Robert Field

Search results

• 2007

  Chemical and chemoenzymatic synthesis of glycosyl-amino acids and glycopeptides related to Trypanosoma cruzi mucins

  Campo, V. L., Carvalho, I., Allman, S., Davis, B. G. & Field, R. A., 2007, In: Organic and Biomolecular Chemistry. 5, 16, p. 2645-2657 13 p.

  Research output: Contribution to journal › Article › peer-review
  42 Citations (Scopus)

• Chemoenzymatic synthesis with distinct Pasteurella heparosan synthases: Monodisperse polymers and unnatural structures

  Sismey-Ragatz, A. E., Green, D. E., Otto, N. J., Rejzek, M., Field, R. A. & DeAngelis, P. L., 28 Sept 2007, In: Journal of Biological Chemistry. 282, 39, p. 28321-28327 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  81 Citations (Scopus)

• Direct oxidation of sugar nucleotides to the corresponding uronic acids: TEMPO and platinum-based procedures

  Rejzek, M., Mukhopadhyay, B., Wenzel, C. Q., Lam, J. S. & Field, R. A., 26 Feb 2007, In: Carbohydrate Research. 342, 3-4, p. 460-466 7 p.

  Research output: Contribution to journal › Article › peer-review
  18 Citations (Scopus)

• Emerging glycomics technologies

  Turnbull, J. E. & Field, R. A., Feb 2007, In: Nature Chemical Biology. 3, 2, p. 74-77 4 p.

  Research output: Contribution to journal › Article › peer-review
  145 Citations (Scopus)

• Glyconanoparticles for the colorimetric detection of cholera toxin

  Schofield, C. L., Field, R. A. & Russell, D. A., 2007, In: Analytical Chemistry. 79, 4, p. 1356-1361 6 p.

  Research output: Contribution to journal › Article › peer-review
  208 Citations (Scopus)

• Identification and biochemical characterization of two novel UDP-2,3-diacetamido-2,3-dideoxy-α-D-glucuronic acid 2-epimerases from respiratory pathogens

  Westman, E. L., Mcnally, D. J., Rejzek, M., Miller, W. L., Kannathasan, V. S., Preston, A., Maskell, D. J., Field, R. A., Brisson, J. R. & Lam, J. S., 1 Jul 2007, In: Biochemical Journal. 405, 1, p. 123-130 8 p.

  Research output: Contribution to journal › Article › peer-review
  18 Citations (Scopus)

• New thiopyrazolo[3,4-d]pyrimidine derivatives as anti-mycobacterial agents

  Ballell, L., Field, R. A., Chung, G. A. C. & Young, R. J., 15 Mar 2007, In: Bioorganic and Medicinal Chemistry Letters. 17, 6, p. 1736-1740 5 p.

  Research output: Contribution to journal › Article › peer-review
  112 Citations (Scopus)

• Predicting Protein Function from Structure-The Roles of Short-chain Dehydrogenase/Reductase Enzymes in Bordetella O-antigen Biosynthesis

  King, J. D., Harmer, N. J., Preston, A., Palmer, C. M., Rejzek, M., Field, R. A., Blundell, T. L. & Maskell, D. J., 30 Nov 2007, In: Journal of Molecular Biology. 374, 3, p. 749-763 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  20 Citations (Scopus)

• Recent applications of the Cu^I-catalysed Huisgen azide-alkyne 1,3-dipolar cycloaddition reaction in carbohydrate chemistry

  Dedola, S., Nepogodiev, S. A. & Field, R. A., 2007, In: Organic and Biomolecular Chemistry. 5, 7, p. 1006-1017 12 p.

  Research output: Contribution to journal › Article › peer-review
  252 Citations (Scopus)

• RmlC, a C3' and C5' carbohydrate epimerase, appears to operate via an intermediate with an unusual twist boat conformation

  Dong, C., Major, L. L., Srikannathasan, V., Errey, J. C., Giraud, M-F., Lam, J. S., Graninger, M., Messner, P., McNeil, M. R., Field, R. A., Whitfield, C. & Naismith, J. H., 5 Jan 2007, In: Journal of Molecular Biology. 365, 1, p. 146-59 14 p.

