Projects per year
Personal profile
Academic Background
I am a scientific group leader working with pluripotent stem cells at Norwich Medical School, University of East Anglia, UK. I completed my PhD at the University of Birmingham with a focus on mesenchymal stem cells and the extracellular matrix. I then undertook post-doctoral training at the University of Nottingham developing automated manufacture technologies for human pluripotent stem cells. I was later appointed as a senior research fellow, using CRISPR gene editing and hiPSCs as tools to investigate cardiovascular disease, before setting up my own group at UEA in 2019
Website: https://www.smithlabuea.com/
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Identifying novel SNORD116 targets and signalling pathways
Foundation for Prader-Willi Research
1/03/25 → 31/08/26
Project: Research
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Do snoRNAs govern genotype-phenotype interactions in hypertrophic cardiomyopathy?
1/06/23 → 31/05/27
Project: Research
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Investigating cardiomyocyte communication in hypertrophic cardiomyopathy
1/03/20 → 1/09/22
Project: Research
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Footprints in the Sno: Investigating the cellular and molecular mechanisms of SNORD116
Holmes, T. L., Chabronova, A., Denning, C., James, V., Peffers, M. J. & Smith, J. G. W., Mar 2025, In: Open Biology. 15, 3, 240371.Research output: Contribution to journal › Review article › peer-review
Open AccessFile -
Myocardial inflammation after elective percutaneous coronary intervention
Merinopoulos, I., Bhalraam, U., Kasmai, B., Hewson, D., Greenwood, R., Eccleshall, S. C., Smith, J., Tsampasian, V. & Vassiliou, V., 1 Jul 2024, (E-pub ahead of print) In: Hellenic Journal of Cardiology.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Perlecan (HSPG2) promotes structural, contractile, and metabolic development of human cardiomyocytes
Johnson, B. B., Cosson, M-V., Tsansizi, L. I., Holmes, T. L., Gilmore, T., Hampton, K., Song, O-R., Vo, N. T. N., Nasir, A., Chabronova, A., Denning, C., Peffers, M. J., Merry, C. L. R., Whitelock, J., Troeberg, L., Rushworth, S. A., Bernardo, A. S. & Smith, J. G. W., 23 Jan 2024, In: Cell Reports. 43, 1, 113668.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)46 Downloads (Pure) -
SnoRNAs in cardiovascular development, function, and disease
Chabronova, A., Holmes, T. L., Hoang, D. M., Denning, C., James, V., Smith, J. G. W. & Peffers, M. J., Jun 2024, In: Trends in Molecular Medicine. 30, 6, p. 562-578 17 p.Research output: Contribution to journal › Review article › peer-review
Open Access1 Citation (Scopus) -
Circulating intermediate monocytes CD14++CD16+ are increased after elective percutaneous coronary intervention
Merinopoulos, I., Bhalraam, U., Holmes, T., Tsampasian, V., Corballis, N., Gunawardena, T., Sawh, C., Maart, C., Wistow, T., Ryding, A., Eccleshall, S. C., Smith, J. & Vassiliou, V. S., 14 Dec 2023, In: PLoS One. 18, 12, e0294746.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)9 Downloads (Pure)