Projects per year
Personal profile
Academic Background
I am a scientific group leader working with pluripotent stem cells at Norwich Medical School, University of East Anglia, UK. I completed my PhD at the University of Birmingham with a focus on mesenchymal stem cells and the extracellular matrix. I then undertook post-doctoral training at the University of Nottingham developing automated manufacture technologies for human pluripotent stem cells. I was later appointed as a senior research fellow, using CRISPR gene editing and hiPSCs as tools to investigate cardiovascular disease, before setting up my own group at UEA in 2019
Website: https://www.smithlabuea.com/
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Collaborations and top research areas from the last five years
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Dupuytren’s Disease: Harnessing cutting-edge technologies to understand how genetic variants lead to clinically relevant changes in cellular phenotype.
Davidson, R. (Principal Investigator), Clark, I. (Co-Investigator), Pecheva, M. (Co-Investigator), Smith, J. (Co-Investigator) & Warren, D. (Co-Investigator)
Action Arthritis (Norwich Hip Trust)
1/02/26 → 31/01/29
Project: Research
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Identifying novel SNORD116 targets and signalling pathways
Smith, J. (Principal Investigator)
Foundation for Prader-Willi Research
1/03/25 → 28/02/27
Project: Research
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Do snoRNAs govern genotype-phenotype interactions in hypertrophic cardiomyopathy?
Smith, J. (Principal Investigator) & Vassiliou, V. (Co-Investigator)
1/06/23 → 31/05/27
Project: Research
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Investigating cardiomyocyte communication in hypertrophic cardiomyopathy
Smith, J. (Principal Investigator)
1/03/20 → 1/09/22
Project: Research
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Myocardial inflammation after elective percutaneous coronary intervention
Merinopoulos, I., Bhalraam, U., Kasmai, B., Hewson, D., Greenwood, R., Eccleshall, S. C., Smith, J., Tsampasian, V. & Vassiliou, V., 1 Jan 2026, In: Hellenic Journal of Cardiology. 87, p. 4-12 9 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
Footprints in the Sno: Investigating the cellular and molecular mechanisms of SNORD116
Holmes, T. L., Chabronova, A., Denning, C., James, V., Peffers, M. J. & Smith, J. G. W., Mar 2025, In: Open Biology. 15, 3, 240371.Research output: Contribution to journal › Review article › peer-review
Open AccessFile1 Citation (Scopus)4 Downloads (Pure) -
Perlecan (HSPG2) promotes structural, contractile, and metabolic development of human cardiomyocytes
Johnson, B. B., Cosson, M.-V., Tsansizi, L. I., Holmes, T. L., Gilmore, T., Hampton, K., Song, O.-R., Vo, N. T. N., Nasir, A., Chabronova, A., Denning, C., Peffers, M. J., Merry, C. L. R., Whitelock, J., Troeberg, L., Rushworth, S. A., Bernardo, A. S. & Smith, J. G. W., 23 Jan 2024, In: Cell Reports. 43, 1, 113668.Research output: Contribution to journal › Article › peer-review
Open AccessFile21 Citations (Scopus)60 Downloads (Pure) -
SnoRNAs in cardiovascular development, function, and disease
Chabronova, A., Holmes, T. L., Hoang, D. M., Denning, C., James, V., Smith, J. G. W. & Peffers, M. J., Jun 2024, In: Trends in Molecular Medicine. 30, 6, p. 562-578 17 p.Research output: Contribution to journal › Review article › peer-review
Open Access21 Citations (Scopus) -
Circulating intermediate monocytes CD14++CD16+ are increased after elective percutaneous coronary intervention
Merinopoulos, I., Bhalraam, U., Holmes, T., Tsampasian, V., Corballis, N., Gunawardena, T., Sawh, C., Maart, C., Wistow, T., Ryding, A., Eccleshall, S. C., Smith, J. & Vassiliou, V. S., 14 Dec 2023, In: PLoS One. 18, 12, e0294746.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)10 Downloads (Pure)