Projects per year
Personal profile
Biography
Marcus Flather graduated from the Royal Free Hospital School of Medicine, University of London in 1982 and trained in general medicine and cardiology in London and Oxford. In 1988 he joined the Department of Cardiovascular Medicine and the Clinical Trial Service Unit at the University of Oxford as a British Heart Foundation Junior Research Fellow with Peter Sleight, Rory Collins and Richard Peto working on the large scale ISIS trials in acute myocardial infarction.
In 1993 he moved to McMaster University in Hamilton, Canada, to work with Salim Yusuf as a Clinical Research Scholar on international trials in acute coronary syndromes including the OASIS programme, and undertook formal training in clinical trials and epidemiology. In 1996 he took up the post of Director of the new Clinical Trials and Evaluation Unit (CTEU) at the Royal Brompton and Harefield Hospitals where the Unit developed an international reputation in the design and management of randomised trials in cardiovascular and respiratory diseases.
In September 2011 he took up the post of Professor of Medicine and Clinical Trials at the University of East Anglia and Director of Research at the Norfolk and Norwich University Hospitals NHS Foundation Trust in Norwich. Marcus Flather is a Fellow of the Royal College of Physicians (UK) and holds a certificate of higher specialist training in Cardiology and General (Internal) Medicine in the UK (CCST). He has about 200 peer reviewed publications, is a recognised expert in clinical trials and has more than 20 years experience of collaborating with industry partners in drug and device development.
In 1993 he moved to McMaster University in Hamilton, Canada, to work with Salim Yusuf as a Clinical Research Scholar on international trials in acute coronary syndromes including the OASIS programme, and undertook formal training in clinical trials and epidemiology. In 1996 he took up the post of Director of the new Clinical Trials and Evaluation Unit (CTEU) at the Royal Brompton and Harefield Hospitals where the Unit developed an international reputation in the design and management of randomised trials in cardiovascular and respiratory diseases.
In September 2011 he took up the post of Professor of Medicine and Clinical Trials at the University of East Anglia and Director of Research at the Norfolk and Norwich University Hospitals NHS Foundation Trust in Norwich. Marcus Flather is a Fellow of the Royal College of Physicians (UK) and holds a certificate of higher specialist training in Cardiology and General (Internal) Medicine in the UK (CCST). He has about 200 peer reviewed publications, is a recognised expert in clinical trials and has more than 20 years experience of collaborating with industry partners in drug and device development.
Areas of Expertise
General cardiology; clinical trials; acute coronary syndrome (heart attacks and angina).
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Advanced pulmonary flow haemodynamic biomarkers in pulmonary hypertension
Garg, P., Clark, A., Flather, M., Grafton-Clarke, C. & Wilson, A.
1/05/25 → 30/04/28
Project: Research
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Automated 4D flow cardiac MRI pipeline to derive peak mitral inflow diastolic velocities using short-axis cine stack: Two centre validation study against echocardiographic pulse-wave doppler
Assadi, H., Li, R., Grafton-Clarke, C., Uthayachandran, B., Alabed, S., Maiter, A., Archer, G. T., Swoboda, P. P., Sawh, C., Ryding, A., Nelthorpe, F., Kasmai, B., Ricci, F., van der Geest, R. J., Flather, M., Vassiliou, V. S., Swift, A. J. & Garg, P., 16 Jan 2023, In: BMC Cardiovascular Disorders. 23, 24.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)20 Downloads (Pure) -
Mitral regurgitation quantification by cardiac magnetic resonance imaging (MRI) remains reproducible between software solutions
Grafton-Clarke, C., Thornton, G., Fidock, B., Archer, G., Hose, R., van der Geest, R. J., Zhong, L., Swift, A. J., Wild, J. M., De Gárate, E., Bucciarelli-Ducci, C., Plein, S., Treibel, T. A., Flather, M., Vassiliou, V. S. & Garg, P., 10 May 2023, In: Wellcome Open Research. 6, 253.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Downloads (Pure) -
Angiotensin receptor blockers and β blockers in Marfan syndrome: an individual patient data meta-analysis of randomised trials
Pitcher, A., Spata, E., Emberson, J., Davies, K., Halls, H., Holland, L., Wilson, K., Reith, C., Child, A. H., Clayton, T., Dodd, M., Flather, M., Jin, X. Y., Sandor, G., Groenink, M., Mulder, B., de Backer, J., Evangelista, A., Forteza, A., Teixido-Turà, G., & 11 others , 10 Sept 2022, In: The Lancet. 400, 10355, p. 822-831 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile48 Citations (Scopus)21 Downloads (Pure) -
Cardiovascular examination using hand-held cardiac ultrasound
Jenkins, S., Shiha, M. G., Yones, E., Wardley, J., Ryding, A., Sawh, C., Flather, M., Morris, P., Swift, A. J., Vassiliou, V. S. & Garg, P., Mar 2022, In: Journal of Echocardiography. 20, p. 1-9 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (SciVal)56 Downloads (Pure) -
Cost-effectiveness of bilateral vs. single internal thoracic artery grafts at 10 years
Little, M., Gray, A. M., Altman, D. G., Benedetto, U., Flather, M., Gerry, S., Lees, B., Murphy, J., Gaudino, M., Taggart, D. P. & Arterial Revascularization Trial investigators, May 2022, In: European Heart Journal - Quality of Care and Clinical Outcomes. 8, 3, p. 324–332 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)34 Downloads (Pure)