Research output per year
Research output per year
- 10 results
Search results
-
2022
Structural basis of the negative allosteric modulation of 5-BDBD at human P2X4 receptors
Bidula, S., Nadzirin, I. B., Cominetti, M., Hickey, H., Cullum, S. A., Searcey, M., Schmid, R. & Fountain, S. J., 1 Jan 2022, In: Molecular Pharmacology. 101, 1, p. 33-44 12 p.Research output: Contribution to journal › Article › peer-review
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2021
Amino DSA analogues as payloads for antibody-drug conjugates with multiple sites for conjugation. Initial studies and solid phase synthesis
M. M. D. Cominetti, M., Goddard, Z. R., Howman, C. E., O'Connell, M. A. & Searcey, M., 25 May 2021, In: Tetrahedron Letters. 72, 153058.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Downloads (Pure) -
Peptide directed phthalocyanine-gold nanoparticles for selective photodynamic therapy of EGFR overexpressing cancers
Goddard, Z. R., Beekman, A. M., Cominetti, M. M. D., O'Connell, M. A., Chambrier, I., Cook, M. J., Marin, M. J., Russell, D. A. & Searcey, M., 1 Feb 2021, In: RSC Medicinal Chemistry. 12, 2, p. 288-292 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)15 Downloads (Pure) -
2020
A peptide-duocarmycin conjugate targeting the Thomsen-Friedenreich antigen has potent and selective antitumour activity
Cartwright, O. C., Beekman, A. M., Cominetti, M. M. D., Russell, D. A. & Searcey, M., 15 Jul 2020, In: Bioconjugate Chemistry. 31, 7, p. 1745–1749 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)1 Downloads (Pure) -
2019
A small molecule drug conjugate (SMDC) of DUPA and a duocarmycin built on the solid phase
Beekman, A., Cominetti, M., Cartwright, O., Boger, D. L. & Searcey, M., Dec 2019, In: MedChemComm. 10, 12, p. 2170-2174 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Downloads (Pure) -
Identification of selective protein-protein interaction inhibitors using efficient in silico peptide-directed ligand design
Beekman, A. M., Cominetti, M. M. D., Walpole, S. J., Prabhu, S., O'Connell, M. A., Angulo Alvarez, J. & Searcey, M., 28 Apr 2019, In: Chemical Science. 10, 16, p. 4502-4508 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)37 Downloads (Pure) -
2017
Cytotoxicity of Pyrazine-Based Cyclometalated (C^Npz^C)Au(III) Carbene Complexes: Impact of the Nature of the Ancillary Ligand on the Biological Properties
Bertrand, B., Fernandez-Cestau, J., Angulo, J., Cominetti, M. M. D., Waller, Z. A. E., Searcey, M., O'Connell, M. A. & Bochmann, M., 15 May 2017, In: Inorganic Chemistry. 56, 10, p. 5728–5740 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile39 Citations (Scopus)19 Downloads (Pure) -
2016
Open-resorcinarenes, a new family of multivalent scaffolds
Cominetti, M. M. D., Hughes, D. L. & Matthews, S. E., 21 Nov 2016, In: Organic & Biomolecular Chemistry. 14, 43, p. 10161-10164Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)10 Downloads (Pure) -
2015
Base-modified NAD and AMP derivatives and their activity against bacterial DNA ligases
Pergolizzi, G., Cominetti, M., Butt, J. N., Field, R. A., Bowater, R. & Wagner, G. K., 2015, In: Organic & Biomolecular Chemistry. 13, p. 6380-6398 19 p.Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus) -
Identification of a new p53/MDM2 inhibitor motif inspired by studies of chlorofusin
Cominetti, M., Goffin, S., Raffel, E., Turner, K., Ramoutar, J., O'Connell, M., Howell, L. & Searcey, M., 1 Nov 2015, In: Bioorganic & Medicinal Chemistry Letters. 25, 21, p. 4878-4880 3 p.Research output: Contribution to journal › Article › peer-review
File15 Citations (Scopus)11 Downloads (Pure)