Professional Qualifications and professional memberships

• MSc in Medical Statistics (University of Leicester)

• PhD in Economics (University of Nottingham)

• PGCHE in Higher Education (University of Nottingham)

• PGCert in Health Services Research (University of Nottingham)

• MSc in Health Economics (University of York)

• BA(Hons) Economics (University of Kent)

• Member of the UK Health Economics Study Group

• Member of the International Health Economics Association

Research interests

• Health economics

• Economic evaluation methodology and application

• Outcome measurement including non-monetary preference based methods

• Economics of Dermatology

• Economics of Falls prevention

• Economics of Rehabilitation 

Career summary

Tracey is a Professor in Health Economics at the University of Southampton. Tracey is a visiting Professor of Health Economics within Norwich Medical School at UEA, having been a Professor, Reader and Senior Lecturer in Health economics at UEA for over 15 years. Prior to this Tracey was a Lecturer in Health Economics within the Medical Faculty at the University of Nottingham, and an assistant economist at the Department of Health.

Awards 

• 2019 UEA Faculty of Medicine and Health Sciences Research Impact Prize

• Jan 2015 to Dec 2018 NIHR Career Development Fellowship 

• 2015 UEA Faculty of Medicine and Health Sciences Research Award 

• July 2011 - Best paper award – SWET trial results presented at British Association of Dermatologists’ Annual Conference

• July 2009 - The Society for Academic Primary Care Award for best submitted abstract: A randomised controlled trial assessing effects of weight loss and quadriceps strengthening exercises on pain and function in overweight people with knee pain.

• 9-11th September 2008 - ESRC Bursary for training to attend the Regression Methods for Health Economic Evaluation, University of York (£1,000)

• 13th June 2007 - The 2007 ISSLS Prize in Clinical Science, awarded at the 34th ISSLS Meeting in Hong Kong. “Steele N, Freeman B, Sach T, Hegarty J, Soegaard R. Cost-Effectiveness of Two Forms of Circumferential Lumbar Fusion: A Prospective, Randomised, Controlled Trial.” ($11,000)

• October – December 2005 - Honorary Lecturer at the University of Melbourne, Australia. Visit funded by a Universitas 21 Staff fellowship. Based in the Program Evaluation Unit. (£3,121)

• 2004 - Young Investigator award at the Tenth National Osteoporosis Society Conference, 28 November - 1 December 2004, in Harrogate. (£300)

• 1999 - Magellan award for exam performance, MSc in Health Economics 

Selected conference presentations

Why is it important to publish cost-ineffective findings from studies that are not clinically effective? A case study. Poster presentation at the iHEA congress 2021.

Can the Treatment Uncertainties Identified by the James Lind Alliance Priority Setting Partnerships be Used to Identify Research Questions for Which the Value of Gathering Further Evidence Can be Quantified?  Poster Presentation at 5th International Clincial Trials Methodology Conference 2019.  

The comparative performance of the CHU-9D and ADQoL amongt children aged 5 years or more with eczema: Evidence from the CLOTHES randomised controlled trial. Oral presentation at ISPOR 20th Annual European Conference, Glasgow, UK, 6th-8th November 2017.

What is the scope and quality of economic evidence available for atopic eczema? A systematic review. Poster presentation at ISPOR 20th Annual European Conference, Glasgow, UK, 6th-8th November 2017. (Poster Finalist award)

The importance of perspective when evaluating the Economic value of vocational rehabilitation. Poster presentation at ISPOR 20th Annual European Conference, Glasgow, UK, 6th-8th November 2017

Exploring the use of value of information methods to prioritise research to address the treatment uncertainties identified by the James Lind Alliance Priority Setting Partnerships. Sach T and McManus E. Poster presentation at ISPOR 18th Annual European Conference, Milan, Italy, 9-11th November 2015.

Resource use measurement in trial conducted in care homes: A study of level-of agreement between data collected from GP records and care home records. Sach T, Desborough J, Houghton J, Holland R. Poster presentation at ISPOR 18th Annual European Conference, Milan, Italy, 9-11th November 2015.

Could value of information methods be useful in prioritising research to address the treatment uncertainties identified by James Lind Alliance Priority setting partnerships? Sach T. Oral presentation at the REWARD / EQUATOR Conference: Increasing value and reducing waste in biomedical research, Edinburgh, UK 28-30 September 2015.

I am actively engaged in a number of economic evaluations alongside clinical trials. I am an experienced collaborator, leading the health economic aspects within numerous NIHR funded clinical trials. Open to new collaborations.

Current on-going projects include:

Cellulitis Optimal Antibiotic Treatment: COAT study. Francis N, Santer M, Thomas K, Levell N, Little P, Stuart B, Nuttall J, Read R, Sach T. NIHR HTA, 48 months, £1,476,575.

