Stephen Laycock

Search results

• 2025

  Interactive docking workshop: Docking the anticancer drug Belinostat to its cellular histone deacetylase (HDAC) target

  Iakovou, G., Palmer, L., Ganesan, A., Kitao, A., Laycock, S. D. & Hayward, S., 10 Jun 2025, In: Journal of Chemical Education. 102, 6, p. 2514–2521 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Protein domain movement involved in binding of belinostat and HPOB as inhibitors of histone deacetylase 6 (HDAC6): a hybrid automated-interactive docking study

  Iakovou, G., Palmer, L., Ganesan, A., Kitao, A., Laycock, S. D. & Hayward, S., 15 Jul 2025, In: Journal of Computer-Aided Molecular Design. 39, 52.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  2 Downloads (Pure)
• 2022

  Interactive flexible-receptor molecular docking in VR using DockIT

  Iakovou, G., Laycock, S. D. & Hayward, S., 12 Dec 2022, In: Journal of Chemical Information and Modeling. 62, 23, p. 5855–5861 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  9 Citations (Scopus)

  19 Downloads (Pure)
• 2021

  Software Introduction: Methodological advances for interacting with biomolecules using haptics

  Iakovou, G., Laycock, S. & Hayward, S., Oct 2021, In: Ensemble. 23, 4, p. 283-289 7 p.

  Research output: Contribution to journal › Article

  Open Access

  File
  27 Downloads (Pure)
• 2020

  DockIT: A tool for interactive molecular docking and molecular complex construction

  Iakovou, G., Alhazzazi, M., Hayward, S. & Laycock, S. D., 15 Dec 2020, In: Bioinformatics. 36, 24, p. 5698–5700 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  8 Citations (Scopus)
• 2019

  Combining computer vision and deep learning to enable ultra-scale aerial phenotyping and precision agriculture: A case study of lettuce production

  Bauer, A., Bostrom, A. G., Ball, J., Applegate, C., Cheng, T., Laycock, S., Rojas, S. M., Kirwan, J. & Zhou, J., 1 Jun 2019, In: Horticulture Research. 2019, 6, p. 1-12 12 p., 70.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  126 Citations (Scopus)

  42 Downloads (Pure)

• Haptic-assisted interactive molecular docking incorporating receptor flexibility

  Matthews, N., Kitao, A., Laycock, S. & Hayward, S., 24 Jun 2019, In: Journal of Chemical Information and Modeling. 59, 6, p. 2900-2912 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  14 Citations (Scopus)

  32 Downloads (Pure)

• Smart system for prediction of accurate surface electromyography signals using an artificial neural network

  Dorgham, O., Al-Mherat, I., Al-Shaer, J., Bani-Ahmad, S. & Laycock, S., Jan 2019, In: Future Internet. 11, 1, 25.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  13 Citations (Scopus)

  22 Downloads (Pure)
• 2017

  High quality rendering of protein dynamics in space filling mode

  Matthews, N., Easdon, R., Kitao, A., Hayward, S. & Laycock, S., Nov 2017, In: Journal of Molecular Graphics and Modelling. 78, p. 158-167 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  4 Citations (Scopus)

  17 Downloads (Pure)

• Virtual environment for studying the docking interactions of rigid biomolecules with haptics

  Iakovou, G., Hayward, S. & Laycock, S., 22 May 2017, In: Journal of Chemical Information and Modeling. 57, 5, p. 1142–1152 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  12 Citations (Scopus)

  18 Downloads (Pure)
• 2016

  Determination of locked interfaces in biomolecular complexes using Haptimol_RD

  Iakovou, G., Laycock, S. & Hayward, S., 14 Jul 2016, In: Biophysics and Physicobiology. 13, p. 97-103 7 p.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)
• 2015

  Adaptive GPU-accelerated force calculation for interactive rigid molecular docking using haptics

  Iakovou, G., Hayward, S. & Laycock, S. D., Sept 2015, In: Journal of Molecular Graphics and Modelling. 61, p. 1-12 12 p.

