Projects per year
Personal profile
Key Research Interests
I am an experienced biomedical research scientist with a background in Molecular Biology and Nutrition. My research focus to date relates to nutrition in brain health and disease (predominantly from a mechanistic perspective). I am currently interested in elucidating how this is influenced by sex differences (often overlooked in both nutrition and biomedical science). Indeed, my current research projects investigate how sex differences and menopause influence cognitive decline and subseqent Alzheimer’s disease vulnerability. I have expertise in a range of molecular and analytical techniques and experience conducting both preclinical studies and clinical studies.
Teaching Interests
I am lecturer and module organiser for the Applied Physiology, Biochemistry and nutrition module of the dietetics programme.
Collaborations and top research areas from the last five years
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Metabolomic signatures in menopause mediated Alzheimer’s development
1/07/24 → 30/06/25
Project: Research
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Sex, Menopause and spontaneous Alzheimer’s disease
Pontifex, M. G., Muller, M. & Vauzour, D.
1/10/22 → 30/09/24
Project: Research
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Impact of a combination of food bioactives on cognitive performance in a murine model of ageing
Vauzour, D., Muller, M. & Pontifex, M. G.
1/01/21 → 30/06/21
Project: Research
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(Poly)phenol-rich grape and blueberry extract prevents LPS-induced disruption of the blood-brain barrier through the modulation of the gut microbiota-derived uremic toxins
Connell, E., Le Gall, G., McArthur, S., Lang, L., Breeze, B., Pontifex, M. G., Sami, S., Pourtau, L., Gaudout, D., Müller, M. & Vauzour, D., Nov 2024, In: Neurochemistry International. 180, 105878.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Downloads (Pure) -
(Poly)phenols and brain health – beyond their antioxidant capacity
Hunt, T., Pontifex, M. G. & Vauzour, D., Dec 2024, In: FEBS Letters. 598, 24, p. 2949-2962 14 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile20 Downloads (Pure) -
A novel Mediterranean diet-inspired supplement ameliorates cognitive, microbial, and metabolic deficits in a mouse model of low-grade inflammation
Pontifex, M. G., Connell, E., Le Gall, G., Lang, L., Pourtau, L., Gaudout, D., Angeloni, C., Zallocco, L., Ronci, M., Giusti, L., Müller, M. & Vauzour, D., Jun 2024, In: Gut Microbes. 16, 1, 2363011.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Downloads (Pure) -
Cerebrovascular damage caused by the gut microbe/host co-metabolite p-cresol sulfate is prevented by blockade of the EGF receptor
Shah, S. N., Knausenberger, T. B-A., Pontifex, M. G., Connell, E., Le Gall, G., Hardy, T. A. J., Randall, D. W., McCafferty, K., Yaqoob, M. M., Solito, E., Müller, M., Stachulski, A. V., Glen, R. C., Vauzour, D., Hoyles, L. & McArthur, S., 31 Dec 2024, In: Gut Microbes. 16, 1, 2431651.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Downloads (Pure) -
Dietary (poly)phenols and the gut–brain axis in ageing
Láng, L., McArthur, S., Lazar, A. S., Pourtau, L., Gaudout, D., Pontifex, M. G., Müller, M. & Vauzour, D., 16 May 2024, In: Nutrients. 16, 10, 1500.Research output: Contribution to journal › Review article › peer-review
Open AccessFile11 Downloads (Pure)