Stephen Robinson

Search results

• 2023

  Allocoprobacillus halotolerans gen. nov., sp. nov and Coprobacter tertius sp. nov., isolated from human gut microbiota

  Teng, N. M. Y., Kiu, R., Evans, R., Baker, D. J., Zenner, C., Robinson, S. D. & Hall, L. J., 6 Jul 2023, In: International Journal of Systematic and Evolutionary Microbiology. 73, 7, 005950.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  8 Downloads (Pure)

• Particular genomic and virulence traits associated with preterm infant-derived toxigenic Clostridium perfringens strains

  Kiu, R., Shaw, A. G., Sim, K., Acuna-Gonzalez, A., Price, C. A., Bedwell, H., Dreger, S. A., Fowler, W. J., Cornwell, E., Pickard, D., Belteki, G., Malsom, J., Phillips, S., Young, G. R., Schofield, Z., Alcon-Giner, C., Berrington, J. E., Stewart, C. J., Dougan, G., Clarke, P. & 4 others, Douce, G., Robinson, S. D., Kroll, J. S. & Hall, L. J., 25 May 2023, In: Nature Microbiology. 8, 6, p. 1160-1175 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  15 Citations (Scopus)

  9 Downloads (Pure)
• 2022

  Endothelial VEGFR coreceptors neuropilin-1 and neuropilin-2 are essential for tumor angiogenesis

  Benwell, C. J., Johnson, R. T., Taylor, J. A. G. E., Price, C. A. & Robinson, S. D., Dec 2022, In: Cancer Research Communications. 2, 12, p. 1626–1640 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  10 Citations (Scopus)

  13 Downloads (Pure)

• Reciprocal interactions between the gut microbiome and mammary tissue mast cells promote metastatic dissemination of HR+ breast tumors

  Feng, T-Y., Azar, F. N., Dreger, S. A., Rosean, C. B., McGinty, M. T., Putelo, A. M., Kolli, S. H., Carey, M. A., Greenfield, S., Fowler, W. J., Robinson, S. D. & Rutkowski, M. R., 1 Nov 2022, In: Cancer Immunology Research. 10, 11, p. 1309–1325 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  7 Citations (Scopus)

• Using Immortalized Endothelial Cells to Study the Roles of Adhesion Molecules in VEGF-Induced Signaling

  Taylor, J. A. G. E., Benwell, C. J. & Robinson, S. D., 2022, VEGF Signaling: Methods and Protocols. Fiedler, L. R. & Pellet-Many, C. (eds.). Humana Press Inc, p. 133-141 9 p. (Methods in Molecular Biology; vol. 2475).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
• 2021

  Antibiotic-induced disturbances of the gut microbiota result in accelerated breast tumor growth

  McKee, A. M., Kirkup, B. M., Madgwick, M., Fowler, W. J., Price, C. A., Dreger, S. A., Ansorge, R., Makin, K. A., Caim, S., Le Gall, G., Paveley, J., Leclaire, C., Dalby, M. J., Alcon-Giner, C., Andrusaite, A., Feng, T-Y., Di Modica, M., Triulzi, T., Tagliabue, E., Milling, S. W. F. & 5 others, Weilbaecher, K. N., Rutkowski, M. R., Korcsmaros, T., Hall, L. J. & Robinson, S. D., 24 Sep 2021, In: iScience. 24, 9, 103012.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  40 Citations (Scopus)

  20 Downloads (Pure)

• Bacterial strains augment cancer therapeutics

  Hall, L. & Robinson, S., Mar 2021, In: Nature Microbiology. 6, 3, p. 275-276 2 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Endothelial neuropilin‐2 influences angiogenesis by regulating actin pattern development and α5‐integrin‐ p ‐FAK complex recruitment to assembling adhesion sites

  Benwell, C. J., Taylor, J. A. G. E. & Robinson, S. D., 27 Aug 2021, In: The FASEB Journal. 35, 8, e21679.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  8 Citations (Scopus)

  25 Downloads (Pure)

• Exploring the impact of gut microbiota and diet on breast cancer risk and progression

  Teng, N., Price, C., Mckee, A., Hall, L. & Robinson, S., 1 Aug 2021, In: International Journal of Cancer. 149, 3, p. 494-504 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  22 Citations (Scopus)

