Projects per year
Personal profile
Biography
During my PhD in the School of Medicine (UEA) with Dr Silke Schelenz, I focused on understanding how soluble immune receptors found in the lungs and bloodstream could recognise and protect against pathogenic fungi. Following my PhD, I made the move north to sunny Aberdeen and under the guidance of Prof. Gordon Brown helped characterise the first receptor for melanin. Here, we found that this receptor was critical for antifungal immunity in humans and mice. I made a return to UEA in 2016 where I have focused on characterising novel allosteric modulators of purinergic receptors and understanding their biological roles (Dr. Leanne Stokes and Prof. Samuel Fountain). I have since recently been appointed as Lecturer in Pharmacology in the School of Pharmacy where I will endeavour to understand how the human body detects and responds to invasion by fungal pathogens, identify novel drug targets to overcome antifungal resistance, and explore how to prevent inflammation-driven diseases.
My experience is widely varied and encompasses host-microbe interactions, microbial genomics, nucleic acids biology, biophysics, drug discovery, cell death, cardiovascular biology, immune cell receptors, in-silico modelling, bioinformatics, and chemical biology.
Career
- Lecturer of Pharmacology, University of East Anglia (2022 - present)
- Senior Research Associate (BHF), University of East Anglia (2020 - 2022)
- Senior Research Associate (BBSRC), University of East Anglia (2016 - 2019)
- Research Associate (Wellcome Trust), University of Aberdeen (2014 - 2016)
- PhD in Biomedical Sciences, University of East Anglia (2011 - 2015)
- BSc (Hons) Genetics and Molecular Biology, University of East Anglia (2008 - 2011)
Collaborations and top research areas from the last five years
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Four-stranded fungal fatality: Unveiling G-quadruplexes as future antifungal targets
Bidula, S. & Macdonald, C.
Biotechnology and Biological Sciences Research Council
3/06/24 → 2/06/27
Project: Research
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Exploring the contribution of secondary metabolites to fungal immune evasion
1/12/23 → 31/05/25
Project: Research
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Discovery of novel secondary metabolites from marine organisms
Royal Embassy of Saudi Arabia Cultural Bureau, London
1/10/23 → 30/09/24
Project: Training
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Targeting G-quadruplexes to modulate secondary metabolite production in Aspergillus spp.
1/09/23 → 31/08/25
Project: Research
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Identifying new drugs to treat secondary fungal infections in cancer
17/06/24 → 11/08/24
Project: Research
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Piezo1-mediated regulation of smooth muscle cell volume in response to enhanced extracellular matrix rigidity
Johnson, R. T., Solanki, R., Wostear, F., Ahmed, S., Taylor, J. C. K., Rees, J., Abel, G., McColl, J., Jørgensen, H. F., Morris, C. J., Bidula, S. & Warren, D. T., Jun 2024, In: British Journal of Pharmacology. 181, 11, p. 1576-1595 20 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)8 Downloads (Pure) -
Genomic analysis of non-B nucleic acids structures in SARS-CoV-2: Potential key roles for these structures in mutability, translation, and replication?
Bidula, S. & Brázda, V., 6 Jan 2023, In: Genes. 14, 1, 157.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)8 Downloads (Pure) -
Variability of inverted repeats in all available genomes of bacteria
Porubiaková, O., Havlík, J., Indu, Šedý, M., Přepechalová, V., Bartas, M., Bidula, S., Šťastný, J., Fojta, M. & Brázda, V., 17 Aug 2023, In: Microbiology Spectrum. 11, 4, e01648-23.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)3 Downloads (Pure) -
Conservation and over-representation of G-quadruplex sequences in regulatory regions of mitochondrial DNA across distinct taxonomic sub-groups
Bohálová, N., Dobrovolná, M., Brázda, V. & Bidula, S., Mar 2022, In: Biochimie. 194, p. 28-34 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Downloads (Pure) -
Inverted repeats in the monkeypox virus genome are hot spots for mutation
Dobrovolná, M., Brázda, V., Warner, E. F. & Bidula, S., 3 Dec 2022, In: Journal of Medical Virology. 95, 1, e28322.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Citations (Scopus)7 Downloads (Pure)
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Virulence (Journal)
Stefan Bidula (Associate Editor)
18 May 2022 → …Activity: Editorial work › Publication editorial role
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Frontiers in Aging (Journal)
Stefan Bidula (Guest editor)
2022 → …Activity: Editorial work › Publication editorial role
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Frontiers in Immunology (Journal)
Stefan Bidula (Guest editor)
13 Jul 2021 → …Activity: Editorial work › Publication editorial role
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Critical Reviews in Microbiology (Journal)
Stefan Bidula (Associate Editor)
30 Nov 2020 → …Activity: Editorial work › Publication editorial role
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Freelance Manuscript Copyeditor
Stefan Bidula (Contributor)
2020 → …Activity: Other activity types › Other