Projects per year
Professor Michael Müller is a Professor of Nutrigenomics and Systems Nutrition. He is a renowned expert in the area of molecular nutrition related to lipid homeostasis, nutrigenomics and nutritional systems biology and his work is focussed on the molecular mechanisms underlying genome-wide effects of foods (specific bioactive components or nutrients) on immuno-metabolic health and plasticity of the gut-liver axis.
Professor Muller is a member of the editorial board of the American Journal of Clinical Nutrition. He was a member of the editorial boards of numerous journals, i.e. “BMC Genomics” (associate editor), "European Journal of Nutrition" (section editor "Nutrigenomics") and “PLOS One” (academic editor). He is an visiting professor at Nanjing Agricultural University (China) and (co)author of more than 250 peer-reviewed publications with more than 16000 citations. As promoter, he has supervised 26 PhD students. He has an H-factor of 75. Since September 2019 he is the scientific director (CEO) of NuGO, an association of Universities and Research Institutes with a focus on joint development of research in molecular nutrition, personalised nutrition, nutrigenomics, and nutritional systems biology.
Visiting professor at Nanjing Agricultural University (China)
Editorial board member of the American Journal of Clinical Nutrition, Review editor “Frontiers in Genomics”
Member of the BBSRC Bioscience for Health Strategy Advisory Panel 2016-2020 (UK)
Member of the MRC Population Health and Systems Medicine Panel 2017-2021 (UK)
Member of the SAB of the TNO-Industry project PhenFlex II 2018-2021 (NL)
Member of the international expert group “UK Nutrition Research Partnership for health and disease” 2018-2021 (UK)
Member of the Scientific Committee of the Fondazione Umberto Veronesi.
Reviewer of articles submitted to Journal of Hepatology, Diabetes, Nature Reviews Genetics, Nature Reviews Gastroenterology, Hepatology, Cancer Research, Faseb Journal, American Journal of Clinical Nutrition.
Reviewer of grant applications submitted to INSERM & ANR (France, also function as rapporteur), NWO (The Netherlands), Swiss National Science Foundation, DFG (Germany), ERC (EU), Qatar Research Foundation and many others.
Associate Editor of “BMC Genomics”,
Section editor "Nutrigenomics” of "European Journal of Nutrition",
Academic editor of “PLOS ONE”
Member of the International Advisory Board of COSBI (The Microsoft Research - University of Trento Centre for Computational and Systems Biology) 2013-2016.
Member of the International Advisory Board of Biopolis S.L. Valencia, Spain.
Key Research Interests and Expertise
Molecular nutrition related to lipid homeostasis, nutrigenomics and nutritional systems biology.
Molecular mechanisms underlying genome-wide effects of foods (specific bioactive components or nutrients) on metabolic health and plasticity.
1983 - 1988 University Freiburg/Germany
PhD thesis project
1979 - 1983 University Freiburg/Germany
Examination as chemist (Diplomchemiker)
1976 - 1979 University Dortmund/Germany
Pre examination chemistry
1988 – 1994 German Cancer Research Center, Division of Tumorbiochemistry, Heidelberg/Germany. Postdoctoral fellow and scientific employee at the German Cancer Research Center.
1994 - Nov 2000 University Hospital Groningen, Division of Gastroenterology and Hepatology, Groningen/The Netherlands. Associate professor, senior scientist and research leader (“Regulation of transport proteins in normal and diseased liver”)
2000 – 2013 University Wageningen, Nutrition, Metabolism and Genomics group, Wageningen/ The Netherlands. Full professor and Chair of Nutrition, Metabolism and Genomics at Wageningen University/The Netherlands. From 2003-2009 he was Scientific Director of the Nutrigenomics Consortium. From 2010-2013 he was Scientific Director of the Netherlands Nutrigenomics Center. He was board member of the NUGO.
2014 – now University of East Anglia Norwich/UK. Full Professor at the Norwich Medical School (Systems Nutrition and Nutrigenomics).
2014 - 2019 Director of the Food and Health Alliance (Norwich Research Park).
Sept 2019 - Scientific director (CEO) of NuGO.
Doctor rerum naturalium, University of Freiburg
Award Date: 1 Jan 1989
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The impact of Cranberries on the gut microbiota and cognition in “at-genetic-risk” Alzheimer’s disease participants: a double blind, randomised placebo controlled, parallel group study.
1/09/17 → 30/06/22
1/01/21 → 30/06/21
1/08/15 → 31/07/16
Anthocyanins promote learning through modulation of synaptic plasticity related proteins in an animal model of ageingVauzour, D., Rendeiro, C., D'Amato, A., Waffo-Téguo, P., Richard, T., Mérillon, J. M., Pontifex, M. G., Connell, E., Müller, M., Butler, L. T., Williams, C. M. & Spencer, J. P. E., 31 Jul 2021, In : Antioxidants. 10, 8, 1235.
Research output: Contribution to journal › ArticleOpen AccessFile1 Downloads (Pure)
APOE4 genotype exacerbates the impact of menopause on cognition and synaptic plasticity in APOE‐TR micePontifex, M. G., Martinsen, A., Saleh, R. N. M., Harden, G., Tejera, N., Müller, M., Fox, C., Vauzour, D. & Minihane, AM., May 2021, In : The FASEB Journal. 35, 5, e21583.
Research output: Contribution to journal › ArticleOpen AccessFile11 Downloads (Pure)
Pontifex, M. G., Malik, M. M. A. H., Connell, E., Müller, M. & Vauzour, D., 19 Feb 2021, In : Frontiers in Neuroscience. 15, 640648.
Research output: Contribution to journal › Review articleOpen AccessFile3 Citations (Scopus)10 Downloads (Pure)
(-)-Epicatechin and NADPH oxidase inhibitors prevent bile acid-induced Caco-2 monolayer permeabilization through ERK1/2 modulationWang, Z., Litterio, M. C., Müller, M., Vauzour, D. & Oteiza, P. I., Jan 2020, In : Redox Biology. 28, 101360.
Research output: Contribution to journal › ArticleOpen AccessFile9 Citations (Scopus)33 Downloads (Pure)
(-)-Epicatechin Prevents High Fat Diet-Induced Bile-Associated Intestinal Permeabilization Both In Vivo and In VitroWang, Z., Litterio, C., Muller, M., Vauzour, D. & Oteiza, P., 1 Jun 2020, p. 487. 1 p.
Research output: Contribution to conference › AbstractOpen Access