  24 Downloads (Pure)
• 2020

  ADAMTS-1 and Syndecan-4 intersect in the regulation of cell migration and angiogenesis

  Lambert, J., Makin, K., Akbareian, S., Johnson, R., Alghamdi, A., Robinson, S. & Edwards, D., 8 Apr 2020, In: Journal of Cell Science. 133, 7, jcs235762.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  32 Citations (Scopus)

  14 Downloads (Pure)

• Cancer burden is controlled by mural cell-β3-integrin regulated crosstalk with tumor cells

  Wong, P-P., Munoz-Felix, J. M., Hijazi, M., Kim, H., Robinson, S., De Luxan-Delgado, B., Rodiguez-Hernandez, I., Maiques, O., Meng, Y-M., Meng, Q., Bodrug, N., Dukinfield, M. S., Reynolds, L. E., Elia, G., Clear, A., Harwood, C., Wang, Y., Campbell, J. J., Singh, R., Zhang, P. & 12 others, Schall, T. J., Matchett, K. P., Henderson, N., Szlosarek, P. W., Dreger, S., Smith, S., Jones, L., Gribben, J. G., Cutillas, P. R., Meier, P., Sanz-Moreno, V. & Hodivala-Dilke, K., 11 Jun 2020, In: Cell. 181, 6, p. 1346-1363.e21 18 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  56 Citations (Scopus)

  11 Downloads (Pure)

• NRP2 as an emerging angiogenic player; promoting endothelial cell adhesion and migration by regulating recycling of α5 integrin

  Alghamdi, A., Benwell, C., Atkinson, S., Lambert, J., Johnson, R. & Robinson, S., 26 May 2020, In: Frontiers in Cell and Developmental Biology. 8, 395.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  29 Citations (Scopus)

  20 Downloads (Pure)
• 2019

  The microbiota, antibiotics and breast cancer

  McKee, A. M., Hall, L. J. & Robinson, S. D., Nov 2019, In: Breast Cancer Management. 8, 3, 3 p., 29.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access
  7 Citations (Scopus)
• 2018

  HIF1α drives chemokine factor pro-tumoral signaling pathways in acute myeloid leukemia

  Abdul-Aziz, A. M., Shafat, M. S., Sun, Y., Marlein, C. R., Piddock, R. E., Robinson, S. D., Edwards, D. R., Zhou, Z., Collins, A., Bowles, K. M. & Rushworth, S. A., 2018, In: Oncogene. 37, p. 2676–2686 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  21 Citations (Scopus)

  28 Downloads (Pure)

• The anti-rheumatic drug, leflunomide, synergizes with MEK inhibition to suppress melanoma growth

  Hanson, K., Robinson, S., Al-Yousuf, K., Hendry, A., Sexton, D., Sherwood, V. & Wheeler, G., 2018, In: Oncotarget. 9, p. 3815-3829

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  16 Citations (Scopus)

  32 Downloads (Pure)

• The β3‐integrin endothelial adhesome regulates microtubule‐dependent cell migration

  Atkinson, S. J., Gontarczyk, A. M., Alghamdi, A. A. A., Ellison, T. S., Johnson, R. T., Fowler, W. J., Kirkup, B. M., Silva, B. C., Harry, B. E., Schneider, J. G., Weilbaecher, K. N., Mogensen, M. M., Bass, M. D., Parsons, M., Edwards, D. R. & Robinson, S. D., 1 Jun 2018, In: EMBO Reports. 19, 6, e44578.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  18 Citations (Scopus)

  31 Downloads (Pure)
• 2017

  Leukemic blasts program bone marrow adipocytes to generate a protumoral microenvironment

  Shafat, M. S., Oellerich, T., Mohr, S., Robinson, S. D., Edwards, D. R., Marlein, C. R., Piddock, R. E., Fenech, M., Zaitseva, L., Abdul-Aziz, A., Turner, J., Watkins, J. A., Lawes, M., Bowles, K. M. & Rushworth, S. A., 9 Mar 2017, In: Blood. 129, 10, p. 1320-1332 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  241 Citations (Scopus)

  16 Downloads (Pure)

• NADPH oxidase-2 derived superoxide drives mitochondrial transfer from bone marrow stromal cells to leukemic blasts

