Projects per year
Click here for current PhD opportunities in PHA. But feel free to email me to discuss projects outside these areas and alternative sources of funding.
László obtained his first degree in Chemistry from the Eötvös Loránd University in Budapest. He joined the crystallography group at the Chemical Research Centre of the Hungarian Academy of Science to pursue a doctoral degree. After completing his PhD in 2000, he remained with the same group as a post-doctoral scientist. He moved to the Cambridge Crystallographic Data Centre in 2006 to work on the design of cocrystals. This work was part of a large collaborative project, the Pfizer Institute for Pharmaceutical Materials Science. He continued his research on pharmaceutical cocrystals at University College Cork before joining UEA in 2011.
László’s main research area is the solid state chemistry of pharmaceutical compounds. Drugs can have several solid forms, which have different properties. Current projects focus on predicting what solid forms a particular drug can form, on the design of new multi-component forms (cocrystals, salts, solvates) and on understanding how molecular and structural characteristics influence the properties of solid materials.
A model for a solvent-free synthetic organic research laboratory: click-mechanosynthesis and structural characterization of thioureas without bulk solvents
Vjekoslav Štrukil, Marina D. Igrc, László Fábián, Mirjana Eckert-Maksić, Scott L. Childs, David G. Reid, Melinda J. Duer, Ivan Halasz, Cristina Mottillo and Tomislav Friščić
Green Chem., 2012,14, 2462-2473
Tunable recognition of the steroid α-face by adjacent π-electron density.
T. Friščić, R.W. Lancaster, L. Fábián and P.G. Karamertzanis
Proc. Natl. Acad. Sci. USA, 2010, 107, 13216-13221.
Improving Mechanical Properties of Crystalline Solids by Cocrystal Formation: New Compressible Forms of Paracetamol.
S. Karki, T. Friščić, L. Fábián, P.R. Laity, G.M. Day, W. Jones
Adv. Mater., 2009, 21, 3905-3909.
Cambridge Structural Database Analysis of Molecular Complementarity in Cocrystals.
Cryst. Growth. Des., 2009, 9, 1436-1443.
Organic crystal hydrates: what are the important factors for formation.
L. Infantes, L. Fábián, W.D.S. Motherwell
CrystEngComm, 2007, 9, 65-71.
- Co-editor of Acta Crystallographica, Section E
- Regular refereeing for CrystEngComm, Crystal Growth & Design, Journal of Chemical Research
- Member of the British Crystallographic Association
- Member of the American Chemical Society
- 22nd European Crystallographic Meeting, Budapest, Hungary, 2002
- Hungarian Chemical Society, Balatonszemes, Hungary, 2013
- 27th European Crystallographic Meeting, Bergen, Norway, 2012
- 26th European Crystallographic Meeting, Darmstadt, Germany, 2010
- IQPC Pharmaceutical Co-crystals, Amsterdam, 2008 and 2009
- 237th American Chemical Society National Meeting and Exposition, Salt Lake City, 2009
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Lettice, F., Alexander, M., Askounis, A., Baker, A., Cammidge, A., Chao, Y., Fabian, L., Fielden, J., Hernaez Saenz De Zaitigui, M., Hui, O., Kaplani, E., Khimyak, Y., Liss, P., Lord, R., Marin, M. J., Mayes, A., Melendi-Espina, S., Nolte, S., Romanov, A., Saeed, A., Sobolewski, A., Tolhurst, T. & Wright, J.
6/11/20 → 5/05/22
15/11/18 → 14/11/21
Innovative MulticOmponent Drug dEsign (IMODE) for enhancing regional strategic advantages in pharmaceutical and biomedical applications
1/07/16 → 30/06/21
1/01/14 → 31/12/16
Chemoenzymatic synthesis of fluorinated cellodextrins identifies a new allomorph for cellulose‐like materialsde Andrade, P., Muñoz-García, J. C., Pergolizzi, G., Gabrielli, V., Nepogodiev, S., Iuga, D., Fabian, L., Nigmatullin, R., Johns, M. A., Harniman, R., Eichhorn, S. J., Angulo Alvarez, J., Khimyak, Y. & Field, R. A., 18 Jan 2021, In : Chemistry - A European Journal. 27, 4, p. 1374-1382 9 p.
Research output: Contribution to journal › ArticleOpen AccessFile4 Citations (Scopus)19 Downloads (Pure)
Belton, P., Fabian, L., Reading, M. & Qi, S., 26 May 2020, In : ACS Omega. 5, 20, p. 11402–11410 9 p.
Research output: Contribution to journal › ArticleOpen AccessFile1 Citation (Scopus)28 Downloads (Pure)
Munoz, J., Pergolizzi, G., Gabrielli, V., Nepogodiev, S., Iuga, D., Fábián, L., Nigmatullin, R., Johns, M. A., Harniman, R., Eichhorn, S. J., Angulo, J., Khimyak, Y. & Field, R., 13 Jan 2020.
Research output: Working paper › Discussion paperOpen Access
NMR-Enhanced Crystallography Aids Open Metal–Organic Framework Discovery Using Solvent-Free Accelerated AgingO'Keefe, C. A., Mottillo, C., Vainauskas, J., Fabian, L., Friščić, T. & Schurko, R. W., 26 May 2020, In : Chemistry of Materials. 32, 10, p. 4273–4281 9 p.
Research output: Contribution to journal › ArticleOpen AccessFile4 Citations (Scopus)3 Downloads (Pure)
Fábián, L., Karolewicz, B. & Khimyak, Y. Z., 7 Apr 2019, In : CrystEngComm. 21, 13, p. 2180-2192 13 p.
Research output: Contribution to journal › ArticleOpen AccessFile3 Citations (Scopus)10 Downloads (Pure)
Chemoenzymatic synthesis of fluorinated cellodextrins identifies a new allomorph for cellulose‐like materials
Muñoz-García, J. C. (Creator), de Andrade, P. (Contributor), Pergolizzi, G. (Contributor), Gabrielli, V. (Contributor), Nepogodiev, S. (Contributor), Iuga, D. (Contributor), Fabian, L. (Contributor), Nigmatullin, R. (Contributor), Johns, M. A. (Contributor), Harniman, R. (Contributor), Eichhorn, S. J. (Contributor), Angulo, J. (Contributor), Khimyak, Y. (Contributor) & Field, R. A. (Contributor), Wiley-VCH, Weinheim, 30 Sep 2020