  Research output: Contribution to journal › Article › peer-review

  File
  11 Citations (Scopus)

  29 Downloads (Pure)

• Towards the production of radiotherapy treatment shells on 3D printers using data derived from DICOM CT and MRI: preclinical feasibility studies

  Laycock, S. D., Hulse, M., Scrase, C. D., Tam, M. D., Isherwood, S., Mortimore, D. B., Emmens, D., Patman, J., Short, S. C. & Bell, G. D., Mar 2015, In: Journal of Radiotherapy in Practice. 14, 01, p. 92-98 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  31 Citations (Scopus)

  18 Downloads (Pure)

• Using a combination of micro-computed tomography, CAD and 3D printing techniques to reconstruct incomplete 19th-century Cantonese chess pieces

  Laycock, S. D., Bell, G. D., Corps, N., Mortimore, D. B., Cox, G., May, S. & Finkel, I., 11 Feb 2015, In: Journal on Computing and Cultural Heritage. 7, 4, 25.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  21 Citations (Scopus)

  20 Downloads (Pure)
• 2014

  3-D visualisation, printing, and volume determination of the tracheal respiratory system in the adult desert locust, Schistocerca gregaria

  Greco, M., Bell, D., Woolnough, L., Laycock, S., Corps, N., Mortimore, D. & Hudson, D., 1 Jul 2014, In: Entomologia Experimentalis et Applicata. 152, 1, p. 42-51

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  16 Citations (Scopus)

  57 Downloads (Pure)

• A real-time proximity querying algorithm for haptic-based molecular docking

  Iakovou, G., Hayward, S. & Laycock, S., 3 May 2014, In: Faraday Discussions. 169, p. 359-377 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  10 Citations (Scopus)

  22 Downloads (Pure)

• Augmenting graphical user interfaces with haptic assistance for motion-impaired operators

  Asque, C., Day, A. & Laycock, S., 2014, In: International Journal of Human-Computer Studies. 72, 10-11, p. 689-703 15 p.

  Research output: Contribution to journal › Article › peer-review

  File
  5 Citations (Scopus)

  46 Downloads (Pure)

• Evaluation of 3D printed immobilisation shells for head and neck IMRT

  Fisher, M., Applegate, C., Ryalat, M., Laycock, S., Hulse, M., Emmens, D. & Bell, D., 2014, In: Open Journal of Radiology. 04, 04, p. 322-328 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  37 Downloads (Pure)

• Real-time accumulation of occlusion-based snow

  Reynolds, D. T., Laycock, S. D. & Day, A. M., Jun 2014, In: The Visual Computer. 31, p. 689-700

  Research output: Contribution to journal › Article › peer-review
  9 Citations (Scopus)
• 2013

  3D printing of an aortic aneurysm to facilitate decision making and device selection for endovascular aneurysm repair in complex neck anatomy

  Tam, M. D. B. S., Laycock, S. D., Brown, J. R. I. & Jakeways, M., 1 Dec 2013, In: Journal of Endovascular Therapy. 20, 6, p. 863-867 5 p.

  Research output: Contribution to journal › Article › peer-review
  110 Citations (Scopus)

• 3-D printouts of the tracheobronchial tree generated from CT DICOM files as an aid to planning future interventional management in a case of extensive tracheobronchial chondromalacia caused by advanced relapsing polychondritis

  Tam, M. D. B. S., Laycock, S., Jayne, D., Babar, J. & Noble, B., 2013, In: Journal of Radiology Case Reports. 7, 8, p. 34-43

  Research output: Contribution to journal › Article › peer-review
  30 Citations (Scopus)

• Fast reconstructed radiographs from Octree compressed volumetric data

  Fisher, M., Dorgham, O. & Laycock, S., Mar 2013, In: International Journal of Computer Assisted Radiology and Surgery. 8, 2, p. 313-322 10 p.

  Research output: Contribution to journal › Article › peer-review
  15 Citations (Scopus)
• 2012

  3-D printout of a DICOM file to aid surgical planning in a 6 year old patient with a large scapular osteochondroma complicating congenital diaphyseal aclasia

  Tam, M., Laycock, S., Bell, D. & Chojnowski, A., Jan 2012, In: Journal of Radiology Case Reports. 6, 1, p. 31-37 7 p.

