Personal profile
Career
- Operations Manager, Norwich Clinical Trials Unit (April 2015 to Current)
- Clinical Trials Project Manager/QA Lead, Norwich Clinical Trials Unit (March 2015 to April 2015)
- Senior Researcher, Research in Real Life Ltd and Optimum Patient Care Ltd (November 2007 to February 2015)
- Research Associate and UK CF Database Fellow, Institute of Health, University of East Anglia, 2004 to October 2007.
- UK CF Database Fellow, Maternal & Child Health Sciences, University of Dundee, 2001 to 2004
- Postdoctoral Research Fellow and Clinical Trials Coordinator, Asthma & Allergy Research Group, University of Dundee. 2000 to 2001
- Research Assistant and Clinical Trials Coordinator, Asthma & Allergy Research Group, University of Dundee. 1997 to 2000
- Research Assistant on project entitled ‘Predicting Drug Absorption From the Gastrointestinal Tract’, University of Manchester. 1993 to 1997
Academic Background
- BSc(Hons) in Biomedical Technology, Sheffield Hallam University, 1993
- PhD entitled ‘Regulation of Epithelial Tight Junctions’, Schools of Medicine and Pharmacy, University of Manchester, 2000.
Key Research Interests
My research interests are:
- Efficient trial delivery methodology with specific interest in research delivery methods in primary care, care home and transitional care environments
- Health policy related to diagnosis and management of chronic disease
Research Group or Lab Membership
Population Health, Health Economics, BioMed
Teaching Interests
I deliver the 'Research Design Service and Clinical Trial Units and the Role of the PI’ lecture for the Foundations of Clinical Research module of the UEA MSc in Clinical Research
Education/Academic qualification
Doctor of Philosophy, Regulation of Epithelial Tight Junctions, University of Manchester
Award Date: 1 Jan 2000
Bachelor of Science, Biomedical Technology, Sheffield Hallam University
Award Date: 1 Jan 1993
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Collaborations and top research areas from the last five years
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Matching support to needs: A children’s social care RCT testing a standardised comprehensive assessment of the mental health needs of young people in care
Sims, E. (Principal Investigator), Hammond, M. (Co-Investigator), Hammond, M. (CTU Role), Pond, M. (CTU Role) & Sims, E. (CTU Role)
National Institute for Health and Care Research
1/06/25 → 30/11/28
Project: Research
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Spatial Inattention Grasping Therapy (SIGHT) for rehabilitation of spatial neglect poststroke: a randomised-controlled multicentre efficacy trial with embedded mechanistic study of determinants of therapy response
Rossit, S. (Principal Investigator), Broomfield, N. (Co-Investigator), Pomeroy, V. (Co-Investigator), Clark, A. (CTU Role), Hammond, M. (CTU Role), Pond, M. (CTU Role) & Sims, E. (CTU Role)
National Institute for Health and Care Research
1/01/25 → 29/02/28
Project: Research
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OPTIMISing personal care assistance for people with advancED DEMentia to reduce refusals of CARE in care homes (OPTIMISED-DEMCARE): intervention co-development and feasibility testing
Backhouse, T. (Principal Investigator), Hammond, M. (Co-Investigator), Barton, G. (CTU Role), Pond, M. (CTU Role), Shepstone, L. (CTU Role) & Sims, E. (CTU Role)
National Institute for Health and Care Research
1/06/24 → 31/01/29
Project: Fellowship
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Optimising the deLIvery of Mental health support to adolescents in care vIa low-inTensity LifE Story work: a realist evaluation with co-deSign and feasibility trial [LIMITLESS 2]
Hammond, S. (Principal Investigator), Hardeman, W. (Co-Investigator), Neil, B. (Co-Investigator), Shepstone, L. (Co-Investigator), Turner, D. (Co-Investigator), Katangwe-Chigamba, T. (CTU Role), Pond, M. (CTU Role) & Sims, E. (CTU Role)
