Projects per year
Key Research Interests and Expertise
My primary research interest relates to the role of dietary flavonoids (naturally occurring compounds found in foods of plant origin) on health and wellbeing throughout the life course. To this extent, I have a particular interest and track-record in conducting human intervention studies (from acute, single dose studies, to longer-term studies lasting months /years), especially in populations at elevated risk of heart disease and diabetes. My research to date has predominantly focused on the impact of anthocyanins (e.g. berries, and some other fruits and vegetables), isoflavones (e.g. soy), flavanones (e.g. citrus fruits) and flavan-3-ols (e.g. cocoa, tea) and, with colleagues at the Department of Nutrition of Nutrition and Preventive Medicine, our principle focus is cardio-metabolic health and flavonoid bioavailability.
Details of our ongoing 6-month dose response blueberry study can be found here: http://www.blueberrystudy.org/. In this study, participants with confirmed metabolic syndrome are being assessed for insulin resistance (directly, and indirectly assessed) and a range of relevant endpoints; including endothelial function, arterial stiffness, cognition, lung function and the interaction with the microbiome (amongst other things).
In my role as trial coordinator in studies at UEA I have the fortuitous position of daily interaction with our dedicated study participants, and also benefit from working alongside a range of highly motivated scientists and PhD students, clinicians and research nurses.
Alongside my research role, I sit on the Norwich Medical School Research Committee and the Clinical Research Facility Joint Management Group.
Previous research experience has included assessing the impact of community based dietary interventions in a broad range of settings and I retain an interest in the role of exercise and activity in disease prevention and recuperation.
Research Group Membership
Department of Nutrition
- PhD Human Nutrition: Newcastle University (2006)
- M. Med. Sci. Human Nutrition: Sheffield University
- BA Human Movement Studies (sport and exercise science): 2:1 Leeds Metropolitan University
- Senior Research Fellow: Department of Nutrition and Preventive Medicine, Norwich Medical School, University of East Anglia: August 2006 to present.
- Research Associate: Human Nutrition Research Centre, Newcastle University: September 1997 to August 2006.
- Researcher: The Institute of Food Research, Colney: October 1996 to September 1997.
Expertise related to UN Sustainable Devlopment Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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1/04/13 → 31/07/22
31/05/21 → 8/08/21
- 18 Article
Blueberry anthocyanin intake attenuates the postprandial cardiometabolic effect of an energy-dense food challenge: results from a double blind, randomized controlled trial in metabolic syndrome participantsCurtis, P., Berends, L., van der Velpen, V., Jennings, A., Haag, L., Chandra, P., Kay, C., Rimm, E. B. & Cassidy, A., 27 Nov 2021, (E-pub ahead of print) In: Clinical Nutrition.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile
Blueberries improve biomarkers of cardiometabolic function in participants with metabolic syndrome—results from a 6-month, double-blind, randomized controlled trialCurtis, P. J., van der Velpen, V., Berends, L., Jennings, A., Feelisch, M., Umpleby, A. M., Evans, M., Fernandez, B. O., Meiss, M. S., Minnion, M., Potter, J., Minihane, A-M., Kay, C. D., Rimm, E. B. & Cassidy, A., 1 Jun 2019, In: The American Journal of Clinical Nutrition. 109, 6, p. 1535-1545 11 p.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile64 Citations (Scopus)15 Downloads (Pure)
Curtis, P., Burton-Freeman, B., Cassidy, A. & Kay, C. D., 20 Nov 2019, In: Molecules. 24, 23, 4220.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile12 Citations (Scopus)10 Downloads (Pure)
Association of oily fish intake, sex, age, BMI and APOE genotype with plasma long-chain n-3 fatty acid compositionFisk, H. L., Irvine, M., Miles, E. A., Lietz, G., Mathers, J. C., Packard, C. J., Armah, C. K., Kofler, B. M., Curtis, P. J., Minihane, A. M. & Calder, P. C., 14 Jul 2018, In: British Journal of Nutrition. 120, 1, p. 23-32
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile4 Citations (Scopus)26 Downloads (Pure)
Comparative bio-accessibility, bioavailability and bioequivalence of quercetin, apigenin, glucoraphanin and carotenoids from freeze-dried vegetables incorporated into a baked snack versus minimally processed vegetables: Evidence from in vitro models and a human bioavailability studyPerez-Moral, N., Saha, S., Philo, M., Hart, D. J., Winterbone, M. S., Hollands, W. J., Spurr, M., Bows, J., van der Velpen, V., Kroon, P. A. & Curtis, P. J., Sep 2018, In: Journal of Functional Foods. 48, p. 410-419 10 p.
Research output: Contribution to journal › Article › peer-reviewOpen AccessFile10 Citations (Scopus)35 Downloads (Pure)