Projects per year
Dr Helen Murphy is a Professor of Medicine (Diabetes and Antenatal Care) at the University of East Anglia, and a practicing clinician (Norfolk & Norwich University Hospital NHS Trust since 2015, Cambridge University NHS Foundation Trust since 2006).
She runs a diabetes pregnancy research programme which aims to support women with diabetes to achieve the pregnancy glucose targets required for optimal mother and baby health outcomes. She co-led the CONCEPTT Continuous Glucose Monitoring (CGM) trial across 31 international sites. CONCEPTT demonstrated health benefits for mothers with type 1 diabetes, their newborn infants and the potential for substantial healthcare cost savings. In addition to important scientific contributions, building research infrastructure and supporting the next generation of clinical academics, data from CONCEPTT led to changes in clinical practice, such that CGM is now the recognised standard of care for pregnant women with type 1 diabetes.
She works with a multidisciplinary team of diabetes and obstetric clinicians, engineers, and social scientists to develop and evaluate closed-loop insulin delivery systems, suitable for use during pregnancy. Her work demonstrating that closed-loop systems have the potential to transform the future clinical management of type 1 diabetes pregnancy was published in the New England Journal of Medicine and recognised as a landmark advance in the Nature Milestones in Diabetes.
Helen also serves as clinical lead for the National Pregnancy in Diabetes (NPID) audit, which is the largest population-based study in diabetes pregnancy. Data from NPID directly informs diabetes and maternity healthcare policy.
Supported by JDRF, Diabetes UK, and the NIHR, her research is changing the management of diabetes in pregnancy. Helen serves on several research committees, the editorial board for Diabetes Care, Diabetologia, and is a regular contributor to national and international scientific meetings.
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ADAPT – Automated insulin Delivery Among Pregnant women with Type 1 diabetes
Murphy, H., Alibert, L., Shepstone, L., Sims, E., Stirling, S. & Swart, A. M.
National Institute for Health and Care Research
1/01/18 → 31/03/23
Pre‐pregnancy health of women with pre‐existing diabetes or previous gestational diabetes: Analysis of pregnancy risk factors and behavioural data from a digital toolFlynn, A. C., Robertson, M., Kavanagh, K., Murphy, H. R., Forde, R., Stephenson, J., Poston, L. & White, S. L., Feb 2023, In: Diabetic Medicine. 40, 2, e15008.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile4 Downloads (Pure)
AiDAPT: automated insulin delivery amongst pregnant women with type 1 diabetes: a multicentre randomized controlled trial – study protocolLee, T. T. M., Collett, C., Man, M-S., Hammond, M., Shepstone, L., Hartnell, S., Gurnell, E., Byrne, C., Scott, E. M., Lindsay, R. S., Morris, D., Brackenridge, A., Dover, A. R., Reynolds, R. M., Hunt, K. F., McCance, D. R., Barnard-Kelly, K., Rankin, D., Lawton, J., Bocchino, L. E. & 6 others, , 5 Apr 2022, In: BMC Pregnancy and Childbirth. 22, 282.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile6 Downloads (Pure)
A mobile phone app for the prevention of type 2 diabetes in Malaysian women with gestational diabetes mellitus: Protocol for a feasibility randomized controlled trialBenton, M., Iman, I., Goldsmith, K., Forbes, A., Ching, S. M., Papachristou Nadal, I., Guess, N., Murphy, H. R., Mohd Yusof, B-N., Baharom, A., Mahamad Sobri, N. H., Basri, N. I., Salim, M. S., Ismail, I. Z., Hassan, F., Ismail, K. & Chew, B. H., 8 Sep 2022, In: JMIR Research Protocols. 11, 9, e37288.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile1 Downloads (Pure)
An integrated primary care-based programme of PRE-Pregnancy cARE to improve pregnancy outcomes in women with type 2 Diabetes (The PREPARED study): protocol for a multi-method study of implementation, system adaptation and performanceForde, R., Abiola, O., Anderson, J., Bick, D., Brackenridge, A., Banerjee, A., Chamley, M., Chua, K., Hopkins, L., Hunt, K., Murphy, H. R., Rogers, H., Romeo, R., Shearer, J., Winkley, K. & Forbes, A., 13 Apr 2022, In: BMC Primary Care. 23, 1, 76.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile1 Citation (Scopus)1 Downloads (Pure)
Continuous glucose monitoring metrics and birthweight: informing management of type 1 diabetes throughout pregnancyScott, E. M., Murphy, H. R., Kristensen, K. H., Feig, D. S., Kjölhede, K., Englund-Ogge, L., Berntop, K. E. & Law, G. R., Aug 2022, In: Diabetes Care. 45, 8, p. 1724–1734 11 p.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile2 Citations (Scopus)1 Downloads (Pure)