Penny Powell

Search results

• 2021

  Enhanced small neutral but not branched chain amino acid transport after epigenetic sodium coupled neutral amino acid transporter‐2 (SNAT2) cDNA expression in myoblasts

  Pearson, T., Wendowski, O. & Powell, P. P., Jun 2021, In: Journal of Cachexia, Sarcopenia and Muscle. 12, 3, p. 811-822 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  2 Citations (Scopus)

  18 Downloads (Pure)

• Non‐canonical autophagy functions of ATG16L1 in epithelial cells limit lethal infection by influenza A virus

  Wang, Y., Sharma, P., Jefferson, M., Zhang, W., Bone, B., Kipar, A., Bitto, D., Coombes, J. L., Pearson, T., Man, A., Zhekova, A., Bao, Y., Tripp, R. A., Carding, S. R., Yamauchi, Y., Mayer, U., Powell, P. P., Stewart, J. P. & Wileman, T., 15 Mar 2021, In: The EMBO Journal. 40, 6, e105543.

  Research output: Contribution to journal › Article › peer-review

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  38 Citations (Scopus)

  39 Downloads (Pure)
• 2020

  Regulation of cytokine signaling through direct interaction between cytokine receptors and the ATG16L1 WD40 domain

  Serramito-Gómez, I., Boada-Romero, E., Villamuera, R., Fernández-Cabrera, Á., Cedillo, J. L., Martín-Regalado, Á., Carding, S., Mayer, U., Powell, P. P., Wileman, T., García-Higuera, I. & Pimentel-Muiños, F. X., 20 Nov 2020, In: Nature Communications. 11, 1, 5919 .

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  10 Citations (Scopus)

  25 Downloads (Pure)

• Regulatory network analysis of Paneth cell and goblet cell enriched gut organoids using transcriptomics approaches

  Treveil, A., Sudhakar, P., Matthews, Z. J., Wrzesiński, T., Jones, E. J., Brooks, J., Ölbei, M., Hautefort, I., Hall, L. J., Carding, S. R., Mayer, U., Powell, P. P., Wileman, T., Di Palma, F., Haerty, W. & Korcsmáros, T., 1 Feb 2020, In: Molecular Omics. 16, 1, p. 39-58 20 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  29 Citations (Scopus)

  22 Downloads (Pure)
• 2019

  Integrative analysis of Paneth cell proteomic and transcriptomic data from intestinal organoids reveals functional processes dependent on autophagy

  Jones, E. J., Matthews, Z. J., Gul, L., Sudhakar, P., Treveil, A., Divekar, D., Buck, J., Wrzesinski, T., Jefferson, M., Armstrong, S. D., Hall, L. J., Watson, A. J. M., Carding, S. R., Haerty, W., Di Palma, F., Mayer, U., Powell, P. P., Hautefort, I., Wileman, T. & Korcsmaros, T., 18 Mar 2019, In: Disease Models & Mechanisms. 12, 3, dmm037069.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  19 Citations (Scopus)

  42 Downloads (Pure)

• The ATG5-binding and coiled coil domains of ATG16L1 maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3 associated phagocytosis

  Rai, S., Arasteh, J., Jefferson, M., Pearson, T., Wang, Y., Zhang, W., Bicsak, B., Divekar, D., Powell, P., Naumann, R., Beraza, N., Carding, S., Florey, O., Mayer, U. & Wileman, T., 3 Apr 2019, In: Autophagy. 15, 4, p. 599-612 14 p.

  Research output: Contribution to journal › Article › peer-review

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  67 Citations (Scopus)

  46 Downloads (Pure)

• The autophagy protein ATG16L1 is required for Sindbis virus-induced eIF2α phosphorylation and stress granule formation

  Jefferson, M., Bone, B., Buck, J. L. & Powell, P. P., 29 Dec 2019, In: Viruses-Basel. 12, 1, 39.

