Projects per year
I am a scientific group leader working with pluripotent stem cells at Norwich Medical School, University of East Anglia, UK. I completed my PhD at the University of Birmingham with a focus on mesenchymal stem cells and the extracellular matrix. I then undertook post-doctoral training at the University of Nottingham developing automated manufacture technologies for human pluripotent stem cells. I was later appointed as a senior research fellow, using CRISPR gene editing and hiPSCs as tools to investigate cardiovascular disease, before setting up my own group at UEA in 2019
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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- 1 Finished
Investigating cardiomyocyte communication in hypertrophic cardiomyopathy
1/03/20 → 1/09/22
Modelling metabolic shifts during cardiomyocyte differentiation, iron deficiency and transferrin rescue using human pluripotent stem cellsJohnson, B., Reinhold, J., Holmes, T., Moore, J. A., Cowell, V., Bernardo, A. S., Rushworth, S., Vassiliou, V. & Smith, J., Jan 2022, In: Metabolites. 12, 1, 9.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile3 Citations (Scopus)11 Downloads (Pure)
Quantifiable correlation of ToF‐SIMS and XPS data from polymer surfaces with controlled amino acid and peptide contentTaylor, M., Simoes, F., Smith, J., Genapathy, S., Canning, A., Lledos, M., Chan, W. C., Denning, C., Scurr, D. J., Steven, R. T., Spencer, S. J., Shard, A. G., Alexander, M. R. & Zelzer, M., Apr 2022, In: Surface and Interface Analysis. 54, 4, p. 417-432 16 p.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile5 Downloads (Pure)
The role of inflammation in percutaneous coronary intervention, from balloon angioplasty to drug eluting stentsMerinopoulos, I., Gunawardena, T., Corballis, N., Tsampasian, V., Eccleshall, S. C., Smith, J. & Vassiliou, V. S., 5 Jul 2022, (E-pub ahead of print) In: Minerva Cardiology and Angiology.
Research output: Contribution to journal › Review article › peer-review
Transcriptomic analysis of cardiomyocyte extracellular vesicles in hypertrophic cardiomyopathy reveals differential snoRNA cargoJames, V., Nizamudeen, Z. A., Lea, D., Dottorini, T., Holmes, T. L., Johnson, B. B., Arkill, K. P., Denning, C. & Smith, J. G. W., 16 Dec 2021, In: Stem Cells and Development. 30, 24, p. 1215-1227 13 p.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile5 Citations (Scopus)7 Downloads (Pure)
Isogenic models of hypertrophic cardiomyopathy unveil differential phenotypes and mechanism-driven therapeuticsBhagwan, J. R., Mosqueira, D., Chairez-Cantu, K., Mannhardt, I., Bodbin, S. E., Bakar, M., Smith, J. G. W. & Denning, C., Aug 2020, In: Journal of Molecular and Cellular Cardiology. 145, p. 43-53 11 p.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile22 Citations (Scopus)13 Downloads (Pure)