• 2.10 Medical School

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Personal profile

Biography

I graduated from St Bartholomew’s Hospital, University of London in 1985 and trained in general medicine and HIV in London and Bristol.  In 1988, I joined the MRC HIV Clinical Trials Centre as a Trial Physician for one of the first large scale, international HIV trials.  In 1991, I was awarded an MRC training fellowship to continue formal training in clinical trials and epidemiology at the London School of Hygiene and Tropical Medicine. 

In 1993, I moved to the Medicines Control Agency to work as a medical epidemiologist in the post marketing drug evaluation unit where I led the investigation of a number of drug safety issues, including a major project on the relative safety of non aspirin NSAIDs.  I had the opportunity to develop links with organizations using large databases to investigate drug safety, including those at Boston University and the University of Dundee.  Between 1995 and 2000, I continued to work in the area of pharmacovigilance with a period in the US as Medical Epidemiologist with Eli Lilly in Indianapolis and Japan and a period at the Boston Collaborative Drug Surveillance Programme.

In 2000, I returned to the MRC as Senior Scientist/Epidemiologist at the MRC Clinical Trials Unit and began to work on international trials in ovarian and endometrial cancer, where I had the opportunity. In 2010, I completed higher specialist training in Clinical Pharmacology and Therapeutics and was appointed to develop a new clinical trials unit at UCL as Director with wide ranging therapeutic area responsibilities. I then spent a further year in the commercial sector as Managing Director of a specialist pharmacovigilance and drug development company in Cambridge.

In July 2013, I took up the post of Professor of Medicine and Epidemiology at the University of East Anglia and Director of the Norwich Clinical Trials Unit. 

Career

Professional Qualifications

Medicine MB, BS London 1985

Membership of Royal College of Physicians MRCP(UK) 1989

MSc Epidemiology, London School of Hygiene and Tropical Medicine 1993

External Activities

  • National collaborations through the National Cancer Research Institute (Gynae Clinical Studies Group Member 2001-2008)
  • International collaborations e.g. US NCI, Canadian NCIC and International Gynae Cancer InterGroup

Key Research Interests and Expertise

My key research interests are in the design, conduct and analysis of practice changing clinical trials in a wide range of therapeutic areas and novel treatments, particularly involving academic/industry collaborations. 

Recently completed projects:

ICON7 Bevacizumab in the first line treatment of ovarian cancer

ICON6 (Co-CI) Cediranib in relapsed ovarian cancer

Chorus (Co-CI) Neoadjuvant chemotherapy for advanced ovarian cancer

Key Responsibilities

My main administrative role is Director of the Norwich Clinical Trials Unit.

Teaching Interests

  • I am currently supervising an MD Res student at UCL.
  • I will contribute to MBBS teaching and postgraduate teaching and training at UEA.
  • I am committed to developing clinical and non clinical staff working on academic clinical trials.

Network

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