• 2.37 Medical School

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Personal profile

Academic Background

 

Professional Qualifications and professional memberships

  • MSc in Medical Statistics (University of Leicester)

  • PhD in Economics (University of Nottingham)

  • PGCHE in Higher Education (University of Nottingham)

  • PGCert in Health Services Research (University of Nottingham)

  • MSc in Health Economics (University of York)

  • BA(Hons) Economics (University of Kent)

  • Member of the UK Health Economics Study Group

  • Member of the International Health Economics Association

 

Research interests

  • Health economics

  • Economic evaluation methodology and application

  • Outcome measurement including non-monetary preference based methods

  • Economics of Dermatology

  • Economics of Falls prevention

  • Economics of Rehabilitation 

 

Career summary

Tracey is a Professor of Health Economics within Norwich Medical School at UEA, having been Reader and Senior Lecturer in Health economics within the same School. Prior to this Tracey has been a Senior Lecturer in Health Economics within the Pharmacy School at UEA, Lecturer in Health Economics within the Medical Faculty at the University of Nottingham, and an assistant economist at the Department of Health.

 

Awards 

  • 2019 UEA Faculty of Medicine and Health Sciences Research Impact Prize
  • Jan 2015 to Dec 2018 NIHR Career Development Fellowship 

  • 2015 UEA Faculty of Medicine and Health Sciences Research Award 
  • July 2011 - Best paper award – SWET trial results presented at British Association of Dermatologists’ Annual Conference

  • July 2009 - The Society for Academic Primary Care Award for best submitted abstract: A randomised controlled trial assessing effects of weight loss and quadriceps strengthening exercises on pain and function in overweight people with knee pain.

  • 9-11th September 2008 - ESRC Bursary for training to attend the Regression Methods for Health Economic Evaluation, University of York (£1,000)

  • 13th June 2007 - The 2007 ISSLS Prize in Clinical Science, awarded at the 34th ISSLS Meeting in Hong Kong. “Steele N, Freeman B, Sach T, Hegarty J, Soegaard R. Cost-Effectiveness of Two Forms of Circumferential Lumbar Fusion: A Prospective, Randomised, Controlled Trial.” ($11,000)

  • October – December 2005 - Honorary Lecturer at the University of Melbourne, Australia. Visit funded by a Universitas 21 Staff fellowship. Based in the Program Evaluation Unit. (£3,121)

  • 2004 - Young Investigator award at the Tenth National Osteoporosis Society Conference, 28 November - 1 December 2004, in Harrogate. (£300)

  • 1999 - Magellan award for exam performance, MSc in Health Economics 

 

Selected conference presentations

 

Why is it important to publish cost-ineffective findings from studies that are not clinically effective? A case study. Poster presentation at the iHEA congress 2021.

 

Can the Treatment Uncertainties Identified by the James Lind Alliance Priority Setting Partnerships be Used to Identify Research Questions for Which the Value of Gathering Further Evidence Can be Quantified?  Poster Presentation at 5th International Clincial Trials Methodology Conference 2019.  

 

The comparative performance of the CHU-9D and ADQoL amongt children aged 5 years or more with eczema: Evidence from the CLOTHES randomised controlled trial. Oral presentation at ISPOR 20th Annual European Conference, Glasgow, UK, 6th-8th November 2017.

 

What is the scope and quality of economic evidence available for atopic eczema? A systematic review. Poster presentation at ISPOR 20th Annual European Conference, Glasgow, UK, 6th-8th November 2017. (Poster Finalist award)

 

The importance of perspective when evaluating the Economic value of vocational rehabilitation. Poster presentation at ISPOR 20th Annual European Conference, Glasgow, UK, 6th-8th November 2017

 

Exploring the use of value of information methods to prioritise research to address the treatment uncertainties identified by the James Lind Alliance Priority Setting Partnerships. Sach T and McManus E. Poster presentation at ISPOR 18th Annual European Conference, Milan, Italy, 9-11th November 2015.

