Projects per year
Personal profile
Academic Background
I studied medicine at Guy's and St Thomas' Hospitals Medical School, London. I trained as a junior doctor in London, Kent and South Africa before specialist training in haematology in Cambridge and Norwich. I undertook my PhD at the University of Cambridge, studying haematopoietic stem cell self renewal. I have been a Consultant Haematologist at the Norfolk and Norwich University Hospital since 2006 and Professor of Haematology at Norwich Medical School since 2013.
For more information see www.rushworthlab.com
Collaborations and top research areas from the last five years
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Investigation of mitochondrial fate in normal and malignant haematopoiesis.
Rushworth, S., Bowles, K., Croft, A. & Croft, A.
1/03/21 → 31/08/24
Project: Research
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Role of the aging bone marrow in the initiation and proliferation of acute myeloid leukaemia
1/10/19 → 30/09/22
Project: Research
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Studentship/Collaboration with UCAM for Charlotte Hellmich
Bowles, K., Hellmich, C., Rushworth, S. & Watson, A.
1/10/19 → 29/03/23
Project: Research
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Acute myeloid leukemia driven IL-3-dependent upregulation of BCL2 in non-malignant hematopoietic stem and progenitor cells increases venetoclax-induced cytopenias
Fowler-Shorten, D. J., Maynard, R. S., Hampton, K., Altera, A., Markham, M., Ehikioya, M., Wojtowicz, E. E., Bowles, K. M., Rushworth, S. A. & Hellmich, C., May 2024, In: Haematologica. 109, 5, p. 1576-1581 6 p.Research output: Contribution to journal › Letter › peer-review
Open Access -
HSC-derived fatty acid oxidation in steady-state and stressed hematopoiesis
Mistry, J. J., Bowles, K. & Rushworth, S. A., Jan 2023, In: Experimental Hematology. 117, p. 1-8 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
p16INK4A-dependent senescence in the bone marrow niche drives age-related metabolic changes of hematopoietic progenitors
Hellmich, C., Wojtowicz, E., Moore, J. A., Mistry, J. J., Jibril, A., Johnson, B. B., Smith, J. G. W., Beraza, N., Bowles, K. M. & Rushworth, S. A., 24 Jan 2023, In: Blood Advances. 7, 2, p. 256-268 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Panhematopoietic RNA barcoding enables kinetic measurements of nucleate and anucleate lineages and the activation of myeloid clones following acute platelet depletion
Wojtowicz, E. E., Mistry, J. J., Uzun, V., Hellmich, C., Scoones, A., Chin, D. W., Kettyle, L. M., Grasso, F., Lord, A. M., Wright, D. J., Etherington, G. J., Woll, P. S., Belderbos, M. E., Bowles, K. M., Nerlov, C., Haerty, W., Bystrykh, L. V., Jacobsen, S. E. W., Rushworth, S. A. & Macaulay, I. C., 27 Jun 2023, In: Genome Biology. 24, 152.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Plasma cell derived mtDAMPs activate macrophage STING pathway which promotes myeloma progression
Jibril, A., Hellmich, C., Wojtowicz, E. E., Hampton, K., Maynard, R., De Silva, R., Fowler-Shorten, D. J., Mistry, J. J., Moore, J. A., Bowles, K. M. & Rushworth, S. A., 22 Jun 2023, In: Blood. 141, 25, p. 3065–3077 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile