Projects per year
Personal profile
Areas of Expertise
Multiple Myeloma; drug resistance in cancer; cell adhesion. cell migration, cell death, qRT-PCR (SYBR green and Taqman),Flow cytometry,immunocytochemistry, cell culture, organoid growth.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, ’Metalloproteinase Expression in Bone Marrow-derived Macrophages: Roles in Cell Migration, University of East Anglia
Projects
- 2 Finished
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Understanding mechanisms underpinning primary sclerosing cholangitis: pilot studies of liver biopsy transcriptomics and establishment of an ex-vivo organotypic model (funding for Megan Murray)
Gavrilovic, J., Mogensen, M. & Murray, M.
National Institute for Health and Care Research
27/05/15 → 31/03/16
Project: Research
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Research output
- 13 Article
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Novel specific human and mouse stromelysin-1 (MMP-3) and stromelysin-2 (MMP-10) antibodies for biochemical and immunohistochemical analyses
Mirastschijski, U., Dinesh, N., Baskaran, S., Wedekind, D., Gavrilovic, J., Murray, M. Y., Bevan, D. & Kelm, S., Jul 2019, In: Wound Repair and Regeneration. 27, 4, p. 309-323Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)20 Downloads (Pure) -
Activity of Bruton's tyrosine-kinase inhibitor ibrutinib in patients with CD117-positive acute myeloid leukaemia: a mechanistic study using patient-derived blast cells
Rushworth, S. A., Pillinger, G., Abdul-Aziz, A., Piddock, R., Shafat, M. S., Murray, M. Y., Zaitseva, L., Lawes, M. J., MacEwan, D. J. & Bowles, K. M., 1 May 2015, In: The Lancet Haematology. 2, 5, p. e204-e211 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile22 Citations (Scopus)22 Downloads (Pure) -
Ibrutinib inhibits BTK-driven NF-κB p65 activity to overcome bortezomib-resistance in multiple myeloma
Murray, M. Y., Zaitseva, L., Auger, M. J., Craig, J. I. O., MacEwan, D., Rushworth, S. A. & Bowles, K. M., 18 Jul 2015, In: Cell Cycle. 14, 14, p. 2367-2375 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile47 Citations (Scopus)32 Downloads (Pure) -
Ibrutinib inhibits SDF1/CXCR4 mediated migration in AML
Zaitseva, L., Murray, M. Y., Shafat, M. S., Lawes, M. J., MacEwan, D. J., Bowles, K. M. & Rushworth, S. A., 30 Oct 2014, In: Oncotarget. 5, 20, p. 9930-9938 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile63 Citations (SciVal)25 Downloads (Pure) -
Identification of Bruton's tyrosine kinase as a therapeutic target in acute myeloid leukemia
Rushworth, S. A., Murray, M. Y., Zaitseva, L., Bowles, K. M. & MacEwan, D. J., 20 Feb 2014, In: Blood. 123, 8, p. 1229-1238 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile100 Citations (SciVal)18 Downloads (Pure)