Projects per year
Personal profile
Biography
After gaining a 1st class (hon) MChem degree from the University of Leeds, U.K. (2006-2010), Rianne continued her studies at Leeds and gained a PhD in “Synthesis of novel functionalised β-ketoiminate and β-diketonate metal complexes for their use in anti-cancer treatment” (2010-2014) under the supervision of Professor Patrick McGowan.
Rianne then spent just over a year as a postdoctoral research associate at the University of Edinburgh, U.K., working with Professor Polly Arnold on the synthesis of low-valent uranium complexes supported by macrocyclic “Pacman” type ligands, and studied their abilities to activate small molecules.
In August 2016, Rianne was awarded he first independent lectureship at the University of Bradford, where she delivered lectures and research projects in bioinorganic chemistry. During this time (2018 and 2019), Rianne was awarded an August-Wilhelm Scheer visitng professorship at the Technical University of Munch (TUM), where she worked with Professor Fritz Kühn on the synthesis of vanadium N-heteocyclic complexes for applications in catalysis and as potential anticancer compounds.
In August 2019, Rianne was employed as Lecturer of Inorganic Chemistry at UEA, and as of February 2021 she was awarded a prestigious UKRI Future Leaders Fellowship on “Chemical and biological investigations of new vanadium compounds: determining their potential in the treatment of cancer”, which will be conducted between 2021-2025.
See the groups website for further details.
Selected Publications
Bis(N-picolinamido)cobalt(II) Complexes Display Antifungal Activity toward Candida albicans and Aspergillus fumigatus L. H. D. Ghandhi, S. Bidula, C. M. Pask, R. M. Lord* and P. C. McGowan* ChemMedChem 2021, doi: 10.1002/cmdc.202100159 (just accepted) (Special issue: Metals in Medicine)
Understanding the Potential In Vitro Modes of Action of Bis(β-diketonato) Oxovanadium(IV) Complexes B. Sergi, I. Bulut, Y. Xia, Z. A. E. Waller, Y. Yildizhan, C. Acilan* and R. M. Lord* ChemMedChem 2021, 16(15), 2402-2410 (Special issue: Metals in Medicine)
Rhodium(III) Dihalido Complexes: The Effect of Ligand Substitution and Halido Coordination on Increasing Cancer Cell Potency, R. M. Lord,* M. Zegke, A. M. Basri, C. M. Pask, P. C. McGowan, Inorg. Chem. 2021, 60(3), 2076–2086
Bis(bipyridine)ruthenium(II) Ferrocenyl β‐Diketonate Complexes: Exhibiting Nanomolar Potency against Human Cancer Cell Lines, M. Allison, P. Caramés‐Méndez, C. M. Pask, R. M. Phillips, R. M. Lord,* P. C. McGowan* Chem. Eur. J. 2021, 27(11), 3737-3744
Teaching Interests
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CHE-4301Y: Bonding, Structure and Periodicity - tutorials
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CHE-5301B: Inorganic Chemistry - tutorials
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CHE-6001Y: Research Projects
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CHE-6003Y: Advanced Laboratory
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CHE-7001Y: Research Projects
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CHE-7301Y: Advanced Topics in Inorganic Chemistry
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BIO-7017A: Frontiers in Molecular Medicine
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, University of Leeds
Oct 2010 → Apr 2014
Award Date: 24 Apr 2014
Master of Chemistry, University of Leeds
Sep 2006 → Jul 2010
Award Date: 16 Jul 2010
External positions
Lecturer in Bioinorganic Chemistry, University of Bradford
Aug 2016 → Sep 2019
Research Associate, University of Leeds
Sep 2015 → Apr 2016
Postdoctoral Research Associate, University of Edinburgh
Apr 2014 → May 2015
Network
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Synthesis and characterisation of vanadium complexes and their potential in the treatment of cancer.
1/10/21 → 30/09/23
Project: Training
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Addressing Interdisciplinary challenges through Raman Microscopy - a new facility for UEA
Lettice, F., Alexander, M., Askounis, A., Baker, A., Cammidge, A., Chao, Y., Fabian, L., Fielden, J., Hernaez, M., Hui, O., Kaplani, E., Khimyak, Y., Liss, P., Lord, R., Marin, M. J., Mayes, A., Melendi-Espina, S., Nolte, S., Romanov, A., Saeed, A., Sobolewski, A., Tolhurst, T. & Wright, J.
Engineering and Physical Sciences Research Council
6/11/20 → 31/08/22
Project: Research
Research output
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Water-soluble copper pyrithione complexes with cytotoxic and antibacterial activity
Mishra, A., Djoko, K. Y., Lee, Y-H., Lord, R. M., Kaul, G., Akhir, A., Saxena, D., Chopra, S. & Walton, J. W., 28 Mar 2023, In: Organic & Biomolecular Chemistry. 21, 12, p. 2539-2544 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Bis(phenyl-β-diketonato)titanium(IV) ethoxide complexes: Ring-opening polymerization of L-lactide by solvent-free microwave irradiation
Lord, R. M., Janeway, F. D., Bird, L. & McGowan, P. C., 1 Jan 2022, In: Polyhedron. 211, 115520.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)7 Downloads (Pure) -
Heterometallic Ferrocenyl Complexes and Their Application in the Treatment of Cancer
Lord, R. M., Hofmann, B. J. & Stringer, T., 16 Dec 2022, Encyclopedia of Inorganic and Bioinorganic Chemistry. Scott, R. A. (ed.). Wiley, 27 p.Research output: Chapter in Book/Report/Conference proceeding › Entry for encyclopedia/dictionary
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Medicinal applications of early transition metal β-diketonato complexes
Stringer, T. & Lord, R. M., 14 Dec 2022, Organometallic Chemistry. Patmore, N. J. & Elliott, P. I. P. (eds.). Royal Society of Chemistry, Vol. 44. p. 92-109 18 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review
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Bis(bipyridine)ruthenium(II) ferrocenyl β‐diketonate complexes: exhibiting nanomolar potency against human cancer cell lines
Allison, M., Caramés-Méndez, P., Pask, C. M., Phillips, R. M., Lord, R. M. & McGowan, P. C., 19 Feb 2021, In: Chemistry - A European Journal. 27, 11, p. 3737-3744 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)4 Downloads (Pure)
Activities
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Dalton 2023
Rianne Lord (Speaker)
18 Apr 2023 → 20 Apr 2023Activity: Participating in or organising an event › Participation in conference
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Organometallics (Journal)
Rianne Lord (Editorial board member)
Jan 2023 → …Activity: Editorial work › Publication editorial role
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Top of the Bench - Event Organiser
Rianne Lord (Organiser)
31 Oct 2022 → 25 Nov 2022Activity: Participating in or organising an event › Schools engagement
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Metal-Based Complexes for Biomedical Applications Symposium
Rianne Lord (Speaker)
24 Oct 2022Activity: Participating in or organising an event › Public lecture/debate/seminar
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Technical University of Munich
Rianne Lord (Visiting researcher)
Oct 2022 → Dec 2022Activity: Visiting an external institution › Visiting an external academic institution