Personal profile
Academic Background
James gained his PhD in Bionanotechnology at Cranfield University as part of a CASE studentship in collaboration with Unilever, Colworth. here he worked on glycoproteins at interfaces and worked towards understanding how molecules feel at biological intercfaces using OWLS (optical waveguide lightmode spectroscopy). Next, he moved to the chemistry department, Cambridge to work in the Klenerman group where he used single moelecule imaging to determine the T cell receptor stochiometry. A three year postdoc at UEA, working in Andrea Munsterbergs group saw James tracking heart progenitors in chick embryos. Prior to taking up the role as bioimaging facility manager at UEA, James spent the previous 5 years back at the Klenerman lab working across immunotherapy and advanced microscopy projects.
Collaborations and top research areas from the last five years
Projects
- 3 Finished
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Investigating cellular plasticity in the avian primitive streak
Biotechnology and Biological Sciences Research Council
1/04/16 → 30/09/19
Project: Research
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Action potentials - a light hearted approach
John & Pamela Salter Charitable Trust (The)
1/04/13 → 31/12/13
Project: Research
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Evidence that G-quadruplexes form in pathogenic fungi and represent promising antifungal targets
Middleton, G., Mahamud, F. O., Storer, I. S. R., Williams-Gunn, A., Wostear, F., Abdolrasouli, A., Barclay, E., Bradford, A., Steward, O., Schelenz, S., McColl, J., Lézé, B., van Rhijn, N., da Silva Dantas, A., Furukawa, T., Warren, D., Waller, Z. A. E. & Bidula, S., 8 Dec 2025, In: EMBO Molecular Medicine. 17, 12, p. 3636–3656 21 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure) -
The TECPR1:ATG5-ATG12 complex conjugates LC3/ATG8 to damaged lysosomes that expose luminal glycans in response to osmotic imbalance
Wang, Y., Jefferson, M., Ramos, M., Whelband, M., Kreuzer, K., Khuu, G., Lazarou, M., Mccoll, J., Lazenby, J., Whitchurch, C. B., Verkade, P., Mayer, U. & Wileman, T., 2025, In: Autophagy Reports. 4, 1, 2476218.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)5 Downloads (Pure) -
Piezo1-mediated regulation of smooth muscle cell volume in response to enhanced extracellular matrix rigidity
Johnson, R. T., Solanki, R., Wostear, F., Ahmed, S., Taylor, J. C. K., Rees, J., Abel, G., McColl, J., Jørgensen, H. F., Morris, C. J., Bidula, S. & Warren, D. T., Jun 2024, In: British Journal of Pharmacology. 181, 11, p. 1576-1595 20 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Citations (Scopus)25 Downloads (Pure) -
Accelerating paint superresolution imaging by active probe control
Sanders, E. W., Carr, A. R., Bruggeman, E., Koerbel, M., Santos, A. M., McColl, J. T., O'Holleran, K., Klenerman, D., Davis, S. J., Ponjavic, A. & Lee, S. F., 11 Feb 2022, In: Biophysical Journal. 121, 3 Supplement 1, p. 140a 1 p.Research output: Contribution to journal › Abstract › peer-review
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Imaging T-cell activation: Topography and features of early T-cell contacts
Körbel, M., Jenkins, E., McColl, J. T., O'Brien-Ball, C., Lippert, A. H., Santos, A. M., Lee, S. F., Davis, S. J. & Klenerman, D., 11 Feb 2022, In: Biophysical Journal. 121, 3 Supplement, p. 150a-151a 2 p.Research output: Contribution to journal › Abstract › peer-review