  Marlein, C. R., Zaitseva, L., Piddock, R. E., Robinson, S., Edwards, D., Shafat, M. S., Zhou, Z., Lawes, M., Bowles, K. M. & Rushworth, S. A., 5 Oct 2017, In: Blood. 130, 14, p. 1649-1660 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  236 Citations (Scopus)

  17 Downloads (Pure)

• PI3Kδ and PI3Kγ isoforms have distinct functions in regulating pro-tumoural signalling in the multiple myeloma microenvironment

  Piddock, R. E., Loughran, N., Marlein, C. R., Robinson, S. D., Edwards, D. R., Yu, S., Pillinger, G. E., Zhou, Z., Zaitseva, L., Auger, M. J., Rushworth, S. A. & Bowles, K. M., 10 Mar 2017, In: Blood Cancer Journal. 7, 3, e539.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  24 Citations (Scopus)

  26 Downloads (Pure)

• Sulforaphane exerts anti-angiogenesis effects against hepatocellular carcinoma through inhibition of STAT3/HIF-1α/VEGF signalling

  Liu, P., Atkinson, S. J., Akbareian, S., Zhou, Z., Munsterberg, A., Robinson, S. & Bao, Y., 4 Oct 2017, In: Scientific Reports. 7, 12651.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  85 Citations (Scopus)

  24 Downloads (Pure)
• 2016

  Antagonizing integrin β3 increases immunosuppression in cancer

  Su, X., Esser, A. K., Amend, S. R., Xiang, J., Ross, M. H., Fox, G. C., Kobayashi, T., Steri, V., Roomp, K., Fontana, F., Hurchla, M. A., Knolhoff, B. L., Meyer, M. A., Morgan, E. A., Tomasson, J. C., Novack, J. S., Zou, W., Faccio, R., Novack, D. V., Robinson, S. D. & 4 others, Teitelbaum, S. L., DeNardo, D. G., Schneider, J. G. & Weilbaecher, K. N., 15 Jun 2016, In: Cancer Research. 76, 12, p. 3484-3495 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  56 Citations (Scopus)

  10 Downloads (Pure)
• 2015

  Metalloproteinase-dependent and -independent processes contribute to inhibition of breast cancer cell migration, angiogenesis and liver metastasis by a disintegrin and metalloproteinase with thrombospondin motifs-15

  Kelwick, R., Wagstaff, L., Decock, J., Roghi, C., Cooley, L. S., Robinson, S. D., Arnold, H., Gavrilovic, J., Jaworski, D. M., Yamamoto, K., Nagase, H., Seubert, B., Krüger, A. & Edwards, D. R., 15 Feb 2015, In: International Journal of Cancer. 136, 4, p. E14–E26

  Research output: Contribution to journal › Article › peer-review
  43 Citations (Scopus)

• Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice

  Decock, J., Hendrickx, W., Thirkettle, S., Gutiérrez-Fernández, A., Robinson, S. D. & Edwards, D. R., 14 Mar 2015, In: Breast Cancer Research. 17, 1, 38.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  32 Citations (Scopus)

  17 Downloads (Pure)

• Suppression of β3-integrin in mice triggers a neuropilin-1- dependent change in focal adhesion remodelling that can be targeted to block pathological angiogenesis

  Ellison, T. S., Atkinson, S. J., Steri, V., Kirkup, B. M., Preedy, M. E. J., Johnson, R. T., Ruhrberg, C., Edwards, D. R., Schneider, J. G., Weilbaecher, K. & Robinson, S. D., 1 Sep 2015, In: Disease Models & Mechanisms. 8, p. 1105-1119 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  19 Citations (Scopus)

  15 Downloads (Pure)
• 2014

  Acute depletion of endothelial β3-integrin transiently inhibits tumor growth and angiogenesis in mice

  Steri, V., Ellison, T. S., Gontarczyk, A. M., Weilbaecher, K., Schneider, J. G., Edwards, D., Fruttiger, M., Hodivala-Dilke, K. M. & Robinson, S. D., 3 Jan 2014, In: Circulation Research. 114, 1, p. 79-91 13 p.