National Institute for Health and Care Research
1/05/24 → 31/10/27
Project: Research
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CompreHensive geriAtRician-led MEdication Review (CHARMER)
Clark, A. (Principal Investigator), Colles, A. (CTU Role), Goodall, K. (CTU Role), Hammond, M. (CTU Role), Hojas Garcia, E. (CTU Role), Pond, M. (CTU Role), Sims, E. (CTU Role), Stirling, S. (CTU Role), Swart, A. M. (CTU Role) & Turner, D. (CTU Role)
National Institute for Health and Care Research
1/01/22 → 31/08/26
Project: Research
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Leukotriene antagonists as first-line or add-on asthma controller therapy
Price, D., Musgrave, S. D., Shepstone, L., Hillier, E. V., Sims, E. J., Gilbert, R. F. T., Juniper, E. F., Ayres, J. G., Kemp, L., Blyth, A., Wilson, E. C. F., Wolfe, S., Freeman, D., Mugford, M., Murdoch, J. & Harvey, I., 5 May 2011, In: New England Journal of Medicine. 364, 18, p. 1695-1707 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile232 Citations (Scopus)37 Downloads (Pure) -
The cost effectiveness of leukotriene receptor antagonists versus long acting beta-2 agonists as add-on therapy to inhaled corticosteroids for asthma: A pragmatic trial
Wilson, E. C. F., Price, D., Musgrave, S. D., Sims, E. J., Shepstone, L., Murdoch, J., Mugford, H. M., Blyth, A., Juniper, E. F., Ayres, J. G., Wolfe, S., Freeman, D., Gilbert, R. F. T., Hillyer, E. V. & Harvey, I., Jul 2010, In: PharmacoEconomics. 28, 7, p. 597-608 12 p.Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus) -
Economic implications of newborn screening for cystic fibrosis: a cost of illness retrospective cohort study
Sims, E. J., Mugford, M., Clark, A. B., Aitken, D., McCormick, J., Mehta, G. & Mehta, A., 2007, In: The Lancet. 369, 9568, p. 1187-1195 9 p.Research output: Contribution to journal › Article
81 Citations (Scopus) -
Cystic fibrosis diagnosed after two months of age leads to worse outcomes and requires more therapy
Sims, E. J., Clark, A., McCormick, J., Metha, G., Connett, G. & Metha, A., 2007, In: Pediatrics. 119, 1, p. 19-28 10 p.Research output: Contribution to journal › Article
118 Citations (Scopus) -
Evaluation of the CompreHensive geriAtRician-led MEdication Review (CHARMER) deprescribing intervention in hospital: protocol for a cluster randomised stepped-wedge trial
Wright, D. J., Alldred, D. P., Scott, S., Atkins, B., Clark, A. B., Colles, A., Hammond, A., Jones, C. E. L., Martin-Kerry, J. M., Patel, M., Sims, E., Turner, D., Witham, M. & Bhattacharya, D., 18 Mar 2026, In: BMJ Open. 16, 3, e107396.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Downloads (Pure)
Prizes
Activities
- 6 Other
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Norwich Clinical Trials Unit representative on NNUH/UEA Joint Research Office Research Governance Committee (February 2018 onwards)
Sims, E. (Contributor)
2018 → …Activity: Other activity types › Other
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Norwich Clinical Trials Unit representative on UKCRC CTU QA Forum (March 2015 onwards)
Sims, E. (Contributor)
2015 → …Activity: Other activity types › Other
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Norwich Clinical Trials Unit lead representative on NNUH/UEA Joint Research Office Operations Group (March 2015 onwards)
Sims, E. (Contributor)
2015 → …Activity: Other activity types › Other
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Norwich Clinical Trials Unit lead representative on NNUH/UEA Joint Research Office Research Governance Operations Group (March 2015 onwards)
Sims, E. (Contributor)
2015 → …Activity: Other activity types › Other
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Provide mentoring support on QA and Operational issues for CTUs seeking Provisional or Full Accreditation
Sims, E. (Advisor)
2006 → …Activity: Other activity types › Other