Projects per year
Personal profile
Biography
PhD Positions
Click here for current PhD opportunities in PHA. But feel free to email me to discuss projects outside these areas and alternative sources of funding.
László obtained his first degree in Chemistry from the Eötvös Loránd University in Budapest. He joined the crystallography group at the Chemical Research Centre of the Hungarian Academy of Science to pursue a doctoral degree. After completing his PhD in 2000, he remained with the same group as a post-doctoral scientist. He moved to the Cambridge Crystallographic Data Centre in 2006 to work on the design of cocrystals. This work was part of a large collaborative project, the Pfizer Institute for Pharmaceutical Materials Science. He continued his research on pharmaceutical cocrystals at University College Cork before joining UEA in 2011.
László’s main research area is the solid state chemistry of pharmaceutical compounds. Drugs can have several solid forms, which have different properties. Current projects focus on predicting what solid forms a particular drug can form, on the design of new multi-component forms (cocrystals, salts, solvates) and on understanding how molecular and structural characteristics influence the properties of solid materials.
Selected publications
A model for a solvent-free synthetic organic research laboratory: click-mechanosynthesis and structural characterization of thioureas without bulk solvents
Vjekoslav Štrukil, Marina D. Igrc, László Fábián, Mirjana Eckert-Maksić, Scott L. Childs, David G. Reid, Melinda J. Duer, Ivan Halasz, Cristina Mottillo and Tomislav Friščić
Green Chem., 2012,14, 2462-2473
DOI: 10.1039/C2GC35799B
Tunable recognition of the steroid α-face by adjacent π-electron density.
T. Friščić, R.W. Lancaster, L. Fábián and P.G. Karamertzanis
Proc. Natl. Acad. Sci. USA, 2010, 107, 13216-13221.
DOI: 10.1073/pnas.0915142107
Improving Mechanical Properties of Crystalline Solids by Cocrystal Formation: New Compressible Forms of Paracetamol.
S. Karki, T. Friščić, L. Fábián, P.R. Laity, G.M. Day, W. Jones
Adv. Mater., 2009, 21, 3905-3909.
DOI: 10.1002/adma.200900533
Cambridge Structural Database Analysis of Molecular Complementarity in Cocrystals.
L. Fábián
Cryst. Growth. Des., 2009, 9, 1436-1443.
DOI: 10.1021/cg800861m
Organic crystal hydrates: what are the important factors for formation.
L. Infantes, L. Fábián, W.D.S. Motherwell
CrystEngComm, 2007, 9, 65-71.
DOI: 10.1039/B612529H
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 5 Finished
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The milling of mustard seed into flour - Understanding the particle size changes that occur during the milling process and how this affects the end product quality characteristics
Qi, S. (Principal Investigator) & Fabian, L. (Co-Investigator)
1/04/23 → 30/06/23
Project: Internal Funding › Knowledge Exchange +
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Addressing Interdisciplinary challenges through Raman Microscopy - a new facility for UEA
Lettice, F. (Principal Investigator), Alexander, M. (Co-Investigator), Askounis, A. (Co-Investigator), Baker, A. (Co-Investigator), Cammidge, A. (Co-Investigator), Chao, Y. (Co-Investigator), Fabian, L. (Co-Investigator), Fielden, J. (Co-Investigator), Hernaez, M. (Co-Investigator), Hui, O. (Co-Investigator), Kaplani, E. (Co-Investigator), Khimyak, Y. (Co-Investigator), Liss, P. (Co-Investigator), Lord, R. (Co-Investigator), Marin, M. J. (Co-Investigator), Mayes, A. (Co-Investigator), Melendi-Espina, S. (Co-Investigator), Nolte, S. (Co-Investigator), Romanov, A. (Co-Investigator), Saeed, A. (Co-Investigator), Sobolewski, A. (Co-Investigator), Tolhurst, T. (Co-Investigator) & Wright, J. (Co-Investigator)
Engineering and Physical Sciences Research Council
6/11/20 → 31/08/22
Project: Research
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Enhanced single-crystal X-ray diffraction facilities