  Research output: Contribution to journal › Article › peer-review
  35 Citations (Scopus)

• Generation of point-mutant FAK knockin mice

  Tavora, B., Batista, S., Alexopoulou, A. N., Kostourou, V., Fernandez, I., Robinson, S. D., Lees, D. M., Serrels, B. & Hodivala-Dilke, K., 1 Nov 2014, In: genesis. 52, 11, p. 907-915 9 p.

  Research output: Contribution to journal › Article › peer-review
  8 Citations (Scopus)
• 2013

  Endogenous ribosomal protein L29 (RPL29): a newly identified regulator of angiogenesis in mice

  Jones, D. T., Lechertier, T., Reynolds, L. E., Mitter, R., Robinson, S., Kirn-Safran, C. B., Hodivala-Dilke, K. M. & Robinson, S., Jan 2013, In: Disease Models & Mechanisms. 6, 1, p. 115-24 10 p.

  Research output: Contribution to journal › Article › peer-review
  15 Citations (Scopus)

• FAK-heterozygous mice display enhanced tumour angiogenesis

  Kostourou, V., Lechertier, T., Reynolds, L. E., Lees, D. M., Baker, M., Jones, D. T., Tavora, B., Ramjuan, A. R., Birdsey, G. M., Robinson, S. R., Parsons, M., Randi, A. M., Hart, I. R. & Hodivala-Dilke, K., 25 Jun 2013, In: Nature Communications. 4, 2020.

  Research output: Contribution to journal › Article › peer-review
  37 Citations (Scopus)

• Stromal Claudin14-heterozygosity, but not deletion, increases tumour blood leakage without affecting tumour growth

  Baker, M., Reynolds, L. E., Robinson, S. D., Lees, D. M., Parsons, M., Elia, G. & Hodivala-Dilke, K. M., 13 May 2013, In: PLoS One. 8, 5, e62516.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  14 Citations (Scopus)
• 2012

  Use of the mouse aortic ring assay to study angiogenesis

  Baker, M., Robinson, S., Lechertier, T., Barber, P. R., Tavora, B., D'Amico, G., Jones, D. T., Vojnovic, B. & Hodivala-Dilke, K., Jan 2012, In: Nature Protocols. 7, 1, p. 89-104 16 p.

  Research output: Contribution to journal › Article › peer-review
  383 Citations (Scopus)
• 2011

  The role of β3-integrins in tumor angiogenesis: context is everything

  Robinson, S. D. & Hodivala-Dilke, K. M., Oct 2011, In: Current Opinion in Cell Biology. 23, 5, p. 630-637 8 p.

  Research output: Contribution to journal › Article › peer-review
  111 Citations (Scopus)
• 2010

  Alpha v 3 integrin spatially regulates VASP and RIAM to control adhesion dynamics and migration

  Worth, D. C., Hodivala-Dilke, K., Robinson, S. D., King, S. J., Morton, P. E., Gertler, F. B., Humphries, M. J. & Parsons, M., 19 Apr 2010, In: Journal of Cell Biology. 189, 2, p. 369-383 15 p.

  Research output: Contribution to journal › Article › peer-review
  67 Citations (Scopus)

• Endothelial FAK is required for tumour angiogenesis

  Tavora, B., Batista, S., Reynolds, L. E., Jadeja, S., Robinson, S. D., Kostourou, V., Hart, I., Fruttiger, M., Parsons, M. & Hodivala-Dilke, K. M., Dec 2010, In: EMBO Molecular Medicine. 2, 12, p. 516-528 13 p.

  Research output: Contribution to journal › Article › peer-review
  117 Citations (Scopus)

• Endothelial-Rac1 is not required for tumor angiogenesis unless αvβ3-integrin is absent

  D'Amico, G., Robinson, S. D., Germain, M., Reynolds, L. E., Thomas, G. J., Elia, G., Saunders, G., Fruttiger, M., Tybulewicz, V., Mavria, G. & Hodivala-Dilke, K. M., 22 Mar 2010, In: PLoS One. 5, 3, e9766.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  22 Citations (Scopus)

• Endothelial α3β1-integrin represses pathological angiogenesis and sustains endothelial-VEGF

  da Silva, R. G., Tavora, B., Robinson, S. D., Reynolds, L. E., Szekeres, C., Lamar, J., Batista, S., Kostourou, V., Germain, M. A., Reynolds, A. R., Jones, D. T., Watson, A. R., Jones, J. L., Harris, A., Hart, I. R., Iruela-Arispe, M. L., DiPersio, C. M., Kreidberg, J. A. & Hodivala-Dilke, K. M., Sep 2010, In: American Journal of Pathology. 177, 3, p. 1534-1548 15 p.

