Darrell Green

Dr

  • 01.01A Bio-Medical Research Centre (BMRC)

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Personal profile

Key Research Interests

I am a molecular biologist interested in RNA silencing. We use several model systems (human, mouse, virus, etc.). Our research combines genetics, cell and molecular biology with next generation sequencing and bioinformatics to study the role of microRNAs in various biological processes. 

 

Current Research Projects 

  • The role of small RNAs and lncRNAs in cancer
  • Investigating miR-140 and RUNX2 in embryonic development 
  • Single cell RNA-seq in circulating tumour cells
  • Biological function of mRNA and Y RNA structure
  • Improving methods in next generation sequencing studies 

 

Life in our research group 

Our lab is based in the Biomedical Research Centre (BMRC) on the UEA main campus. We use molecular techniques to study small RNAs that regulate the expression of protein coding genes. Our research is a mix of basic science and translational medicine. The weekly lab meeting is shared with several other groups interested in molecular disease mechanisms.  

 

Ph.D. Positions 

Click here for current Ph.D. opportunities at Norwich Medical School. Please feel free to email me to discuss projects outside of these areas and alternative funding sources. 

 

Postdocs & Fellows 

Please feel free to approach me to discuss possibilities. 

Career

  • Lecturer in RNA Biology, University of East Anglia (2018-present)
  • Senior Research Associate, University of East Anglia (2017-2018)
  • Ph.D. Molecular Biology, University of East Anglia (2017)
  • Research Associate, University of East Anglia (2010-2013)
  • Geneticist, Addenbrooke's Hospital (2009-2010)
  • B.Sc. (Hons) Biology, University of East Anglia (2009)

External Activities

  • Editorial Board Member for Journal of Bone Oncology
  • Editorial Board Member for FEBS Open BIO
  • Grant reviewer for Big C
  • Board of Trustees for Bone Cancer Research Trust
  • Project Leader for Genomics England 100,000 Genomes Project
  • Member of European FOSTER consortium (WP1: Biology) 
  • Medical Writer for Ewing Sarcoma Research Trust 
  • Invited speaker to meetings in the UK and USA 

Teaching Interests

  • Year 1 PBL
  • Year 1 Genetics
  • Year 2 Biochemistry
  • Year 3 Cancer Genetics
  • Year 3 Clinical Biochemistry
  • Year 3 Research Dissertation
  • M.Res. Clinical Science 
  • Ph.D. Biomedicine 

Administrative Posts

  • MBBS Applicant Interview Panel
  • MBBS Undergraduate Personal Advisor
  • MBBS Year 2 SAQ Examiner 
  • PGCert Clinical Education Personal Advisor 
  • M.Res. Clinical Science Examiner 
  • M.Sc. Clinical Research Examiner 

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Network

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