  Research output: Contribution to journal › Article › peer-review
  97 Citations (Scopus)

• A sketch-based system for highway design with user-specified regions of influence

  Applegate, C. S., Laycock, S. D. & Day, A. M., Oct 2012, In: Computers & Graphics. 36, 6, p. 685-695 11 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• Combining X-ray micro-CT technology and 3D printing for the digital preservation and study of a 19th century cantonese chess piece with intricate internal structure

  Laycock, S. D., Bell, G. D., Mortimore, D. B., Greco, M. K., Corps, N. & Finkle, I., Dec 2012, In: Journal on Computing and Cultural Heritage. 5, 4, p. 13:1-13:7

  Research output: Contribution to journal › Article › peer-review
  21 Citations (Scopus)

• GPU accelerated generation of digitally reconstructed radiographs for 2D/3D image registration

  Dorgham, O. M., Laycock, S. D. & Fisher, M. H., 2012, In: IEEE Transactions on Biomedical Engineering. 59, 9, p. 2594-2603 10 p.

  Research output: Contribution to journal › Article › peer-review
  51 Citations (Scopus)

• Haptic assisted target acquisition in a visual point-and-click task for computer users with motion-impairments

  Asque, C. T., Day, A. M. & Laycock, S. D., 2012, In: IEEE Transactions on Haptics. 5, 2, p. 120-130 11 p.

  Research output: Contribution to journal › Article › peer-review
  9 Citations (Scopus)
• 2011

  Aligning archive maps and extracting footprints for analysis of historic urban environments.

  Laycock, S., Brown, P., Laycock, R. & Day, A., Apr 2011, In: Computers & Graphics. 35, 2, p. 242-249 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  23 Citations (Scopus)

  19 Downloads (Pure)

• Applying forces to elastic network models of large biomolecules using a haptic feedback device

  Stocks, M., Laycock, S. & Hayward, S., Mar 2011, In: Journal of Computer-Aided Molecular Design. 25, 3, p. 203-211 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  10 Citations (Scopus)

  20 Downloads (Pure)
• 2010

  Fast 2D/3D Image Registration using Accelerated Generation of Sparsely Rendered Digitally Reconstructed Radiographs

  Dorgham, O., Fisher, M., Laycock, S., Vinall, A. J. & Holmes-Smith, W., 2010, In: International Journal of Computer Assisted Radiology and Surgery. 5, S1, p. S68

  Research output: Contribution to journal › Article › peer-review
• 2009

  Interacting with the biomolecular solvent accessible surface via a haptic feedback device

  Stocks, M. B., Hayward, S. & Laycock, S. D., 27 Oct 2009, In: BMC Structural Biology. 9, 69.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  22 Citations (Scopus)

  23 Downloads (Pure)
• 2008

  Performance of 2D-3D image registration using (lossy) compressed X-ray CT

  Dorgham, O., Fisher, M. & Laycock, S. D., 2008, In: Annals of the BMVA. 2009, 3, p. 1-11 11 p.

  Research output: Contribution to journal › Article › peer-review
• 2007

  A distance hierarchy to detect collisions between deformable objects

  Madera, F. A., Day, A. M. & Laycock, S. D., Jun 2007, In: Theory and Practice of Computer Graphics. p. 53-60 8 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• A survey of haptic rendering techniques

  Laycock, S. D. & Day, A. M., Mar 2007, In: Computer Graphics Forum. 26, 1, p. 50-65 16 p.

  Research output: Contribution to journal › Article › peer-review
  80 Citations (Scopus)
• 2005

  Incorporating haptic feedback for the simulation of a deformable tool in a rigid scene

  Laycock, S. D. & Day, A. M., Jun 2005, In: Computers & Graphics. 29, 3, p. 341-351 11 p.

  Research output: Contribution to journal › Article › peer-review
  13 Citations (Scopus)
• 2004

  Introducing a novel haptic interface for the planning and simulation of open surgery

  Lapeer, R. J., Gasson, P., Florens, J-L., Laycock, S. D. & Karri, V., 2004, In: Studies in Health Technology and Informatics. 98, p. 197-199 3 p.

  Research output: Contribution to journal › Article
  7 Citations (Scopus)
• 2003

  Recent developments and applications of haptic devices

  Laycock, S. D. & Day, A. M., 2003, In: Computer Graphics Forum. 22, 2, p. 117-132 16 p.

  Research output: Contribution to journal › Article
  112 Citations (Scopus)

• The haptic rendering of polygonal models involving deformable tools

  Laycock, SD. & Day, AM., 2003, In: Eurohaptics. p. 176-192 17 p.

  Research output: Contribution to journal › Article › peer-review