  Research output: Contribution to journal › Article › peer-review

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  9 Citations (Scopus)

  29 Downloads (Pure)
• 2018

  Proteomic profiling of enteroid cultures skewed towards development of specific epithelial lineages

  Luu, L., Matthews, Z. J., Armstrong, S. D., Powell, P., Wileman, T., Wastling, J. M. & Coombes, J. L., Aug 2018, In: Proteomics. 18, 16, 1800132.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  8 Citations (Scopus)

  45 Downloads (Pure)
• 2015

  Extracts of feijoa inhibit toll-like receptor 2 signaling and activate autophagy implicating a role in dietary control of IBD

  Nasef, N. A., Mehta, S., Powell, P., Marlow, G., Wileman, T. & Ferguson, L. R., 25 Jun 2015, In: PLoS One. 10, 6, e0130910.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  11 Citations (Scopus)

  21 Downloads (Pure)
• 2014

  Host factors interacting with the pestivirus N erminal protease, Npro are components of the ribonucleoprotein complex

  Jefferson, M., Donaszi-Ivanov, A., Pollen, S., Dalmay, T., Saalbach, G. & Powell, P. P., Sep 2014, In: Journal of Virology. 88, 18, p. 10340-10353 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  22 Citations (Scopus)

  22 Downloads (Pure)

• The pestivirus N terminal protease N(pro) redistributes to mitochondria and peroxisomes suggesting new sites for regulation of IRF3 by N(pro.)

  Jefferson, M., Whelband, M., Mohorianu, I. & Powell, P. P., 14 Feb 2014, In: PLoS One. 9, 2, e88838.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  21 Citations (Scopus)

  19 Downloads (Pure)
• 2013

  Autophagy and formation of tubulovesicular autophagosomes provide a barrier against nonviral gene delivery

  Roberts, R., Al-Jamal, W., Whelband, M., Thomas, P., Jefferson, M., van den Bossche, J., Powell, P. P., Kostarelos, K. & Wileman, T., May 2013, In: Autophagy. 9, 5, p. 667-682 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  50 Citations (Scopus)

  17 Downloads (Pure)

• Foot-and-mouth disease virus 3C protease induces fragmentation of the Golgi compartment and blocks intra-Golgi transport

  Zhou, Z., Mogensen, M. M., Powell, P. P., Curry, S. & Wileman, T., Nov 2013, In: Journal of Virology. 87, 21, p. 11721-11729 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  34 Citations (Scopus)

  21 Downloads (Pure)

• Small RNA analysis in Sindbis virus infected human HEK293 cells

  Donaszi-Ivanov, A., Mohorianu, I., Dalmay, T. & Powell, P. P., 31 Dec 2013, In: PLoS One. 8, 12, e84070.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  12 Citations (Scopus)

  19 Downloads (Pure)

• The microtubule end-binding protein EB2 is a central regulator of microtubule reorganisation in apico-basal epithelial differentiation

  Goldspink, D., Gadsby, J., Bellett, G., Keynton, J., Tyrrell, B., Lund, E., Powell, P., Thomas, P. & Mogensen, M., 1 Sep 2013, In: Journal of Cell Science. 126, Pt 17, p. 4000-4014 15 p.

  Research output: Contribution to journal › Article › peer-review
  37 Citations (Scopus)
• 2010

  Effectiveness of common household cleaning agents in reducing the viability of human influenza A/H1N1

  Greatorex, J. S., Page, R. F., Curran, M. D., Digard, P., Enstone, J. E., Wreghitt, T., Powell, P., Sexton, D., Vivancos, R. & Nguyen-Van-Tam, J. S., 1 Feb 2010, In: PLoS One. 5, 2, e8987.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  35 Citations (Scopus)

  22 Downloads (Pure)
• 2008

  The Npro product of classical swine fever virus interacts with IkappaBalpha, the NF-kappaB inhibitor

  Doceul, V., Charleston, B., Crooke, H., Reid, E., Powell, P. & Seago, J., Aug 2008, In: Journal of General Virology. 89, 8, p. 1881-1889 9 p.