  Research output: Contribution to journal › Article › peer-review
  54 Citations (Scopus)

• Synthesis of triazole-linked pseudo-starch fragments

  Nepogodiev, S. A., Dedola, S., Marmuse, L., de Oliveira, M. T. & Field, R. A., 26 Feb 2007, In: Carbohydrate Research. 342, 3-4, p. 529-540 12 p.

  Research output: Contribution to journal › Article › peer-review
  46 Citations (Scopus)
• 2006

  Characterisation of Streptomyces spheroides NovW and revision of its functional assignment to a dTDP-6-deoxy-D-xylo-4-hexulose 3-epimerase

  Tello, M., Jakimowicz, P., Errey, J. C., Freel Meyers, C. L., Walsh, C. T., Buttner, M. J., Lawson, D. M. & Field, R. A., 2006, In: Chemical Communications. 10, p. 1079-1081 3 p.

  Research output: Contribution to journal › Article › peer-review
  21 Citations (Scopus)

• Contrasting reactivity of thioglucoside and selenoglucoside donors towards promoters: Implications for glycosylation stereocontrol

  van Well, R. M., Kärkkäinen, T. S., Kartha, K. P. R. & Field, R. A., 24 Jul 2006, In: Carbohydrate Research. 341, 10, p. 1391-1397 7 p.

  Research output: Contribution to journal › Article › peer-review
  34 Citations (Scopus)

• Convergent synthesis of a trisaccharide as its 2-(trimethylsilyl)ethyl glycoside related to the flavonoid triglycoside from Gymnema sylvestre

  Mukhopadhyay, B. & Field, R. A., 24 Jul 2006, In: Carbohydrate Research. 341, 10, p. 1697-1701 5 p.

  Research output: Contribution to journal › Article › peer-review
  15 Citations (Scopus)

• Direct synthesis of chiral aziridines from N-tert-butyl-sulfinylketimines

  Morton, D., Pearson, D., Field, R. A. & Stockman, R. A., 2006, In: Chemical Communications. 17, p. 1833-1835 3 p.

  Research output: Contribution to journal › Article › peer-review
  60 Citations (Scopus)

• Expression and initial characterization of WbbI, a putative d-Galf:α-d-Glc β-1,6-galactofuranosyltransferase from Escherichia coli K-12

  Wing, C., Errey, J. C., Mukhopadhyay, B., Blanchard, J. S. & Field, R. A., 2006, In: Organic and Biomolecular Chemistry. 4, 21, p. 3945-3950 6 p.

  Research output: Contribution to journal › Article › peer-review
  37 Citations (Scopus)

• Silver and gold glyconanoparticles for colorimetric bioassays

  Schofield, C. L., Haines, A. H., Field, R. A. & Russell, D. A., 1 Jul 2006, In: Langmuir. 22, 15, p. 6707-6711 5 p.

  Research output: Contribution to journal › Article › peer-review
  216 Citations (Scopus)

• The 1.6-Å resolution crystal structure of NovW: A 4-keto-6-deoxy sugar epimerase from the novobiocin biosynthetic gene cluster of Streptomyces spheroides

  Jakimowicz, P., Tello, M., Freel Meyers, C. L., Walsh, C. T., Buttner, M. J., Field, R. A. & Lawson, D. M., 1 Apr 2006, In: Proteins: Structure, Function and Genetics. 63, 1, p. 261-265 5 p.

  Research output: Contribution to journal › Article › peer-review
  17 Citations (Scopus)
• 2005

  "Click chemistry" en route to pseudo-starch

  Marmuse, L., Nepogodiev, S. A. & Field, R. A., 21 Jun 2005, In: Organic and Biomolecular Chemistry. 3, 12, p. 2225-2227 3 p.