Bochmann, M. (Principal Investigator), Fabian, L. (Co-Investigator), Fielden, J. (Co-Investigator), Khimyak, Y. (Co-Investigator) & Wright, J. (Co-Investigator)
Engineering and Physical Sciences Research Council
15/11/18 → 14/11/21
Project: Research
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Innovative MulticOmponent Drug dEsign (IMODE) for enhancing regional strategic advantages in pharmaceutical and biomedical applications
Affouard, F. (Principal Investigator), Qi, S. (Principal Investigator), Alexander, M. (Co-Investigator), Craig, D. (Co-Investigator), Douroumis, D. (Co-Investigator), Fabian, L. (Co-Investigator), Gonnissen, Y. (Co-Investigator), John, I. (Co-Investigator), Mayes, A. (Co-Investigator), Sharma, P. (Co-Investigator) & Siepmann, J. (Co-Investigator)
European Regional Development Fund
1/07/16 → 30/06/21
Project: Research
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PhD Studentship
Fabian, L. (Principal Investigator)
Cambridge Crystallographic Data Centre (CCDC) (The)
1/01/14 → 31/12/16
Project: Research
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Unveiling Solvent-Mediated Mechanochemical Cocrystallization Pathways by In Situ CLASSIC NMR Spectroscopy
Golkowska, A. M., Nowak, M., Fábián, L., Iuga, D., Emmerling, F., Nartowski, K. P., Karolewicz, B. & Khimyak, Y. Z., 27 Apr 2026, In: Molecular Pharmaceutics. 23, 6, p. 3309-3327 19 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Novel multicomponent crystal forms of artesunate
Madu, S. J., Wang, K., Fábián, L. & Li, M., 28 Nov 2025, In: CrystEngComm. 27, 44, p. 7146-7169 24 p.Research output: Contribution to journal › Article › peer-review
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Probing assembly/disassembly of ordered molecular hydrogels
Ramalhete, S. M., Nartowski, K. P., Green, H., Angulo, J., Iuga, D., Fábián, L., Lloyd, G. O. & Khimyak, Y. Z., 1 Jan 2025, In: Faraday Discussions. 255, p. 495-519 25 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile28 Downloads (Pure) -
Directing crystallization outcomes of conformationally flexible molecules: polymorphs, solvates and desolvation pathways of fluconazole
Nowak, M., Dyba, A., Janczak, J., Morritt, A., Fabian, L., Karolewicz, B., Khimyak, Y. Z., Braun, D. E. & Nartowski, K. P., 7 Feb 2022, In: Molecular Pharmaceutics. 19, 2, p. 456-471 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile29 Citations (Scopus)44 Downloads (Pure) -
Self-assembling, supramolecular chemistry and pharmacology of amphotericin B: Poly-aggregates, oligomers and monomers
Fernández-García, R., Muñoz-García, J. C., Wallace, M., Fabian, L., González-Burgos, E., Gómez-Serranillos, M. P., Raposo, R., Bolás-Fernández, F., Ballesteros, M. P., Healy, A. M., Khimyak, Y. Z. & Serrano, D. R., Jan 2022, In: Journal of Controlled Release. 341, p. 716-732 17 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile49 Citations (Scopus)82 Downloads (Pure)
Datasets
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Chemoenzymatic synthesis of fluorinated cellodextrins identifies a new allomorph for cellulose‐like materials
Muñoz-García, J. C. (Creator), de Andrade, P. (Contributor), Pergolizzi, G. (Contributor), Gabrielli, V. (Contributor), Nepogodiev, S. (Contributor), Iuga, D. (Contributor), Fabian, L. (Contributor), Nigmatullin, R. (Contributor), Johns, M. A. (Contributor), Harniman, R. (Contributor), Eichhorn, S. J. (Contributor), Angulo Alvarez, J. (Contributor), Khimyak, Y. (Contributor) & Field, R. A. (Contributor), Wiley, 30 Sept 2020
Dataset
File
Activities
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Pharma Industry Awards UK (judge)
Fabian, L. (Assessor)
29 Jul 2024 → 18 Sept 2024Activity: Other activity types › Other
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External examiner of MSc programmes in School of Pharmacy (UCL)
Fabian, L. (Examiner)
2024 → 2027Activity: Examination
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National Research, Development and Innovation Office (External organisation)
Fabian, L. (Member)
2024 → 2025Activity: Membership › Committee