  Research output: Contribution to journal › Article › peer-review
  49 Citations (Scopus)
• 2007

  Regulation of porcine classical and nonclassical MHC class I expression

  Tennant, L. M., Renard, C., Chardon, P. & Powell, P. P., May 2007, In: Immunogenetics. 59, 5, p. 377-89 13 p.

  Research output: Contribution to journal › Article › peer-review
  23 Citations (Scopus)

• Regulation of porcine classical and non classical MHC class I expression

  Tennant, L. M., Renard, C., Chardon, P. & Powell, P. P., May 2007, In: Immunogenetics. 59, 5, p. 377-389 13 p.

  Research output: Contribution to journal › Article
• 2005

  Loss of interferon regulatory factor 3 in cells infected with classical swine fever virus involves the N-terminal protease, Npro

  La Rocca, S. A., Herbert, R. J., Crooke, H., Drew, T. W., Wileman, T. E. & Powell, P. P., 2005, In: Journal of Virology. 79, 11, p. 7239-7247 9 p.

  Research output: Contribution to journal › Article
  101 Citations (Scopus)
• 2004

  Classical swine fever virus induces proinflammatory cytokines and tissue factor expression and inhibits apoptosis and interferon synthesis during the establishment of long-term infection of porcine vascular endothelial cells

  Bensaude, E., Turner, J. L. E., Wakeley, P. R., Sweetman, D. A., Pardieu, C., Drew, T. W., Wileman, T. & Powell, P. P., 2004, In: Journal of General Virology. 85, 4, p. 1029-1037 9 p.

  Research output: Contribution to journal › Article
  107 Citations (Scopus)
• 2001

  African swine fever virus infection of procine aortic endothelial cells leads to inhibition of inflammatory responses, activation of the thrombotic state and apoptosis

  Vallee, I., Tait, S. W. G. & Powell, P. P., 2001, In: Journal of Virology. 75, 21, p. 10372-10382 11 p.

  Research output: Contribution to journal › Article
  50 Citations (Scopus)
• 2000

  Mechanism of inactivation of NF-κB by a viral homologue of IκBα. Signal-induced release of IκBα results in binding of the viral homologue to NF-κB

  Tait, S. W. G., Reid, E. B., Greaves, D. R., Wileman, T. E. & Powell, P. P., 3 Nov 2000, In: Journal of Biological Chemistry. 275, 44, p. 34656-34664 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  82 Citations (Scopus)
• 1998

  African swine fever: A disease characterized by apoptosis

  Oura, C. A. L., Powell, P. P. & Parkhouse, R. M. E., 1 Jun 1998, In: Journal of General Virology. 79, 6, p. 1427-1438 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  73 Citations (Scopus)

• Detection of African swine fever virus in infected pig tissues by immunocytochemistry and in situ hybridisation

  Oura, C. A. L., Powell, P. P. & Parkhouse, R. M. E., Jun 1998, In: Journal of Virological Methods. 72, 2, p. 205-217 13 p.

  Research output: Contribution to journal › Article › peer-review
  31 Citations (Scopus)

• The pathogenesis of African swine fever in the resistant bushpig

  Oura, C. A. L., Powell, P. P., Anderson, E. & Parkhouse, R. M. E., 1 Jun 1998, In: Journal of General Virology. 79, 6, p. 1439-1443 5 p.

  Research output: Contribution to journal › Article › peer-review
  75 Citations (Scopus)
• 1996

  An IκB homolog encoded by African swine fever virus provides a novel mechanism for downregulation of proinflammatory cytokine responses in host macrophages

  Powell, P. P., Dixon, L. K. & Parkhouse, R. M. E., Dec 1996, In: Journal of Virology. 70, 12, p. 8527-8533 7 p.

  Research output: Contribution to journal › Article › peer-review
  148 Citations (Scopus)