• 2.44 Biology

Accepting PhD Students

PhD projects

https://www.uea.ac.uk/course/phd-doctorate/how-does-the-unusual-metabolism-of-cable-bacteria-impact-iron-and-sulfur-cycling-in-coastal-sediments-clarke-ubio23aries

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Personal profile

Administrative Posts

  • Biological Sciences Postgraduate Research Co-Director
  • Natural Sciences Exam Board Chair
  • Module organiser for 3rd Year BIO-6004A Microbial Biotechnology
  • Module organiser for 1st Year BIO-4007Y Physical and Analytical Methods in Biological Sciences

Career

  • Professor of Protein Biochemistry, University of East Anglia  (2021-present)
  • Lecturer, University of East Anglia (2011-2021) 
  • RCUK research Fellow, University of East Anglia (2006-2011)
  • Senior Research Associate, University of East Anglia (2003-2006)
  • Research Fellow, University of Michigan (2001-2003)
  • Ph.D. John Innes Centre, University of East Anglia (1998-2001)
  • M.Sc. Biomolecular Technology, University of Leicester (1997)
  • B.Sc. Biochemistry, University College London, University of London (1992-1995)


ResearcherID  

http://www.researcherid.com/rid/D-1837-2009  

External Activities

  • Ambassador of the Biochemical society (2022-)
  • Associate Editor of Scientific Reports
  • External Board member of 'Centre of Electromicrobiology', Aarhus Denmark

Key Research Interests

My interests lie in the characterisation of enzymes that contain metal cofactors, principally enzymes involved in bacterial respiration. These include soluble cytoplasmic and periplasmic proteins, integral membrane proteins as well as extracellular membrane associated proteins that interact with the environment. In collaboration with colleagues in the Centre for Molecular and Structural Biochemistry, my research combines a broad range of biological, biochemical and biophysical techniques to explore protein-protein interactions, electron transfer between cofactors and the mechanism of enzyme catalysis.

Video

Current Research Projects 

  • Extracellular electron transfer
  • Interactions between outer membrane cytochromes and mineral surfaces
  • Reverse electron transfer (bioelectrosynthesis)

 

Life in our Research Group

The actions of bacteria have a profound effect on the global environment, from the cycling of greenhouse gases to the availability of minerals and nutrients in the soil. We are interested in how these processes work on a molecular level through the action of enzymes expressed by the bacteria. In order to study these enzymes we employ a broad variety of techniques across the breadth of the science faculty; from spectroscopic methods such as Cyclic voltammetry in the Biophysical suite in Chemistry to the culturing of micro-organisms in the Wolfson Fermentation Suite in Biology. Our group is based in a well furnished laboratory on floor 2 of BIO, where we share laboratory space and equipment with Prof. Richardson, Prof. Hemmings, Dr Gates and Dr Swainsbury.


PhD Positions

Click here for current PhD opportunities in Biological Sciences. But feel free to email me to discuss projects outside these areas and alternative sources of funding.

Postdocs & Fellows

I am always happy to discuss possibilities for postdoctoral work and collaborations. Possible funding routes include applying for fellowships, e.g. EU Marie Curie fellowships, with me acting as sponsor, or grant applications with you as a named postdoc.

Teaching Interests

  • Microbial biotechnology (BIO-6004A) (Module organiser)
  • Molecular Enzymology in Biology and Medicine (BIO-6001A)
  • Biochemistry (BIO-5002A)
  • Microbiology (BIO-5015B)
  • Physical and Analytical Methods in the Biolmolecular Sciences (BIO-4007Y)
  • Skills for Biologists (BIO-4008Y)

Network

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or