Justin Bradley

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2.24 Chemistry

Mechanistic studies of mitochondrial ferritin, a key player in iron mediated oxidative stress response and cellular iron metabolism
Le Brun, N., Bradley, J., Hemmings, A. & Moore, G.
Biotechnology and Biological Sciences Research Council
1/10/17 → 30/09/20
Project: Research

26 Article
2 Review article

The ferroxidase centre of Escherichia coli bacterioferritin plays a key role in the reductive mobilisation of the mineral iron core
Bradley, J. M., Bugg, Z., Sackey, A., Andrews, S. C., Wilson, M. T., Svistunenko, D. A., Moore, G. R. & Le Brun, N. E., 15 Apr 2024, In: Angewandte Chemie-International Edition. 63, 16, e202401379.
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Protein encapsulation within the internal cavity of a bacterioferritin
Bradley, J. M., Gray, E., Richardson, J., Moore, G. R. & Le Brun, N. E., 14 Sep 2022, In: Nanoscale. 14, 34, p. 12322-12331 10 p.
Research output: Contribution to journal › Article › peer-review

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4 Citations (Scopus)

16 Downloads (Pure)
Purification and characterization of the isoprene monooxygenase from Rhodococcus sp. strain AD45
Sims, L. P., Lockwood, C. W. J., Crombie, A. T., Bradley, J. M., Le Brun, N. E. & Murrell, J. C., 12 Apr 2022, In: Applied and Environmental Microbiology. 88, 7, e00029-22.
Research output: Contribution to journal › Article › peer-review

Open Access
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6 Citations (Scopus)

14 Downloads (Pure)
Reaction of thiosulfate dehydrogenase with a substrate mimic induces dissociation of the cysteine heme ligand giving insight into the mechanism of oxidative catalysis
Jenner, L. P., Crack, J. C., Kurth, J. M., Soldánová, Z., Brandt, L., Sokol, K. P., Reisner, E., Bradley, J. M., Dahl, C., Cheesman, M. R. & Butt, J. N., 12 Oct 2022, In: Journal of the American Chemical Society. 144, 40, p. 18296–18304 9 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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4 Citations (Scopus)

13 Downloads (Pure)
Second coordination sphere effects on the mechanistic pathways for dioxygen activation by a ferritin: involvement of a Tyr radical and the identification of a cation binding site
Yeh, C-C. G., Mokkawes, T., Bradley, J. M., Le Brun, N. E. & de Visser, S. P., 5 Jul 2022, In: ChemBioChem. 23, 13, e202200257.
Research output: Contribution to journal › Article › peer-review

Open Access
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11 Citations (Scopus)

14 Downloads (Pure)

Justin Bradley

Collaborations and top research areas from the last five years

Dive into details

Mechanistic studies of mitochondrial ferritin, a key player in iron mediated oxidative stress response and cellular iron metabolism

The ferroxidase centre of Escherichia coli bacterioferritin plays a key role in the reductive mobilisation of the mineral iron core

Protein encapsulation within the internal cavity of a bacterioferritin

Purification and characterization of the isoprene monooxygenase from Rhodococcus sp. strain AD45

Reaction of thiosulfate dehydrogenase with a substrate mimic induces dissociation of the cysteine heme ligand giving insight into the mechanism of oxidative catalysis

Second coordination sphere effects on the mechanistic pathways for dioxygen activation by a ferritin: involvement of a Tyr radical and the identification of a cation binding site

Justin Bradley

Collaborations and top research areas from the last five years

Projects

Mechanistic studies of mitochondrial ferritin, a key player in iron mediated oxidative stress response and cellular iron metabolism

Research output

The ferroxidase centre of Escherichia coli bacterioferritin plays a key role in the reductive mobilisation of the mineral iron core

Protein encapsulation within the internal cavity of a bacterioferritin

Purification and characterization of the isoprene monooxygenase from Rhodococcus sp. strain AD45

Reaction of thiosulfate dehydrogenase with a substrate mimic induces dissociation of the cysteine heme ligand giving insight into the mechanism of oxidative catalysis

Second coordination sphere effects on the mechanistic pathways for dioxygen activation by a ferritin: involvement of a Tyr radical and the identification of a cation binding site