• 1.24 Chemistry

Accepting PhD Students

PhD projects

We have a fully funded PhD position open (details below) and we are also open to taking students who have secured their own research funding. Please contact Dr Rianne Lord for more details and to discuss suitable support.

Personal profile

Postgraduate Research Opportunities

We currently have a 4-year funded PhD studentship available in collaboration with Prof. Mark Webber at the Quadram Institute (Norwich Research Park). The project will focus on the design and synthesis of new metallodrugs and assessing their activities and modes of action in the treatment of antimicrobial resistance. Please apply using the link below, and contact Dr Lord with any informal inquiries.

Deadline for the application: 20th November 2023

https://biodtp.norwichresearchpark.ac.uk/projects/new-tools-for-old-foes-developing-a-new-class-of-antimicrobial-metallodrugs/

 

Biography

After gaining a 1st class (hon) MChem degree from the University of Leeds, U.K. (2006-2010), Rianne continued her studies at Leeds and gained a PhD titled “Synthesis of novel functionalised β-ketoiminate and β-diketonate metal complexes for their use in anti-cancer treatment” (2010-2014) under the supervision of Professor Patrick McGowan. She then spent just over a year as a postdoctoral research associate at the University of Edinburgh, U.K., working with Professor Polly Arnold on the synthesis of low-valent uranium complexes supported by macrocyclic “Pacman” type ligands, and studied their abilities to activate small molecules.

In August 2016, Rianne was awarded he first independent lectureship at the University of Bradford. During this time (2018 and 2019), she was awarded two August-Wilhelm Scheer visitng professorships at the Technical University of Munch (TUM), where she worked with Professor Fritz Kühn on the synthesis of vanadium N-heteocyclic complexes for applications in catalysis and as potential anticancer compounds.

In August 2019, Rianne was employed as Lecturer of Inorganic Chemistry at UEA, and as of February 2021 she was awarded a UKRI Future Leaders Fellowship on “Chemical and biological investigations of new vanadium compounds: determining their potential in the treatment of cancer”, which will be conducted between 2021-2025. As of August 2022, Rianne was promoted to Associate Professor and awarded a TUM Global visiting professorship to work with Prof. Angela Casini on new metallodrugs.

See the groups website for further details.

Selected Publications

Cytotoxicity of Ruthenium(II) Arene Complexes Containing Functionalized Ferrocenyl β-Diketonate Ligands, M. Allison, P. Caramés-Méndez, B. J. Hofmann, C. M. Pask, R. M. Phillips, R. M. Lord* and P. C. McGowan* Organometallics, 2023, accepted manuscript.

Water-soluble copper pyrithione complexes with cytotoxic and antibacterial activity, A. Mishra, K. Djoko, Y.-H. Lee, R. M. Lord, G. Kaul, A. Akhir, D. Saxena, S. Chopra and J. W. Walton, Organic & Biomolecular Chemistry, 2023, 21, 2539-2544

Bis(N-picolinamido)cobalt(II) Complexes Display Antifungal Activity toward Candida albicans and Aspergillus fumigatus L. H. D. Ghandhi, S. Bidula, C. M. Pask, R. M. Lord* and P. C. McGowan* ChemMedChem 2021,16(20), 3210-3221 (Special issue: Metals in Medicine)

Understanding the Potential In Vitro Modes of Action of Bis(β-diketonato) Oxovanadium(IV) Complexes B. Sergi, I. Bulut, Y. Xia, Z. A. E. Waller, Y. Yildizhan, C. Acilan* and R. M. Lord* ChemMedChem 2021, 16(15), 2402-2410 (Special issue: Metals in Medicine)

Rhodium(III) Dihalido Complexes: The Effect of Ligand Substitution and Halido Coordination on Increasing Cancer Cell PotencyR. M. Lord,* M. Zegke, A. M. Basri, C. M. Pask, P. C. McGowan, Inorg. Chem. 2021, 60(3), 2076–2086

Bis(bipyridine)ruthenium(II) Ferrocenyl β‐Diketonate Complexes: Exhibiting Nanomolar Potency against Human Cancer Cell Lines, M. Allison, P. Caramés‐Méndez, C. M. Pask, R. M. Phillips, R. M. Lord,* P. C. McGowan* Chem. Eur. J. 2021, 27(11), 3737-3744

Teaching Interests

  • CHE-4301Y: Bonding, Structure and Periodicity - tutorials

  • CHE-5301B: Inorganic Chemistry - tutorials

  • CHE-6001Y: BSc Research Projects

  • CHE-6005B: Advanced Laboratory Skills

  • CHE-7001Y: MSc Research Projects

  • CHE-7301Y: Advanced Topics in Inorganic Chemistry

  • BIO-7017A: Frontiers in Molecular Medicine

  • BIO-7042X: MSc Research Projects

Key Responsibilities

  • Deputy director of admissions 
  • RSC East Anglia committee member
  • School of Chemistry RSC representative 
  • UK representative on the COST action CA18202 - Network for Equilibria and Chemical Thermodynamics Advanced Research 
  • Early career advisory board member for the European Journal of Inorganic Chemistry
  • Editorial board member for ACS Organometallics 

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

Doctor of Philosophy, University of Leeds

Oct 2010Apr 2014

Award Date: 24 Apr 2014

Master of Chemistry, University of Leeds

Sep 2006Jul 2010

Award Date: 16 Jul 2010

External positions

Lecturer in Bioinorganic Chemistry, University of Bradford

Aug 2016Sep 2019

Research Associate, University of Leeds

Sep 2015Apr 2016

Postdoctoral Research Associate, University of Edinburgh

Apr 2014May 2015

Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or