 

Resource use measurement in trial conducted in care homes: A study of level-of agreement between data collected from GP records and care home records. Sach T, Desborough J, Houghton J, Holland R. Poster presentation at ISPOR 18th Annual European Conference, Milan, Italy, 9-11th November 2015.

 

Could value of information methods be useful in prioritising research to address the treatment uncertainties identified by James Lind Alliance Priority setting partnerships? Sach T. Oral presentation at the REWARD / EQUATOR Conference: Increasing value and reducing waste in biomedical research, Edinburgh, UK 28-30 September 2015.

 

 

External Activities

  • Chair of the NIHR Research for Patient Benefit East of Engliand Research Advisory Committee (2020-)
  • Member of the Marie Curie Research funding Committee (2019-)
  • Member of the NIHR HTA Commissioning Board (2017-2019)
  • Member of the NIHR HTA General board (2016-2017)
  • Core Member of the NIHR HTA Themed calls board (2013-2016)
  • NIHR Research methods fellowships and internship funding panel (2014, 2015, 2016, 2017, 2018)
  • Independent member of the trial Steering committees for HomeHealth, INSPIRE and WAX funded by the NIHR.
  • Chair of the Scientific and organising committee for the Summer 2019 HESG conference held at UEA, 3rd-5th July.
  • Programme chair for the 2019 (Basel) and 2021 (South Africa) International Health Economics Association conference.
  • Member of the Expert Review Panel for NIHR Research Methods Economics of Health: Funding for Masters Studentships in the Economics of Health  – Round 4 (2017)
  • NIHR Systematic Reviews Fellowships funding panel (2015)
  • Member of the high-level expert panel of the Research Agenda for Health Economic Evaluation (RAHEE) project conducted by the World Health Organisation representation to the European Union (3rd-5th Feb 2015) (http://www.euro.who.int/en/about-us/organization/office-locations/who-representation-to-the-european-union,-brussels,-belgium/research-agenda-for-health-economic-evaluation-rahee-project)
  • Participated in the Harmonising Outcome Measures for Eczema (HOME) IV meeting in Malmo, Sweden (April 2015)(http://www.nottingham.ac.uk/homeforeczema/index.aspx)
  • Member of the Public Health Interventions Advisory Committee for NICE (2007-2012)
  • Honorary Lecturer in Health Economics, University of Nottingham, UK (2007-)
  • Senior Fellow, The Institute of Mental Health, Nottingham (2006-)
  • Member of the ESRC college of expert reviewers (2010-)
  • Grant and report reviewer for the UK Health Technology Assessment programme
  • Referee for the various journals including the British Medical Journal, European Journal of Health Economics, Health Economics, International Journal of Obesity, Medical Decision Making, Pharmacoeeconomics, Social Science and Medicine, Quality of Life Research, and Value in Health.

Key Research Interests and Expertise

I am actively engaged in a number of economic evaluations alongside clinical trials. I am an experienced collaborator, leading the health economic aspects within numerous NIHR funded clinical trials. Open to new collaborations.

 

Current on-going projects include:

 

Smith C, Pink A, Chalmers J, Emsley R, Williams H, Parmar M, Sach T, Reynolds N, Smith S, Murphy C, Cape A, Kelly J, Burton T, Dougans A, Kelly J, Proctor A. Best systemic treatments for adults with atopic eczema over the long term (BEACON): A randomised, assessor-blind trial comparing ciclosporin, methotrexate and dupilumab. NIHR HTA Programme, 48 months, £1,899,852

 

 

A randomised controlled trial to determine whether skin barrier enhancement with emollients can prevent eczema in high risk children (BEEP). (Williams H, Chalmers J, Ridd M, Yang M, Leighton M, Sach T, Thornton J, Thomas K, Boyle R, cork M, Simpson E, Lawton S. Study funded by the NIHR Health Technology Assessment Programme). Trial website: https://www.nottingham.ac.uk/research/groups/cebd/projects/1eczema/beep-maintrial.aspx


 

Methotrexate versus Ciclosporin in the treatment of severe atopic eczema in children: An Economic Evaluation. Sach T, Flohr C, Wagner A, Jones A, Williamson P. NIHR RfPB, 32 months). Trial website: http://treat-trial.org.uk/