  Research output: Contribution to journal › Article › peer-review
  50 Citations (Scopus)

• Efficient synthesis of methyl lycotetraoside, the tetrasaccharide constituent of the tomato defence glycoalkaloid α-tomatine

  Jones, N. A., Nepogodiev, S. A. & Field, R. A., 7 Sept 2005, In: Organic and Biomolecular Chemistry. 3, 17, p. 3201-3206 6 p.

  Research output: Contribution to journal › Article › peer-review
  8 Citations (Scopus)

• Exploiting an aromatic aglycone as a reporter of glycosylation stereochemistry in the synthesis of 1,6-linked maltooligosaccharides

  Marmuse, L., Nepogodiev, S. A. & Field, R. A., 24 Jan 2005, In: Tetrahedron Asymmetry. 16, 2, p. 477-485 9 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• From solution phase to “on-column” chemistry: Trichloroacetimidate-based glycosylation promoted by perchloric acid−silica

  Mukhopadhyay, B., Maurer, S. V., Rudolph, N., van Well, R. M., Russell, D. A. & Field, R. A., 2005, In: Journal of Organic Chemistry. 70, 22, p. 9059-9062 4 p.

  Research output: Contribution to journal › Article › peer-review
  64 Citations (Scopus)

• Glycosylation reactions with 'disarmed' thioglycoside donors promoted by N-iodosuccinimide and HClO₄-silica

  Mukhopadhyay, B., Collet, B. & Field, R. A., 29 Aug 2005, In: Tetrahedron Letters. 46, 35, p. 5923-5925 3 p.

  Research output: Contribution to journal › Article › peer-review
  57 Citations (Scopus)

• Glycosylation with in situ separation: Carbohydrate chemistry on a TLC plate

  Mukhopadhyay, B., Cura, P., Kartha, K. P. R., Botting, C. H. & Field, R. A., 7 Oct 2005, In: Organic and Biomolecular Chemistry. 3, 19, p. 3468-3470 3 p.

  Research output: Contribution to journal › Article › peer-review
  10 Citations (Scopus)

• Iodine promoted glycosylation with glycosyl iodides: α-glycoside synthesis

  van Well, R. M., Kartha, K. P. R. & Field, R. A., 2005, In: Journal of Carbohydrate Chemistry. 24, 4-6, p. 463-474 12 p.

  Research output: Contribution to journal › Article › peer-review
  49 Citations (Scopus)

• One-pot acetalation–acetylation of sugar derivatives employing perchloric acid immobilised on silica

  Mukhopadhyay, B., Russell, D. A. & Field, R. A., 2005, In: Carbohydrate Research. 340, 6, p. 1075-1080 6 p.

  Research output: Contribution to journal › Article › peer-review
  53 Citations (Scopus)

• Probing the breadth of macrolide glycosyltransferases: in vitro remodeling of a polyketide antibiotic creates active bacterial uptake and enhances potency

  Yang, M., Proctor, M. R., Bolam, D. N., Errey, J. C., Field, R. A., Gilbert, H. J. & Davis, B. G., 6 Jul 2005, In: Journal of the American Chemical Society. 127, 26, p. 9336-9337 2 p.

  Research output: Contribution to journal › Article › peer-review
  79 Citations (Scopus)

• Synthesis and evaluation of mimetics of UDP and UDP-α-D-galactose, dTDP and dTDP-α-D-glucose with monosaccharides replacing the key pyrophosphate unit

  Ballell, L., Young, R. J. & Field, R. A., 21 Mar 2005, In: Organic and Biomolecular Chemistry. 3, 6, p. 1109-1115 7 p.

  Research output: Contribution to journal › Article › peer-review
  24 Citations (Scopus)

• Synthesis of a 2,3,4-triglycosylated rhamnoside fragment of rhamnogalacturonan-II side chain a using a late stage oxidation approach

  Chauvin, A. L., Nepogodiev, S. A. & Field, R. A., 4 Feb 2005, In: Journal of Organic Chemistry. 70, 3, p. 960-966 7 p.

