Projects per year
Personal profile
Areas of Expertise
Sexual Reproduction, Genomics, Reproductive Biology, Genetics, Sperm
Key Research Interests
An inescapable consequence of sex in eukaryotes is the evolution of two sexes, generally are these males and females and two phases of the life cycle, a haploid and diploid phase. The existence of two sexes and two ploidy levels has important evolutionary consequences, which lie at the heart of our research. We aim to understand how selection acting at the diploid level affects the evolution of haploid gametes and in turn how selection at the haploid level affects the evolution of the diploid organism. We are particularly interested in the evolution of anisogamy and how postcopulatory sexual selection shapes the evolution of gametes, the evolution of different ploidy levels, the importance of sperm-mediated genetic and epigenetic effects and the evolution of sexual dimorphism and sex determination. We use a multitude of study organisms including the zebrafish Danio rerio, the Atlantic salmon Salmo salar, the filamentous fungus Neurospora crassa and the fission yeast Schizosaccharomyces pombe and combine different approaches such as comparative methods, experimental evolution and selection experiments, mathematical modeling, genetics and genomics.
Research Group or Lab Membership
Ding He - postdoctoral researcher
Ghazal Alavioon - postdoctoral researcher
Claire Armstrong - postdoctoral researcher
Berrit Kiehl - PhD student
David Murray - research asssistant
Rozalia Korbut - research assistant
Academic Background
Our lab website can be found at: https://simoneimmler.com/
We are on Twitter: @SimoneImmler
Education/Academic qualification
Doctor of Philosophy, University of Sheffield
… → 2006
Master of Science, University of Basel
… → 2001
Media Expertise
- Biology
- Fertility
- Evolution
Collaborations and top research areas from the last five years
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The mechanisms and adaptive value of transgenerational epigenetic effects
Maklakov, A., Chapman, T., Immler, S. & Duxbury, E.
1/10/23 → 30/09/27
Project: Research
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Testing the Evolutionary Consequences of Haploid Selection in Animals
1/01/22 → 31/12/26
Project: Research
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Half Life: Interactions between haploid selection and life histories
1/11/20 → 16/02/25
Project: Fellowship
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Investment ready - preparing Virilitas Labs business launch
Anglia Innovation Partnership LLP
1/02/23 → 30/06/23
Project: Other
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Understanding the role of selection at the gametic level in adaptation to changing environments
Immler, S., Dalmay, T., Gage, M. & Moxon, S.
Natural Environment Research Council
31/08/19 → 30/11/22
Project: Research
Research output
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Frequency-dependent viscosity of salmon ovarian fluid has biophysical implications for sperm–egg interactions
Graziano, M., Palit, S., Yethiraj, A., Immler, S., Gage, M. J. G. & Purchase, C. F., 13 Jan 2023, In: Journal of Experimental Biology. 226, 1, jeb244712.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)4 Downloads (Pure) -
The potential role of the mobile and non-coding genomes in adaptive response
Godden, A. M. & Immler, S., Jan 2023, In: Trends in Genetics. 39, 1, p. 5-8 4 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Downloads (Pure) -
Accounting for the genetic load in assisted reproductive technology
van Oosterhout, C., Marcu, D. & Immler, S., May 2022, In: Clinical and Translational Medicine. 12, 5, e864.Research output: Contribution to journal › Comment/debate › peer-review
Open AccessFile11 Downloads (Pure) -
Evolutionary history of sexual selection affects microRNA profiles in Drosophila sperm
Hotzy, C., Fowler, E., Kiehl, B., Francis, R., Mason, J., Moxon, S., Rostant, W., Chapman, T. & Immler, S., Feb 2022, In: Evolution. 76, 2, p. 310-319 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)10 Downloads (Pure) -
Frequency-dependent viscosity of salmon ovarian fluid has biophysical implications for sperm-egg interactions
Graziano, M., Palit, S., Yethiraj, A., Immler, S., Gage, M. JG. & Purchase, C., 27 Jun 2022, biorxiv.Research output: Working paper › Preprint
Open Access
Press/Media
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Study finds ‘old’ sperm produces healthier offspring
17/02/19
1 item of Media coverage
Press/Media: Press / Media
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Women's bodies BLOCK weak sperm by creating a 'bottleneck' in the uterus where stronger swimmers force their way through
14/02/19
1 item of Media coverage
Press/Media: Press / Media
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'Old' sperm produces healthier offspring
14/02/19
1 item of Media coverage
Press/Media: UEA Press Release
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Offspring from older sperm are fitter and age more slowly
14/02/19
1 item of Media coverage
Press/Media: Press / Media
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Not every sperm is sacred: Longer-lived sperm produce healthier offspring
10/07/17
1 item of Media coverage
Press/Media: Press / Media