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Personal profile

Biography

After gaining a 1st class (hon) MChem degree from the University of Leeds, U.K. (2006-2010), Rianne continued her studies at Leeds and gained a PhD in “Synthesis of novel functionalised β-ketoiminate and β-diketonate metal complexes for their use in anti-cancer treatment” (2010-2014) under the supervision of Professor Patrick McGowan. She then spent just over a year as a postdoctoral research associate at the University of Edinburgh, U.K., working with Professor Polly Arnold on the synthesis of low-valent uranium complexes supported by macrocyclic “Pacman” type ligands, and studied their abilities to activate small molecules. In August 2016, Rianne was awarded he first independent lectureship at the University of Bradford, where she delivered lectures and research projects in bioinorganic chemistry.

In both 2018 and 2019, Rianne was awarded an August-Wilhelm Scheer visitng professorship at the Technical University of Munch (TUM), where she worked with Professor Fritz Kühn on the synthesis of vanadium N-heteocyclic complexes for applications in catalysis and as potential anticancer compounds. Since August 2019, Rianne has been employed as Lecturer of Inorganic Chemistry at UEA, and more recently she was awarded a prestigious UKRI Future Leaders Fellowship on “Chemical and biological investigations of new vanadium compounds: determining their potential in the treatment of cancer”, which will be conducted between 2021-2025. 

See the groups website for further details.

 

Selected Publications

Rhodium(III) Dihalido Complexes: The Effect of Ligand Substitution and Halido Coordination on Increasing Cancer Cell PotencyR. M. Lord,* M. Zegke, A. M. Basri, C. M. Pask, P. C. McGowan, Inorg. Chem. 2021, 60, 3, 2076–2086

Bis(bipyridine)ruthenium(II) Ferrocenyl β‐Diketonate Complexes: Exhibiting Nanomolar Potency against Human Cancer Cell Lines, M. Allison, P. Caramés‐Méndez, C. M. Pask, R. M. Phillips, R. M. Lord,* P. C. McGowan* Chem. Eur. J. 2020 doi: 10.1002/chem.202004024 - accepted

β‐Diketonate versus β‐Ketoiminate: The Importance of a Ferrocenyl Moiety in Improving the Anticancer Potency M. Allison, D. Wilson, C. M. Pask, P. C. McGowan, R. M. Lord,* ChemBioChem 2020, 21(14), 1988-1996, doi: 10.1002/cbic.202000028

Influence of Ligand and Nuclearity on the Cytotoxicity of Cyclometallated C^N^C Platinum(II) Complexes A. Kergreis, R. M. Lord,* S. J. Pike* Chem. Eur. J. 2020, 25(65), 14938-14946 doi: 10.1002/chem.202002517

 

External Activities

  • Deputy Director of Admissions 
  • RSC departmental representative
  • RSC East Anglian Committee member

Teaching Interests

  • CHE-4301Y: Bonding, Structure and Periodicity
  • CHE-4602Y: Research Skills for Biochemistry
  • CHE-5301B: Inorganic Chemistry
  • CHE-6001Y: Research Projects
  • CHE-6003Y: Advanced Laboratory
  • CHE-6301Y: Inorganic Compounds - Structure and Function
  • CHE-6601Y: Protein Structure, Chemistry and Engineering
  • CHE-7001Y: Research Projects

Education/Academic qualification

Doctor of Philosophy, Univ Leeds, University of Leeds, Sch Chem

Oct 2010Apr 2014

Award Date: 24 Apr 2014

Master of Chemistry, Univ Leeds, University of Leeds, Sch Chem

Sep 2006Jul 2010

Award Date: 16 Jul 2010

External positions

Lecturer in Bioinorganic Chemistry, Univ Bradford, University of Bradford, Sch Chem & Biosci

Aug 2016Sep 2019

Research Associate, Univ Leeds, University of Leeds, Sch Chem

Sep 2015Apr 2016

Postdoctoral Research Associate, University of Edinburgh

Apr 2014May 2015

Network

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