  Research output: Contribution to journal › Article › peer-review
  38 Citations (Scopus)

• Synthesis of the branched-chain sugar aceric acid: A unique component of the pectic polysaccharide rhamnogalacturonan-II

  Jones, N. A., Nepogodiev, S. A., Macdonald, C. J., Hughes, D. L. & Field, R. A., 1 Oct 2005, In: The Journal of Organic Chemistry. 70, 21, p. 8556-8559 4 p.

  Research output: Contribution to journal › Article › peer-review
  20 Citations (Scopus)

• Thioctic acid amides: convenient tethers for achieving low nonspecific protein binding to carbohydrates presented on gold surfaces

  Karamanska, R., Mukhopadhyay, B., Russell, D. A. & Field, R. A., 2005, In: Chemical Communications. 26, p. 3334-3336 3 p.

  Research output: Contribution to journal › Article › peer-review
  48 Citations (Scopus)

• Xenopus as a model organism in developmental chemical genetic screens

  Tomlinson, M. L., Field, R. A. & Wheeler, G. N., 2005, In: Molecular BioSystems. 1, 3, p. 223-228 6 p.

  Research output: Contribution to journal › Article › peer-review
  45 Citations (Scopus)
• 2004

  A convenient synthesis of chiral nonracemic vinyl aziridines

  Morton, D., Pearson, D., Field, R. A. & Stockman, R. A., 8 Jul 2004, In: Organic Letters. 6, 14, p. 2377-2380 4 p.

  Research output: Contribution to journal › Article › peer-review
  98 Citations (Scopus)

• Enzymatic liberation of lycotetraose from the Solanum glycoalkaloid alpha-tomatine

  Woods, K., Hamilton, C. J. & Field, R. A., 2004, In: Carbohydrate Research. 339, 13, p. 2325-2328 4 p.

  Research output: Contribution to journal › Article
  14 Citations (Scopus)

• Flexible enzymatic and chemo-enzymatic approaches to a broad range of uridine-diphospho-sugars

  Errey, J. C., Mukhopadhyay, B., Kartha, K. P. R. & Field, R. A., 7 Dec 2004, In: Chemical Communications. 23, p. 2706-2707 2 p.

  Research output: Contribution to journal › Article › peer-review
  65 Citations (Scopus)

• Practical de-O-acylation reactions promoted by molecular sieves

  Kartha, K. P. R., Mukhopadhyay, B. & Field, R. A., 25 Feb 2004, In: Carbohydrate Research. 339, 3, p. 729-732 4 p.

  Research output: Contribution to journal › Article › peer-review
  27 Citations (Scopus)

• Rationalising the effect of reducing agent on the oxazaborolidine-mediated asymmetric reduction of N-substituted imines

  Kirton, E. H. M., Tughan, G., Morris, R. E. & Field, R. A., 19 Jan 2004, In: Tetrahedron Letters. 45, 4, p. 853-855 3 p.

  Research output: Contribution to journal › Article › peer-review
  18 Citations (Scopus)

• Streamlined synthesis of per-O-acetylated sugars, glycosyl iodides, or thioglycosides from unprotected reducing sugars

  Mukhopadhyay, B., Kartha, K. P. R., Russell, D. A. & Field, R. A., 1 Oct 2004, In: Journal of Organic Chemistry. 69, 22, p. 7758-7760 3 p.

  Research output: Contribution to journal › Article › peer-review
  137 Citations (Scopus)

• Synthesis of an apiose-containing disaccharide fragment of rhamnogalacturonan-II and some analogues

  Chauvin, A-L., Nepogodiev, S. A. & Field, R. A., 2 Jan 2004, In: Carbohydrate Research. 339, 1, p. 21-27 7 p.

  Research output: Contribution to journal › Article › peer-review
  20 Citations (Scopus)

• Synthesis of L-arabinose-containing fragments of the oat root saponin Avenacin A-1

  Mukhopadhyay, B. & Field, R. A., 17 May 2004, In: Carbohydrate Research. 339, 7, p. 1285-1291 7 p.

