Projects per year
Personal profile
Areas of Expertise
Sexual Reproduction, Genomics, Reproductive Biology, Genetics, Sperm
Key Research Interests
An inescapable consequence of sex in eukaryotes is the evolution of two sexes, generally are these males and females and two phases of the life cycle, a haploid and diploid phase. The existence of two sexes and two ploidy levels has important evolutionary consequences, which lie at the heart of our research. We aim to understand how selection acting at the diploid level affects the evolution of haploid gametes and in turn how selection at the haploid level affects the evolution of the diploid organism. We are particularly interested in the evolution of anisogamy and how postcopulatory sexual selection shapes the evolution of gametes, the evolution of different ploidy levels, the importance of sperm-mediated genetic and epigenetic effects and the evolution of sexual dimorphism and sex determination. We use a multitude of study organisms including the zebrafish Danio rerio, the Atlantic salmon Salmo salar, the filamentous fungus Neurospora crassa and the fission yeast Schizosaccharomyces pombe and combine different approaches such as comparative methods, experimental evolution and selection experiments, mathematical modeling, genetics and genomics.
Research Group or Lab Membership
Ding He - postdoctoral researcher
Ghazal Alavioon - postdoctoral researcher
Claire Armstrong - postdoctoral researcher
Berrit Kiehl - PhD student
David Murray - research asssistant
Rozalia Korbut - research assistant
Academic Background
Our lab website can be found at: https://simoneimmler.com/
We are on Twitter: @SimoneImmler
Education/Academic qualification
Doctor of Philosophy, Ph.D., Evolutionary Biology, University of Sheffield
… → 2006
Master of Science, M.Sc., Evolutionary Biology, University of Basel
… → 2001
Media Expertise
- Biology
- Fertility
- Evolution
Collaborations and top research areas from the last five years
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The mechanisms and adaptive value of transgenerational epigenetic effects
Maklakov, A., Chapman, T., Immler, S. & Duxbury, E.
1/10/23 → 30/09/27
Project: Research
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Testing the Evolutionary Consequences of Haploid Selection in Animals
1/01/22 → 31/12/26
Project: Research
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Half Life: Interactions between haploid selection and life histories
1/11/20 → 16/02/25
Project: Fellowship
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Investment ready - preparing Virilitas Labs business launch
Anglia Innovation Partnership LLP
1/02/23 → 30/06/23
Project: Other
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Gametic selection favours polyandry and selfing
Scott, M. F., Mackintosh, C. & Immler, S., 16 Feb 2024, In: PLoS Genetics. 20, 2, e1010660.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Heatwave-induced paternal effects have limited adaptive benefits in offspring
Irish, S. D., Sutter, A., Pinzoni, L., Sydney, M. C., Travers, L., Murray, D., de Coriolis, J-C. & Immler, S., Oct 2024, In: Ecology and Evolution. 14, 10, e70399.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Downloads (Pure) -
One-factor sex determination evolves without linkage between feminizing and masculinizing mutations
Scott, M. F. & Immler, S., 10 Jul 2024, In: Proceedings of the Royal Society B: Biological Sciences. 291, 2026, 20240693.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure) -
Paternal starvation affects metabolic gene expression during zebrafish offspring development and lifelong fitness
Jimenez-Gonzalez, A., Ansaloni, F., Nebendahl, C., Aalavioon, G., Murray, D., Robak, W., Sanges, R., Müller, F. & Immler, S., Mar 2024, In: Molecular Ecology. 33, 6, e17296.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Erratum: Fasting increases investment in soma upon refeeding at the cost of gamete quality in zebrafish (2023) (Proc. R. Soc. B (2023) 290 (20221556) DOI: 10.1098/rspb.2022.1556)
Ivimey-Cook, E. R., Murray, D. S., de Coriolis, J. C., Edden, N., Immler, S. & Maklakov, A. A., 3 May 2023, In: Proceedings of the Royal Society B: Biological Sciences. 290, 1998, 20230872.Research output: Contribution to journal › Comment/debate › peer-review
Open Access
Press/Media
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IVF: here’s how genetics may be affecting its success – new insights
30/05/22
1 Media contribution
Press/Media: Media Coverage or Contribution
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Study finds ‘old’ sperm produces healthier offspring
17/02/19
1 item of Media coverage
Press/Media: Media Coverage or Contribution
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Women's bodies BLOCK weak sperm by creating a 'bottleneck' in the uterus where stronger swimmers force their way through
14/02/19
1 item of Media coverage
Press/Media: Media Coverage or Contribution
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'Old' sperm produces healthier offspring
14/02/19
1 item of Media coverage
Press/Media: UEA Press Release
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Offspring from older sperm are fitter and age more slowly
14/02/19
1 item of Media coverage
Press/Media: Media Coverage or Contribution