Boger, D. L. & Searcey, M., Dec 2019, In: MedChemComm. 10, 12, p. 2170-2174 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Downloads (Pure) -
Identification of selective protein-protein interaction inhibitors using efficient in silico peptide-directed ligand design
Beekman, A. M., Cominetti, M. M. D., Walpole, S. J., Prabhu, S., O'Connell, M. A., Angulo Alvarez, J. & Searcey, M., 28 Apr 2019, In: Chemical Science. 10, 16, p. 4502-4508 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (Scopus)43 Downloads (Pure) -
2018
Rac1 plays a role in CXCL12 but not CCL3-induced chemotaxis and Rac1 GEF inhibitor NSC23766 has off target effects on CXCR4
Mills, S., Howell, L., Beekman, A., Stokes, L. & Mueller, A., Jan 2018, In: Cellular Signalling. 42, p. 88–96 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Citations (Scopus)25 Downloads (Pure) -
2017
Peptide-directed binding for the discovery of modulators of α-helix-mediated protein-protein interactions: Proof-of-concept studies with the apoptosis regulator Mcl-1
Beekman, A. M., O'Connell, M. A. & Howell, L. A., 21 Aug 2017, In: Angewandte Chemie International Edition. 56, 35, p. 10446–10450 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)31 Downloads (Pure) -
2016
Ravynic acid, an antibiotic polyeneyne tetramic acid from Penicillium sp. elucidated through synthesis
Myrtle, J. D., Beekman, A. M. & Barrow, R. A., 21 Jul 2016, In: Organic & Biomolecular Chemistry. 14, 35, p. 8253-8260 8 p.Research output: Contribution to journal › Article › peer-review
10 Citations (Scopus) -
Small molecule and peptide inhibitors of the pro-survival protein Mcl-1
Howell, L. & Beekman, A., 19 Apr 2016, In: ChemMedChem. 11, 8, p. 802–813 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile32 Citations (Scopus)25 Downloads (Pure) -
2015
Discovery and synthesis of Boletopsins 13 and 14, brominated fungal metabolites of terrestrial origin
Beekman, A. M., Wossa, S. W., Kevo, O., Ma, P. & Barrow, R. A., 28 Aug 2015, In: Journal of Natural Products. 78, 8, p. 2133-2135 3 p.Research output: Contribution to journal › Article › peer-review
10 Citations (Scopus) -
Syntheses of Cytosporones A, C, J, K, and N, Metabolites from Medicinal Fungi
Beekman, A. M. & Barrow, R. A., 5 Jun 2015, In: Australian Journal of Chemistry. 68, 10, p. 1583-1592 10 p.Research output: Contribution to journal › Article › peer-review
8 Citations (Scopus) -
2014
Fungal metabolites as pharmaceuticals
Beekman, A. M. & Barrow, R. A., 19 May 2014, In: Australian Journal of Chemistry. 67, 6, p. 827-843 17 p.Research output: Contribution to journal › Article › peer-review
42 Citations (Scopus) -
Syntheses of the Fungal Metabolites Boletopsins 7, 11, and 12 from the Papua New Guinea Medicinal Mushroom Boletopsis sp.
Beekman, A. M. & Barrow, R. A., 17 Jan 2014, In: The Journal of Organic Chemistry. 79, 3, p. 1017-1024 8 p.Research output: Contribution to journal › Article › peer-review
21 Citations (Scopus) -
2013
First syntheses of the biologically active fungal metabolites pestalotiopsones A, B, C and F
Beekman, A. M., Castillo Martinez, E. & Barrow, R. A., 21 Feb 2013, In: Organic & Biomolecular Chemistry. 11, 7, p. 1109-1115Research output: Contribution to journal › Article › peer-review
18 Citations (Scopus) -
Identification of boletopsin 11 and 12, antibiotics from the traditionally used fungus Boletopsis sp.
Wossa, S. W., Beekman, A. M., Ma, P., Kevo, O. & Barrow, R. A., Jul 2013, In: Asian Journal of Organic Chemistry. 2, 7, p. 565-567 3 p.Research output: Contribution to journal › Article › peer-review
16 Citations (Scopus) -
Stereochemical assignment of the fungal metabolites Pestalotiopsones D and E through enantiopure synthesis
Beekman, A. M. & Barrow, R. A., 22 Nov 2013, In: Journal of Natural Products. 76, 11, p. 2054-2059Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus)