Projects per year
Personal profile
Biography
Dr Helen Murphy is a Professor of Medicine (Diabetes and Antenatal Care) at the University of East Anglia, and a practicing clinician (Norfolk & Norwich University Hospital NHS Trust since 2015, Cambridge University NHS Foundation Trust since 2006).
She runs a diabetes pregnancy research programme which aims to support women with diabetes to achieve the pregnancy glucose targets required for optimal mother and baby health outcomes. She co-led the CONCEPTT Continuous Glucose Monitoring (CGM) trial across 31 international sites. CONCEPTT demonstrated health benefits for mothers with type 1 diabetes, their newborn infants and the potential for substantial healthcare cost savings. In addition to important scientific contributions, building research infrastructure and supporting the next generation of clinical academics, data from CONCEPTT led to changes in clinical practice, such that CGM is now the recognised standard of care for pregnant women with type 1 diabetes.
She works with a multidisciplinary team of diabetes and obstetric clinicians, engineers, and social scientists to develop and evaluate closed-loop insulin delivery systems, suitable for use during pregnancy. Her work demonstrating that closed-loop systems have the potential to transform the future clinical management of type 1 diabetes pregnancy was published in the New England Journal of Medicine and recognised as a landmark advance in the Nature Milestones in Diabetes.
Helen also serves as clinical lead for the National Pregnancy in Diabetes (NPID) audit, which is the largest population-based study in diabetes pregnancy. Data from NPID directly informs diabetes and maternity healthcare policy.
Supported by JDRF, Diabetes UK, and the NIHR, her research is changing the management of diabetes in pregnancy. Helen serves on several research committees, the editorial board for Diabetes Care, Diabetologia, and is a regular contributor to national and international scientific meetings.
Collaborations and top research areas from the last five years
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PROTECT PRegnancy Outcomes using continuous glucose monitoring TEChnology in pregnant women with Type 2 diabetes: A multicentre randomised controlled trial of the clinical and cost-effectiveness of using continuous glucose monitoring in pregnant women with type 2 diabetes
Murphy, H., Collett, C., Hammond, M., Pond, M. & Shepstone, L.
National Institute for Health and Care Research
1/05/23 → 30/04/27
Project: Research
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Automated closed-loop insulin delivery for the management of type 1 diabetes during pregnancy: the AiDAPT RCT
Lee, T., Collett, C., Bergford, S., Hartnell, S., Scott, E. M., Lindsay, R. S., Hunt, K. F., McCance, D. R., Barnard-Kelly, K., Rankin, D., Lawton, J., Reynolds, R. M., Flanagan, E., Hammond, M., Shepstone, L., Willinska, M. E., Sibayan, J., Kollman, C., Beck, R., Hovorka, R., & 1 others , 1 Apr 2024, In: Efficacy and Mechanism Evaluation. 11, 7Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Downloads (Pure) -
Impact of COVID-19 on gestational diabetes pregnancy outcomes in the UK: A multicentre retrospective cohort study
Mclennan, N-M., Lindsay, R., Saravanan, P., Sukumar, N., White, S. L., von Dadelszen, P., Burden, C., Hunt, K., George, P., Hirst, J. E., Lattey, K., Lee, T. T. M., Murphy, H. R., Scott, E. M., Magee, L. A., Reynolds, R. M. & the Diabetes in Pregnancy Working Group, May 2024, In: BJOG: An International Journal of Obstetrics and Gynaecology. 131, 6, p. 858-868 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)3 Downloads (Pure) -
Pregnancy Outcomes in Type 2 Diabetes: a systematic review and meta-analysis
Clement, N. S., Abul, A., Farrelly, R., Murphy, H. R., Forbes, K., Simpson, N. A. B. & Scott, E. M., 9 Dec 2024, (E-pub ahead of print) In: American Journal of Obstetrics and Gynecology.Research output: Contribution to journal › Article › peer-review
Open Access -
Proactive review for people with diabetes in hospital: a cluster randomised feasibility trial with process evaluation, protocol V3.1
Lake, A. K., Bansiya, V., Davenport, K., Murdoch, J., Murphy, H. R., Smith, T. O., Clark, A. & Arthur, A., 11 Jun 2024, In: Pilot and Feasibility Studies. 10, 88.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Downloads (Pure) -
Technology advances in diabetes pregnancy: Right technology, right person, right time
McLean, A., Maple-Brown, L. & Murphy, H. R., Oct 2024, In: Diabetologia. 67, 10, p. 2103-2113 11 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile2 Citations (Scopus)2 Downloads (Pure)