Developing and testing an online intervention to support self-management, improve outcomes and reduce antibiotic use in acne. Santer M, Muller I, Stuart B, Thomas K, Layton A, Little P, Yardley L, Francis N, Ridd M, Sach T. Langan S, Soulsby I, Patel M, Dove S, Griffiths G, Thompson A.  NIHR Programme Grants for Applied Research, £1,901,577.

 Best systemic treatments for adults with atopic eczema over the long term (BEACON): A randomised, assessor-blind trial comparing ciclosporin, methotrexate and dupilumab. Smith C, Pink A, Chalmers J, Emsley R, Williams H, Parmar M, Sach T, Reynolds N, Smith S, Murphy C, Cape A, Kelly J, Burton T, Dougans A, Kelly J, Proctor A. NIHR HTA Programme, 48 months, £1,899,852

A randomised controlled trial to determine whether skin barrier enhancement with emollients can prevent eczema in high risk children (BEEP). (Williams H, Chalmers J, Ridd M, Yang M, Leighton M, Sach T, Thornton J, Thomas K, Boyle R, cork M, Simpson E, Lawton S. Study funded by the NIHR Health Technology Assessment Programme). Trial website: https://www.nottingham.ac.uk/research/groups/cebd/projects/1eczema/beep-maintrial.aspx

Methotrexate versus Ciclosporin in the treatment of severe atopic eczema in children: An Economic Evaluation. Sach T, Flohr C, Wagner A, Jones A, Williamson P. NIHR RfPB, 32 months). Trial website: http://treat-trial.org.uk/

Supporting self-care for eczema in the community. Santer M, Thomas K, Little P, William H, Muller I, Yardley L, Chalmers J, Ridd M, Stuart B, Firkins L, Sach T, Lawton S, Roberts A, Wood W, Ratib S, Snell T. (NIHR Programme Grants for Applied Research, 5.5. years). Website: https://www.southampton.ac.uk/medicine/academic_units/projects/eco.page

RETurn to work After stroKE (RETAKE). Radford K, Bowen A, Farrin A, McKevitt C, Sach T, Walker M, O’Connor R, Watkins C. (NIHR HTA, 01/01/2017 for 54 months). Trial website: https://www.nottingham.ac.uk/research/groups/longtermconditions/vocational-rehabilitation/retake/index.aspx

Spironolactone for Adult Female Acne (SAFA): pragmatic multicentre double-blind randomised superiority trial to investigate the clinical and cost-effectiveness of spironolactone for moderate or severe persistent acne in women. Santer M, Griffiths G, Sach T, Ridd M, Francis N, Stuart B, Darvey A, Layton A, Snelling A, Thomas K, Muller I, August S, Thomas K, Little P. (NIHR HTA, 42 months). Trial website: https://www.southampton.ac.uk/safa/index.page

Selected publications

Logan PA, Horne JC, Gladman JRF, Gordon AL, Sach T, Clark A, Robinson K, Armstrong S, Stirling S, Leighton P, Darby J, Allen F, Irvine L, Wilson ECF, Fox C, Conroy S, Mountain G, McCartney K, Godfrey M, Sims E. Multifactorial falls prevention programme compared with usual care in UK care homes for older people: multicentre cluster randomised controlled trial with economic evaluation. BMJ. 2021 Dec 7;375:e066991. doi: 10.1136/bmj-2021-066991.

Renz S, Chinnery F, Stuart B, Day L, Muller I, Soulsby I, Nuttall J, Thomas K, Thomas KS, Sach T, Stanton L, Ridd MJ, Francis N, Little P, Eminton Z, Griffiths G, Layton AM, Santer M. Spironolactone for adult female acne (SAFA): protocol for a double-blind, placebo-controlled, phase III randomised study of spironolactone as systemic therapy for acne in adult women. BMJ Open. 2021 Aug 26;11(8):e053876. doi: 10.1136/bmjopen-2021-053876.

Muller I, Stuart B, Sach T, Hooper J, Wilczynska S, Steele M, Greenwell K, Sivyer K, Yardley L, Williams HC, Chalmers JR, Leighton P, Howells LM, Ridd MJ, Lawton S, Griffiths G, Nuttall J, Langan SM, Roberts A, Ahmed A, Kirk H, Becque T, Little P, Thomas KS, Santer M. Supporting self-care for eczema: protocol for two randomised controlled trials of ECO (Eczema Care Online) interventions for young people and parents/carers. BMJ Open. 2021 Feb 5;11(2):e045583. doi: 10.1136/bmjopen-2020-045583.