  Research output: Contribution to journal › Article › peer-review
  54 Citations (Scopus)

• Genetic ablation of the alpha 6-integrin subunit in Tie1Cre mice enhances tumour angiogenesis

  Germain, M., De Arcangelis, A., Robinson, S. D., Baker, M., Tavora, B., D'Amico, G., Silva, R., Kostourou, V., Reynolds, L. E., Watson, A., Jones, J. L., Georges-Labouesse, E. & Hodivala-Dilke, K., Feb 2010, In: The Journal of Pathology. 220, 3, p. 370-381 12 p.

  Research output: Contribution to journal › Article › peer-review
  30 Citations (Scopus)

• Tumour angiogenesis is reduced in the Tc1 mouse model of Down’s syndrome

  Reynolds, L. E., Watson, A. R., Baker, M., Jones, T. A., D’Amico, G., Robinson, S. D., Joffre, C., Garrido-Urbani, S., Rodriguez-Manzaneque, J. C., Martino-Echarri, E., Aurrand-Lions, M., Sheer, D., Dagna-Bricarelli, F., Nizetic, D., McCabe, C. J., Turnell, A. S., Kermorgant, S., Imhof, B. A., Adams, R., Fisher, E. M. C. & 3 others, Tybulewicz, V. L. J., Hart, I. R. & Hodivala-Dilke, K. M., 10 Jun 2010, In: Nature. 465, 7299, p. 813-817 5 p.

  Research output: Contribution to journal › Article › peer-review
  108 Citations (Scopus)
• 2009

  avβ3 Integrin limits the contribution of neuropilin-1 to vascular endothelial growth factor-induced angiogenesis

  Robinson, S. D., Reynolds, L. E., Kostourou, V., Reynolds, A. R., da Silva, R. G., Tavora, B., Baker, M., Marshall, J. F. & Hodivala-Dilke, K. M., 4 Dec 2009, In: Journal of Biological Chemistry. 284, 49, p. 33966-33981 16 p.

  Research output: Contribution to journal › Article › peer-review
  82 Citations (Scopus)

• Regulation of lymphatic-blood vessel separation by endothelial Rac1

  D'Amico, G., Jones, D. T., Nye, E., Sapienza, K., Ramjuan, A. R., Reynolds, L. E., Robinson, S. D., Kostourou, V., Martinez, D., Aubyn, D., Grose, R., Thomas, G. J., Spencer-Dene, B., Zicha, D., Davies, D., Tybulewicz, V. & Hodivala-Dilke, K. M., 1 Dec 2009, In: Development. 136, 23, p. 4043-4053 11 p.

  Research output: Contribution to journal › Article › peer-review
  37 Citations (Scopus)

• Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors

  Reynolds, A. R., Hart, I. R., Watson, A. R., Welti, J. C., Silva, R. G., Robinson, S. D., Da Violante, G., Gourlaouen, M., Salih, M., Jones, M. C., Jones, D. T., Saunders, G., Kostourou, V., Perron-Sierra, F., Norman, J. C., Tucker, G. C. & Hodivala-Dilke, K. M., Mar 2009, In: Nature Medicine. 15, 4, p. 392-400 9 p.

  Research output: Contribution to journal › Article › peer-review
  406 Citations (Scopus)
• 2008

  α3β1 integrin–controlled Smad7 regulates reepithelialization during wound healing in mice

  Reynolds, L. E., Conti, F. J., Silva, R., Robinson, S. D., Iyer, V., Rudling, R., Cross, B., Nye, E., Hart, I. R., DiPersio, C. M. & Hodivala-Dilke, K. M., 3 Mar 2008, In: Journal of Clinical Investigation. 118, 3, p. 965-974 10 p.

  Research output: Contribution to journal › Article › peer-review
  82 Citations (Scopus)