Collaborations and top research areas from the last five years
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Spectroscopic and synthetic facilities for supramolecular and macromolecular systems
Le Brun, N. (Principal Investigator), Beekman, A. (Co-Investigator), Bidula, S. (Co-Investigator), Bradley, J. (Co-Investigator), Butt, J. (Co-Investigator), Cammidge, A. (Co-Investigator), Cheesman, M. (Co-Investigator), Crack, J. (Co-Investigator), Delso, I. (Co-Investigator), Ganesan, A. (Co-Investigator), Gates, A. (Co-Investigator), Hamilton, C. (Co-Investigator), Sachdeva, A. (Co-Investigator), Searcey, M. (Co-Investigator) & Wallace, M. (Co-Investigator)
Engineering and Physical Sciences Research Council
1/01/25 → 30/06/26
Project: Research
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Native mass spectrometry of proteins, proteins complexes, and protein cofactors at UEA
Crack, J. (Principal Investigator) & Le Brun, N. (Co-Investigator)
British Mass Spectrometry Society
1/08/22 → 31/08/22
Project: Research
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Iron-sulfur cluster-containing sensor regulators: mechanistic and structural studies of DNA-binding
Le Brun, N. (Principal Investigator) & Crack, J. (Co-Investigator)
Biotechnology and Biological Sciences Research Council
1/01/22 → 31/12/24
Project: Research
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Structural and mechanistic insights into NO sensing by iron-sulfur cluster regulators
Le Brun, N. (Principal Investigator) & Crack, J. (Co-Investigator)
Biotechnology and Biological Sciences Research Council
30/05/17 → 29/09/20
Project: Research
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A new pathway for iron-sulphur cluster repair
Le Brun, N. (Principal Investigator), Crack, J. (Co-Investigator), Thomson, A. (Co-Investigator) & Cull, N. (Technician)
Biotechnology and Biological Sciences Research Council
30/05/14 → 29/05/17
Project: Research
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Yeast [FeFe]-hydrogenase-like protein Nar1 binds a [2Fe-2S] cluster
Braymer, J., Knauer, L., Crack, J., Oltmanns, J., Heghmanns, M., Soares, J., Le Brun, N., Schunemann, V. & Kasanmascheff, M., 21 Jan 2026, In: Chemical Science. 17, 1, p. 373-380 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Downloads (Pure) -
ArnR binds a [4Fe-4S] cluster and indirectly senses anaerobicity in Corynebacteria
Crack, J. C., Harvey, L. R., Johnson, K. E. & Le Brun, N. E., Aug 2025, In: Metallomics. 17, 8, mfaf026.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)10 Downloads (Pure) -
Cluster occupancy- and oxidation state-dependence of Yersinia enterocolitica IscR DNA binding
Gray, E., Gao, M., Bradley, J., Crack, J. C. & Le Brun, N. E., Nov 2025, In: Journal of Inorganic Biochemistry. 272, 113011.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)1 Downloads (Pure) -
Synergy of native mass spectrometry and other biophysical techniques in studies of iron sulfur cluster proteins and their assembly
Crack, J. C. & Le Brun, N. E., Jan 2025, In: Biochimica Et Biophysica Acta-Molecular Cell Research. 1872, 1, 119865.Research output: Contribution to journal › Review article › peer-review
Open AccessFile1 Citation (Scopus)13 Downloads (Pure) -
Binding of a single nitric oxide molecule is sufficient to disrupt DNA binding of the nitrosative stress regulator NsrR
Crack, J. C. & Le Brun, N., 7 Dec 2024, In: Chemical Science. 15, 45, p. 18920-18932 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)19 Downloads (Pure)
Datasets
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Liquid-Chromatography Mass Spectrometry Describes Post-Translational Modification of Shewanella Outer Membrane Proteins
Butt, J. (Creator), van Wonderen, J. (Creator) & Crack, J. (Creator), University of East Anglia, 2023
Dataset
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