Thorn, J., Davies, C. F., Brookes, S., Noble, S., Dritsaki, M., Gray, E., Hughes, D., Mihaylova, B., Petrou, S., Ridyard, C., Sach, T., Wilson, E., Wordsworth, S. & Hollingworth, W. Content of Health Economics Analysis Plans (HEAPs) for trial-based economic evaluations: expert Delphi consensus survey. Value in Health (2021) 24(4): 539-547.

Chalmers JR, Haines RH, Bradshaw LE, Montgomery AA, Thomas KS, Brown SJ, Ridd MJ, Lawton S, Simpson EL, Cork MJ, Sach TH, Flohr C, Mitchell EJ, Swinden R, Tarr S, Davies-Jones S, Jay N, Kelleher MM, Perkin MR, Boyle RJ, Williams HC; BEEP study team. Daily emollient during infancy for prevention of eczema: the BEEP randomised controlled trial. Lancet. 2020 Mar 21;395(10228):962-972. doi: 10.1016/S0140-6736(19)32984-8. Epub 2020 Feb 19.

Radford KA, Craven K, McLellan V, Sach TH, Brindle R, Holloway I, Hartley S, Bowen A, O'Connor R, Stevens J, Philips J, Walker M, Holmes J, McKevitt C, Murray J, Watkins C, Powers K, Shone A, Farrin A.

An individually randomised controlled multi-centre pragmatic trial with embedded economic and process evaluations of early vocational rehabilitation compared with usual care for stroke survivors: study protocol for the RETurn to work After stroKE (RETAKE) trial. Trials. 2020 Dec 9;21(1):1010. doi: 10.1186/s13063-020-04883-1.

Sach TH, Thomas KS, Batchelor JM, Akram P, Chalmers JR, Haines RH, Meakin GD, Duley L, Ravenscroft JC, Rogers A, Santer M, Tan W, White J, Whitton ME, Williams HC, Cheung ST, Hamad H, Wright A, Ingram JR, Levell N, Goulding JMR, Makrygeorgou A, Bewley A, Ogboli M, Stainforth J, Ferguson A, Laguda B, Wahie S, Ellis R, Azad J, Rajasekaran A, Eleftheriadou V, Montgomery AA; UK Dermatology Clinical Trials Network’s HI-LIGHT Vitiligo Trial Team. An economic evaluation of the randomised controlled trial of topical corticosteroid and home-based narrowband UVB for active and limited vitiligo (The HI-Light Trial). Br J Dermatol. 2020 Sep 12. doi: 10.1111/bjd.19554.

Thomas KS, Batchelor JM, Akram P, Chalmers JR, Haines RH, Meakin GD, Duley L, Ravenscroft JC, Rogers A, Sach TH, Santer M, Tan W, White J, Whitton ME, Williams HC, Cheung ST, Hamad H, Wright A, Ingram JR, Levell NJ, Goulding JMR, Makrygeorgou A, Bewley A, Ogboli M, Stainforth J, Ferguson A, Laguda B, Wahie S, Ellis R, Azad J, Rajasekaran A, Eleftheriadou V, Montgomery AA; UK Dermatology Clinical Trials Network’s HI-LIGHT Vitiligo Trial Team. Randomised controlled trial of topical corticosteroid and home-based narrowband UVB for active and limited vitiligo - results of the HI-Light Vitiligo trial. Br J Dermatol. 2020 Oct 2.

Batchelor JM, Thomas KS, Akram P, Azad J, Bewley A, Chalmers JR, Cheung ST, Duley L, Eleftheriadou V, Ellis R, Ferguson A, Goulding JM, Haines RH, Hamad H, Ingram JR, Laguda B, Leighton P, Levell N, Makrygeorgou A, Meakin GD, Millington A, Ogboli M, Rajasekaran A, Ravenscroft JC, Rogers A, Sach TH, Santer M, Stainforth J, Tan W, Wahie S, White J, Whitton ME, Williams HC, Wright A, Montgomery AA. Home-based narrowband UVB, topical corticosteroid or combination for children and adults with vitiligo: HI-Light Vitiligo three-arm RCT. Health Technol Assess. 2020 Nov;24(64):1-128. doi: 10.3310/hta24640.

• PGR lead for the Health Economics Group
• Module lead for the dissertation module on the MSc in Health Economics
• Module lead for the Health Economics module on the MSc in Health Economics
• Personal Advisor for students on the MSc in Health Economics and MBBS
• Deputy chair for the FMH PGT extenuating circumstances panel

Module lead for the Dissertation module of the MSc in Health Economics 

Module lead for the MED-M07D Health Economics module of the MSc in Health Economics

Supervision of postgraduate research degree students in areas to do with health economics and economic evaluation.