  Research output: Contribution to journal › Article › peer-review
  12 Citations (Scopus)

• The position of a key tyrosine in dTDP-4-keto-6-deoxy-D-glucose-5-epimerase (EvaD) alters the substrate profile for this RmlC-like enzyme

  Merkel, A. B., Major, L. L., Errey, J. C., Burkart, M. D., Field, R. A., Walsh, C. T. & Naismith, J. H., 30 Jul 2004, In: Journal of Biological Chemistry. 279, 31, p. 32684-32691 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  24 Citations (Scopus)
• 2003

  A simple one-pot method for the synthesis of partially protected mono- and disaccharide building blocks using an orthoesterification-benzylation-orthoester rearrangement approach

  Mukhopadhyay, B. & Field, R. A., 26 Sept 2003, In: Carbohydrate Research. 338, 20, p. 2149-2152 4 p.

  Research output: Contribution to journal › Article › peer-review
  46 Citations (Scopus)

• Corey-Chaykovsky reaction of chiral sulfinyl imines: A convenient procedure for the formation of chiral aziridines

  Morton, D., Pearson, D., Field, R. A. & Stockman, R. A., 2003, In: Synlett. 13, p. 1985-1988 4 p.

  Research output: Contribution to journal › Article › peer-review
  53 Citations (Scopus)

• Observations on iodine-promoted β-mannosylation

  Marsh, S. J., Kartha, K. P. R. & Field, R. A., 2003, In: Synlett. 9 SPEC. ISS., p. 1376-1378 3 p.

  Research output: Contribution to journal › Article › peer-review
  22 Citations (Scopus)

• Practical synthesis of the 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucosides of Fmoc-serine and Fmoc-threonine and their benzyl esters

  Carvalho, I., Scheuerl, S. L., Kartha, K. P. R. & Field, R. A., 1 May 2003, In: Carbohydrate Research. 338, 10, p. 1039-1043 5 p.

  Research output: Contribution to journal › Article › peer-review
  29 Citations (Scopus)

• Preparation, X-ray structure and reactivity of a stable glycosyl iodide

  Bickley, J., Cottrell, J. A., Ferguson, J. R., Field, R. A., Harding, J. R., Hughes, D. L., Ravindanathan Kartha, K. P., Law, J. L., Scheinmann, F. & Stachulski, A. V., 1 Jan 2003, In: Chemical Communications. 11, p. 1266-1267 2 p.

  Research output: Contribution to journal › Article › peer-review
  30 Citations (Scopus)

• Structural and mechanistic basis of bacterial sugar nucleotide-modifying enzymes

  Field, R. A. & Naismith, J. H., 1 Jul 2003, In: Biochemistry. 42, 25, p. 7637-7647 11 p.

  Research output: Contribution to journal › Article › peer-review
  29 Citations (Scopus)
• 2002

  Observations on chemical and enzymatic approaches to α-2,3-sialylated octyl β-lactoside

  Turnbull, W. B., Harrison, J. A., Kartha, K. P. R., Schenkman, S. & Field, R. A., 15 Apr 2002, In: Tetrahedron. 58, 16, p. 3207-3216 10 p.

  Research output: Contribution to journal › Article › peer-review
  20 Citations (Scopus)
• 2001

  Hydrolase and sialyltransferase activities of Trypanosoma cruzi trans-sialidase towards NeuAc-α-2,3-Gal-β-O-PNP

  Harrison, J. A., Kartha, K. P. R., Turnbull, W. B., Scheuerl, S. L., Naismith, J. H., Schenkman, S. & Field, R. A., 22 Jan 2001, In: Bioorganic and Medicinal Chemistry Letters. 11, 2, p. 141-144 4 p.

  Research output: Contribution to journal › Article › peer-review
  25 Citations (Scopus)

• Iodine and its interhalogen compounds: Versatile reagents in carbohydrate chemistry. XIV. Glycosylated amino acid synthesis

  Kartha, K. P. R., Ballell, L., Bilke, J., McNeil, M. & Field, R. A., 2001, In: Journal of the Chemical Society. Perkin Transactions 1. 8, p. 770-772 3 p.

  Research output: Contribution to journal › Article › peer-review
  32 Citations (Scopus)