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Personal profile

Biography

 

Susan gained her BPharm from the University of Nottingham in 1991, qualified as a Pharmacist (RPSGB) in 1992 before receiving her PhD in Medicinal Chemistry, from the University of Bath in 1995 for a thesis entitled "Synthesis of Biodegradable Polymers for Delivery of Diagnostic Agents". She gained Post-Doctoral experience at the Institute of Macromolecular Chemistry, Prague (Royal Society European Fellowship), Johannes Gutenberg Universität, Mainz and the Inorganic Chemistry Laboratory, Oxford before taking up the Kinerton Lectureship of Organic Chemistry at Trinity College, Dublin.  She joined the School in April 2003 as Lecturer of Medicinal Chemistry and was promoted to Senior lecturer in 2008.

She is currently the Chair of the University South East Asia Dialogue Group and was the Associate Dean for Admissions for the Faculty of Science from 2011 till 2016

 

PhD Positions

Click here for current PhD opportunities in PHA. But feel free to email me to discuss projects outside these areas and alternative sources of funding.

 

Selected Publications

 

K. Buffet, I. Nierengarten, N. Galanos,E. Gillon, M. Holler,A. Imberty, S. E. Matthews, S. Vidal, S. P. Vincent,J.-F. Nierengarten

Pillar[5]arene-based glycoclusters: synthesis and multivalent binding to pathogenic bacterial lectins

Chem. Eur. J., 2016, 22, 2955-2963

 

A. M. Boukerb, A. Rousset, N. Galanos, J.-B. Méar, M. Thepaut, T. Grandjean, E. Gillon, S. Cecioni, C. Abderrahmen, K. Faure, D. Redelberger, E. Kipnis, R. Dessein, S. Havet, B. Drablade, S. E. Matthews, S. de Bentzmann, B. Guéry, B. Cournoyer, A. Imberty, S. Vidal

Anti-adhesive properties of glycoclusters against Pseudomonas aeruginosa lung infection

J. Med. Chem., 2014, 57, 10275-10289

 

Y. Brissonnet, C. Ortiz-Mellet, S. Morandat, D. Deniaud, S. E. Matthews,  S. Vidal, K. El Kirat S. G. Gouin

Topological effects and binding modes operating with multivalent iminosugar-based glycoclusters and glycosidases

J. Am. Chem. Soc. 2013, 135, 18427-18435

 

S. Cecioni, J.-P. Praly, S. E. Matthews M. Wimmerová, A. Imberty, S. Vidal

Rational design and synthesis of optimized glycoclusters for multivalent lectin-carbohydrate interactions: Influence of the linker arm.

Chem. Eur. J. 2012, 18, 6250-6263   

Administrative Posts

 

Chair of South East Asia Dialogue Group

Chair of Pharmacy Extenuating Circumstances Panel

School of Pharmacy Plaigiarism and Collusion officer

Member of School Teaching Executive

Member of School Examinations Board

Module coordinator: Drug Design and Mechanisms of Drug Action

Teaching Interests

I teach Medicinal Chemistry and Molecular pharmaceutics from Year 2 onwards.

Current teaching responsibilities include:

  • PHA5001Y Drug Design and Mechanism of Drug Action
  • PHA6004Y Evidence based care of Cardiovascular and Renal Disease
  • PHA6012Y Therapeutic Approaches to Gastrointestinal Diseases and Cancer
  • PHA7001B Neurology and Mental Health
  • PHA7003B Special Topics for Pharmacists
  • PHA7004Y Pharmaceutical Research Project

Key Research Interests

Research is focused on the interface between chemistry and biology and particularly on the use of supramolecular systems for drug and gene delivery and in novel antibacterial treatments. Current projects include:

  • Gene delivery through functionalised multicalixarenes
  • Cell imaging using fluorescently labelled macrocycles
  • Anti-adhesives as an approach to antibacterial treatment
  • Site-specific pro-drug systems for new anti-cancer agents
  • New antibiotics related to algae extracts
  • New cation and anion receptors based on calixarenes
  • Synthesis of new macrocyclic systems

 

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Keywords

  • Chemistry
  • Calixarenes
  • Cation Binding
  • Resorcinarenes
  • Anion Binding
  • Macrocycles
  • Antibacterials
  • Drug Delivery
  • Multivalency
  • Gene Delivery

Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or