Projects per year
I spent 6 years researching trauma/personality assessments and treatment and psychometric assessment development with the Ministry of Defence. Then I went into the NHS and undertook an MD on anger characterisation in elderly mentally ill patients.
In the last 10 years I undertook 3 Cochrane reviews in dementia, set up and developed clinical trials in dementia as a chief investigator and regional lead. In 2004 I set UK/US collaborations with colleagues which are ongoing. We have jointly co-developed work on the harms of screening, medication trials in dementia, collaborative care in dementia and the anticholinergic burden scale.
I worked as an NHS consultant for 9 years and developed an applied research strategy. I am presently working on funded projects on inpatient rehabilitation in dementia and assistive technology in dementia.
I lead 4 programmes of research- hospital care in dementia, carer support in dementia, biomarker discovery in dementia and harms of sleeping medication in dementia.
I co-developed the most commonly used anticholinergic assessment tool.
I am working on medication studies, falls and sleep studies in dementia.
I am frailty group lead and am research lead for East of England Ambulance frequent users data study.
I have led and been an active collaborator on designing medication trials in dementia targeting prevention and behaviours.
I have MHRA regulatory experience from leading trials and expertise in trouble shooting recruitment and design issues in clinical trials.
I have expertise in NHS data systems, medical device regulation and App development.
Professional Qualifications and professional memberships
MBBS; Bsc; Mmedsci; MRCPsych; MD
- Chair of Dementia Research Innovation Group
- Theme lead for life long and aging research
- Chair of national NIHR dementia portfolio research group
- Member of EU-Interdem dementia prevention task force
Current research themes are focused on enhancing care for patients with established with dementia and improving early intervention and prevention strategies. My research work is currently funded by the National Institute of Health Research, industry and charitable foundations.
I have a national and international network of research collaborators and I am recognised internationally as a leading researcher in older peoples’ mental health.
Professor of clinical psychiatry August 2015
Reader in mental health August 2014
Clinical Senior Lecturer/Honorary Consultant Psychogeriatrician Norwich Medical School University of East Anglia + Norfolk and Suffolk NHS Foundation Trust-August 2010 ongoing
Clinical Director of Kent and Medway NIHR Comprehensive Local Research Network October 2007- 2010
Consultant Psychiatrist/Senior Lecturer Kent and Medway NHS and Social Care Partnership Trust/University of Kent-August 2001- August 2010
Psychiatric Specialist Registrar Department of Adult Psychiatry, The Fairmile Hospital, Wallingford, Oxford April 2001- August 2001
Psychiatric Specialist Registrar Department of Psychiatry of Old Age, The Fairmile Hospital, Wallingford, Oxford April 2000 - April 2001
Psychiatric Specialist Registrar Department of Psychiatry of Old Age, The Warneford Hospital, Oxford May 1999 - March 2000.
Psychiatric Specialist Registrar RAF Brize Norton Department of Community Psychiatry August 1998 - May 1999
Psychiatric Specialist Registrar Northallerton NHS Trust Yorkshire August 1997- August 1998
Psychiatric Specialist Registrar Ministry of Defence Training Scheme - Colchester Essex August 1997- August 1998
Senior House Officer/Registrar Ministry of Defence Scheme Duchess of Kent's Hospital, Catterick Garrison North Yorkshire October 1996 – August 1997
Senior House Officer/Registrar Northallerton NHS Trust April 1996 – October 1996
Senior House Officer/Registrar Ministry of Defence Training Scheme Duchess of Kent's Hospital, Catterick Garrison, North Yorkshire October 1995 – April 1996 and Princess Alexandra's Hospital, RAF Wroughton, Swindon Wiltshire August 1993 – October 1995
Senior House Officer General Practice Berlin RAF Gatow August 1992-August 1993
House Officer Royal Free Hospital, London January 1992 - August 1992
House Officer Royal East Sussex Hospital, Hastings, Sussex August 1991 - January 1992
- Chair NIHR Portfolio Development Group
- Professional activities
- Consultant Psychogeriatrician
- INTERDEM prevention task force board member
Key Research Interests
My research interests cover a wide range from bioscience through epidemiology, psychological interventions and health services research. My main areas of work have involved evidence based mental health, pharmacological and non-pharmacological interventions in dementia, collaborative projects in neurology and UK/US studies in dementia; both interventions and outcome research at the interface of primary and secondary care. I have been involved in 7 clinical trials of investigational medicinal products as lead and co-investigator.
Currently I am pursuing a research strategy of novel medication usage for dementia, health service research in the UK and USA in dementia and protection of cognition in vulnerable hospitalised elders.
I am one of the Dementia Research Directors in the UK for DeNDRoN.
Internationally I have links with the Das Deutsche Zentrum für Neurodegenerative Erkrankungen DZNE which has led to publications and projects
I have had a collaboration with the Indiana University Center for Aging Research since 2004 which has led to research bids and the collaboration has supported my interest in implementation research.
I am involved in the East of England NIHR Applied Reseach Collaboration- board member of comorbidity theme.
Administration posts and responsibilities (including roles)
Chair of Dementia Research Innovation Group
Theme Lead Life long Aging theme
Implementation - how education can change practice
- Module 11(Psychiatry) MB BS
- MB BS Examiner
- HSC Educator
- External Examiner MSC Brighton Medical School
Theme lead life long aging
Chair of national NIHR dementia portfolio development group
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Doctor of Medicine, University College London
Award Date: 1 Jan 2011
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The impact of acute systemic inflammation upon cerebrospinal fluid and blood biomarkers of brain inflammation and injury in dementia: a study in acute hip fracture and memory clinic patients
1/11/16 → 15/01/23
Secchi, A., Mamayusupova, H., Sami, S., Maidment, I., Coulton, S., Myint, P. K. & Fox, C., Aug 2022, In: Age and Ageing. 51, 8, afac196.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile1 Downloads (Pure)
DHA-enriched fish oil ameliorates deficits in cognition associated with menopause and the APOE4 genotype in rodentsPontifex, M. G., Martinsen, A., Saleh, R. N. M., Harden, G., Fox, C., Muller, M., Vauzour, D. & Minihane, A-M., 1 May 2022, In: Nutrients. 14, 9, 1698.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile7 Downloads (Pure)
Banerjee, S., Jones, C., Wright, J., Grosvenor, W., Hebditch, M., Hughes, L., Feeney, Y., Farina, N., Mackrell, S., Nilforooshan, R., Fox, C., Bremner, S. & Daley, S., Jul 2021, In: International Journal of Geriatric Psychiatry. 36, 7, p. 1011-1019 9 p.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile2 Citations (Scopus)11 Downloads (Pure)
APOE4 genotype exacerbates the impact of menopause on cognition and synaptic plasticity in APOE‐TR micePontifex, M. G., Martinsen, A., Saleh, R. N. M., Harden, G., Tejera, N., Müller, M., Fox, C., Vauzour, D. & Minihane, AM., May 2021, In: The FASEB Journal. 35, 5, e21583.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile8 Citations (Scopus)31 Downloads (Pure)
Assistive technology and telecare to maintain independent living at home for people with dementia: the ATTILA RCTGathercole, R., Bradley, R., Harper, E., Davies, L., Pank, L., Lam, N., Davies, A., Talbot, E., Hooper, E., Winson, R., Scutt, B., Montano, V. O., Nunn, S., Lavelle, G., Lariviere, M., Hirani, S., Brini, S., Bateman, A., Bentham, P., Burns, A. & 12 others, , 1 Mar 2021, In: Health Technology Assessment. 25, 19, p. 1-156 156 p.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile4 Citations (Scopus)40 Downloads (Pure)