Projects per year
Personal profile
Biography
Thomas Storr is a Lecturer in Organic Chemistry with research interests centred around the use of transition metal catalysts to develop new and sustainable organic synthetic methodologies. See the Storr Group Website for further details.
Thomas is originally from Darlington in the North East of England. He began studying Chemistry at the University of York, completing his MChem with a year in industry (F. Hoffmann-La Roche, Basel, CH) in 2006. Continuing at the University of York, Thomas obtained his PhD working under the supervision of Prof. Ian Fairlamb and Dr Christoph Baumann. He then pursued his interest in organic synthesis by taking up postdoctoral research posts with Prof. Bert Maes (Antwerp, BE), Prof. Michael Greaney (Manchester, UK) and Prof. Robert Stockman (Nottingham, UK). In 2017, Thomas started his current post at the University of East Anglia.
The Storr Group research interests lie first and foremost with development of novel synthetic methodology, with particular emphasis upon improving current processes with respect to applicability, sustainability and molecular/procedural economy. Current research is focused on the selective functionalisation of carbon-hydrogen bonds, utilising dual catalytic systems and the development of earth abundant metal-catalysed processes.
Selected Publications
Versatile C(sp²)-C(sp³) Ligand Couplings of Sulfoxides for the Enantioselective Synthesis of Diarylalkanes.
W. M. Dean, M. Šiaučiulis, T. E. Storr, W. Lewis, R. A. Stockman; Angew. Chem. Int. Ed., 2016, 55, 10013-10016.
DOI: 10.1002/anie.201602264
Facile Access to a Heterocyclic, sp³-Rich Chemical Scaffold via a Tandem Condensation/Intramolecular Nitrone–Alkene [3+2] Cycloaddition Strategy.
M. J. Rawling, T. E. Storr, W. A. Bawazir, S. J. Cully, W. Lewis, M. S. I. T. Makki, I. R. Strutt, G. Jones, D. Hamza and R. A. Stockman; Chem. Commun., 2015, 51, 12867-12870.
DOI: 10.1039/C5CC05070G
Palladium Catalyzed Arylation of Simple Arenes with Iodonium Salts.
T. E. Storr, M. F. Greaney; Org. Lett., 2013, 15, 1410–1413.
DOI: 10.1021/ol400412z
On the Appearance of Nitrite Anion in [PdX(OAc)L2] and [Pd(X)(C^N)L] Syntheses (X = OAc or NO2): Photocrystallographic Identification of Metastable Pd(η1-ONO)(C^N)PPh3.
S. E. Bajwa, T. E. Storr, L. E. Hatcher, T. J. Williams, C. G. Baumann, A. C. Whitwood, D. R. Allan, S. J. Teat, P. R. Raithby, I. J. S. Fairlamb; Chem. Sci., 2012, 3, 1656–1661.
DOI: 10.1039/C2SC01050J
Pd(0)/Cu(I)-Mediated Direct Arylation of 2′-Deoxyadenosines: Mechanistic Role of Cu(I) and Reactivity Comparisons with Related Purine Nucleosides.
T. E. Storr, C. G. Baumann, R. J. Thatcher, S. De Ornellas, A. C. Whitwood, I. J. S. Fairlamb; J. Org. Chem., 2009, 74, 5810–5821 (Featured Article).
DOI: 10.1021/jo9012282
Key Research Interests
Synthetic organic chemistry is a truly irreplaceable field of science, where the production of almost any molecular entity devised can be accomplished. Although the molecular construction ‘tool box’ is effective there remains inadequacies associated with specificity, selectivity and efficiency. To address this, metal-catalysis promises the removal of extraneous chemical transformations from multistep syntheses, allowing more concise overall processes. This ability to reduce the economic and time cost of complex molecular syntheses is highly favourable in light of the current need to accommodate for an increasingly sustainable chemical future. The groups research will investigate new ways in which molecules can be constructed delivering significant improvements over contemporary methods. This ability for chemists to discover and develop synthetic methods is based upon fundamental mechanistic understanding. With this in mind, the design synthesis and evaluation of new and effective homogeneous, heterogeneous and dual catalytic systems is a continuing goal for the Storr Research Group. To exemplify the applicability of the synthetic methodologies generated, the synthesis of pharmaceutically relevant molecules and natural products is achieved utilising these new tools.
Network
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Gas chromatography-mass-spectrometry and fluorescence facilities
Lettice, F., Fielden, J., Marin, M. J., Munoz-Herranz, M. P., Sachdeva, A., Storr, T., Waller, Z., Wildgoose, G. & Wright, J.
Engineering and Physical Sciences Research Council
1/10/18 → 31/03/20
Project: Research
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Research output
- 19 Article
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(−)-Brunneusine, a new phenolic compound with antibacterial properties in aqueous medium from the leaves of Agelanthus brunneus (Engl.) Tiegh (LORANTHACEAE)
Wieland Moifo Kuete, T., Ambassa, P., Luciane Moungang, M., Ngameni, B., Storr, T. E., Ngadjui Tchaleu, B. & Stephenson, G. R., Mar 2022, In: Zeitschrift für Naturforschung C. 77, 3-4, p. 157-165 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)5 Downloads (Pure) -
Synthesis of novel stilbene–coumarin derivatives and antifungal screening of monotes kerstingii-specialized metabolites against fusarium oxysporum
Fotso, G. W., Ngameni, B., Storr, T. E., Ngadjui, B. T., Mafu, S. & Stephenson, G. R., 25 Aug 2020, In: Antibiotics. 9, 9, p. 1-13 13 p., 537.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)22 Downloads (Pure) -
Trypanocidal and leishmanicidal activity of six limonoids
Steverding, D., Sidjui, L. S., Ferreira, É. R., Ngameni, B. N., Folefoc, G. N., Mahiou-Leddet, V., Ollivier, E., Stephenson, G. R., Storr, T. & Tyler, K., Jun 2020, In: Journal of Natural Medicines. 74, 3, p. 606–611 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)27 Downloads (Pure) -
Cross-Dehydrogenative-Coupling of Alkoxybenzenes with Toluenes: Copper(II) Halide Mediated Tandem Halo/Benzylation of Arenes
Storr, T. E., Teskey, C. J. & Greaney, M. F., 12 Dec 2016, In: Chemistry - A European Journal. 22, 50, p. 18169-18178 10 p.Research output: Contribution to journal › Article › peer-review
11 Citations (Scopus) -
Expedient synthesis of an atypical oxazolidinone compound library
Cully, S. J., Storr, T. E., Rawling, M. J., Abeysena, I. R., Hamza, D., Jones, G., Pearce, C. A., Quddus, A., Lewis, W. & Stockman, R. A., 1 Nov 2016, In: Bioorganic & Medicinal Chemistry. 24, 21, p. 5249-5257 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)10 Downloads (Pure)