Aram Saeed

Dr

  • 1.09A Chemistry

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Personal profile

Biography

  • Associate Professor (formerly Reader and Senior Lecturer) in Healthcare technologies, School of Pharmacy, University of East Anglia, Norwich, UK (08/2020) 

  • Ignite (alumni) course, Cambridge Judge Business, University of Cambridge, UK. (07/2019)
  • Lecturer in Drug Delivery and Tissue Engineering, School of Pharmacy, University of East Anglia, Norwich, UK. (08/2013)
  • Fellow of Higher Education Academy, School of Pharmacy, University of East Anglia, UK. (2017)
  • Postdoctoral Research Associate, EPSRC Centre for Innovative Manufacturing in Regenerative Medicine, Universities of Nottingham (02/2011)
  • Postdoctoral Research Associate, Network for Excellence for Functional Biomaterials - NUI Galway, Ireland. (11/2009)
  • PhD Toward advanced modular drug and gene delivery system, School of Pharmacy, Nottingham University, UK. (10/2006)

 

https://orcid.org/0000-0003-2903-5875

Selected Publications

  • Induction of Tendon-Specific Markers in Adipose-Derived Stem Cells in Serum-Free Culture Falcon, N. D., Riley, G. & Saeed, A. 29 May 2019, Tissue Engineering. Part C, Methods. 25, 7 
  • Synthesis and Fabrication of Surface-Active Microparticles Using a Membrane Emulsion Technique and Conjugation of Model Protein via Strain-Promoted Azide–Alkyne Click Chemistry in Physiological Conditions. Walden, G., Liao, X., Riley, G., Donell, S., Raxworthy, M. J. & Saeed, A., 20 Mar 2019, I Bioconjugate Chemistry. 30, 3, p. 531–535
  • Saeed, A*; Francini, Nora; White, Lisa; Dixon, James; Gould, Toby; Rashidi, Hassan; Al Ghanami, Racha Cheikh; Hruschka, Veronika; Redl, Heinz; Saunders, Brian R.; Alexander, Cameron; Shakesheff, Kevin M. A thermoresponsive and magnetic colloid for 3D cell expansion and reconfiguration. Advanced Materials. 2015. Vol. 27, No. 4, 27.01.2015, p. 662–668. 
  • Saeed, A*, Newland, Ben; Pandit, Abhay; Wang, Wenxin. The reverse of polymer degradation: in situ crosslinked gel formation through disulfide cleavage. Chemical Communications, Vol. 48, No. 4, 01.01.2012, p. 585-587.  

Key Research Interests and Expertise

My background and expertise span across several disciplines including polymer science (Chemistry), pharmaceutical formulation (Pharmacy), and tissue engineering and regenerative medicine (Biology and Medicine), in particular:

  • Design and synthesis of biodegradable, stimuli sensitive (temperature and pH) and functionalised polymers using controlled/living polymerisation techniques (ROP, RAFT and ATRP),
  • Fabrication of colloidal nano- and micro-carriers for targeted and controlled-release delivery of biopharmaceuticals, conventional drugs, biopolymers and therapeutic proteins.
  • Design and Synthesis of three-dimensional (3D) cell culture materials as injectable and implantable cell delivery systems.

 

My current research is focused on development of novel technology platforms for application in Drug Delivery and Tissue Engineering and Regenerative Medicine

 

  • Acellular 3D biomaterial matrices for use in cellular expansion (In vitro use)
  • Injectable hydrogels as cellular and therapeutic proteins delivery system (In vivo cellular based therapy)
  • 3D printing of complex cellular organisation and tissue-like pattern
  • Design, synthesis and characterisation of polymeric nanoparticulate drug delivery system
  • Targeted therapeutics for cancer treatment with “Smart” nanomaterial with controlled-release features

 

 

 

Administrative Posts

Course Director MPHARM PHARMACY WITH A FOUNDATION YEAR

Course Director BSC PHARMACOLOGY AND DRUG DISCOVERY WITH FOUNDATION YEAR

Disability Liasion Officer 

Tissue Engineering Special Topic Leader

External positions

Recent Appointee In Polymer Science

1 Oct 20151 Oct 2018

Network

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