 

Supporting self-care for eczema in the community. Santer M, Thomas K, Little P, William H, Muller I, Yardley L, Chalmers J, Ridd M, Stuart B, Firkins L, Sach T, Lawton S, Roberts A, Wood W, Ratib S, Snell T. (NIHR Programme Grants for Applied Research, 5.5. years). Website: https://www.southampton.ac.uk/medicine/academic_units/projects/eco.page

 

RETurn to work After stroKE (RETAKE). Radford K, Bowen A, Farrin A, McKevitt C, Sach T, Walker M, O’Connor R, Watkins C. (NIHR HTA, 01/01/2017 for 54 months). Trial website: https://www.nottingham.ac.uk/research/groups/longtermconditions/vocational-rehabilitation/retake/index.aspx

 

Spironolactone for Adult Female Acne (SAFA): pragmatic multicentre double-blind randomised superiority trial to investigate the clinical and cost-effectiveness of spironolactone for moderate or severe persistent acne in women. Santer M, Griffiths G, Sach T, Ridd M, Francis N, Stuart B, Darvey A, Layton A, Snelling A, Thomas K, Muller I, August S, Thomas K, Little P. (NIHR HTA, 42 months). Trial website: https://www.southampton.ac.uk/safa/index.page

 

 

Selected publications

  • Sach TH, McManus E, Levell NJ. Understanding economic evidence for the prevention and treatment of atopic eczema. Br J Dermatol. 2019 Oct;181(4):707-716.

  • McManus E, Turner D, Sach T. Can you repeat that? Exploring the Definition of a Successful Model Replication in Health Economics. Pharmacoeconomics (In Press).
  • McManus E, Turner D, Gray E, Khawar H, Okoli T, Sach T. Barriers and Facilitators to Model Replication Within Health Economics. Value Health. 2019 Sep;22(9):1018-1025.  
  • McManus E, Sach TH, Levell NJ. An introduction to the methods of
    decision-analytic modelling used in economic evaluations for Dermatologists. J Eur Acad Dermatol Venereol. 2019 May 25. doi: 10.1111/jdv.15713. [Epub ahead of print] Review. 
  • Mohindru B, Turner D, Sach T, Bilton D, Carr S, Archangelidi O, Bhadhuri A, Whitty JA. Health State Utility Data in Cystic Fibrosis: A Systematic Review. Pharmacoecon Open. 2019 May 3. doi: 10.1007/s41669-019-0144-1. [Epub ahead of print] Review. 
  • Crossman-Barnes CJ, Sach T, Wilson A, Barton G. Estimating loss in quality of  life associated with asthma-related crisis events (ESQUARE): a cohort, observational study. Health Qual Life Outcomes. 2019 Apr 11;17(1):58. 
  • Ban L, Langan SM, Abuabara K, Thomas KS, Abdul Sultan A, Sach T, McManus E, Santer M, Ratib S. Incidence and sociodemographic characteristics of eczema diagnosis in children: A cohort study. J Allergy Clin Immunol. 2018 Jan 31. pii: S0091-6749(18)30128-3. doi: 10.1016/j.jaci.2017.12.99
  • Sach T. Safety gains don't translate into reduced costs or increased QALYs for doxycycline compared with prednisolone for patients with bullous pemphigoid. Br J Dermatol. 2018 Feb;178(2):320-321. doi: 10.1111/bjd.16226

  

 

 

Key Responsibilities

  • PGR lead for the Health Economics Group
  • Module lead for the dissertation module on the MSc in Health Economics
  • Module lead for the Health Economics module on the MSc in Health Economics
  • Personal Advisor for students on the MSc in Health Economics and MBBS
  • Deputy chair for the FMH PGT extenuating circumstances panel

 

 

Teaching Interests

Module lead for the Dissertation module of the MSc in Health Economics 

Module lead for the MED-M07D Health Economics module of the MSc in Health Economics

Supervision of postgraduate research degree students in areas to do with health economics and economic evaluation. 

Network

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