Yaroslav Khimyak

Professor

  • 0.24 Chemistry

Accepting PhD Students

PhD projects

NRP/DTP studentship on Plant Cell Wall Hydrogels NRP?DTP studentship on Understanding of Lipid Digestion using NMR

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Personal profile

Biography

Click here for current PhD opportunities in PHA. But feel free to email me to discuss projects outside these areas and alternative sources of funding.

Yaroslav Khimyak has moved to a Chair in solid-state NMR spectroscopy in the School of Pharmacy in UEA in September 2011. Until then he was a Senior Lecturer at the Department of Chemistry in the University of Liverpool where he was appointed as a Lecturer in 2002. Yaroslav graduated from Ivan Franko Lviv State University in the Ukraine with an M.Sc. in Chemistry (1994), obtained an M. Phil. (1997) and a Ph. D. (2000) from the University of Cambridge and held a position of Oppenheimer Research Fellow at the Department of Chemistry in the University of Cambridge (1999 – 2002).

Research in YK’s group focuses on the understanding of structure and dynamics of materials with limited long range ordering using advanced NMR. The materials of interest include pharmaceutical solids (Mol. Pharm, 2016, 1012; 2015, 2981), polymers Angew. Chem. Int. Ed. 2011, 1072; 2007, 8574) and porous materials (Angew. Chem. Int. Ed., 2016, 8904; Science, 2010, 1053; J. Am. Chem. Soc., 2012, 20466; Nature Mater., 2014, 343; EP/J008834/1, EP/F057865/1). We have developed an NMR based methods for soft matter and heterogeneous materials where the understanding of intermolecular interactions is a considerable challenge and a complex approach based on the application of different methodologies is required (Chem. Eur. J., 2017, 8014; Soft Matter, 2016, 4034). The recent award of the EPSRC/Innovate UK grant “New Enzymatically Produced Interpenetrating Starch-Cellulose Gels” (EP/N033337/1, £2.8 M across UEA, JIC and Universities of Bristol and Bath) aims to develop an advanced NMR toolkit for soft materials.

Yaroslav Khimyak is the Head of the NMR steering group in NRP, a member of the Core Team of EPSRC Directed Assembly network, a member of RSC NMR DG committee and a member of Materials Focus group in the Academy of Pharmaceutical Sciences and a Consultant in NMR Crystallography Commission of the International Union of Crystallography.

Selected publications

An Adaptable Peptide-Based Porous Material
J. Rabone, Y. F. Yue, S. Y. Chong, K. C. Stylianou, J. Bacsa, D. Bradshaw, G. R. Darling, N. G. Berry, Y. Z. Khimyak, A. Y. Ganin, P. Wiper, J. B. Claridge, and M. J. Rosseinsky.
Science, 2010, 329, 1053-1057.
DOI:10.1126/science.119067

Effect of encapsulating a pseudo-decapeptide containing arginine on PLGA: a solid-state NMR study
J. B. Guilbaud, B. C. Clark, E. Meehan, L. Hughes, A. Saiani and Y. Z. Khimyak.
Journal of Pharmaceutical Sciences, 2010, 99, 2697-2710.
DOI: 10.1002/jps.22060

Amorphous Drug-PVP Dispersions: Application of Theoretical, Thermal and Spectroscopic Analytical Techniques to the Study of a Molecule with Intermolecular Bonds in Both the Crystalline and Pure Amorphous State
M. Tobyn, J. Brown, A. B. Dennis, M. Fakes, Q. Gao, J. Gamble, Y. Z. Khimyak, G. McGeorge, C. Patel, W. Sinclair, P. Timmins and S. Yin
Journal of Pharmaceutical Sciences, 2009, 98, 3456-3468.
DOI: 10.1002/jps.21738

Periodic mesoporous organosilicas with domain functionality: Synthesis and advanced characterization
J. T. A. Jones, C. D. Wood, C. Dickinson and Y. Z. Khimyak
Chemistry of Materials, 2008, 20, 3385-3397.
DOI: 10.1021/cm7036124

Specialisms

Nuclear magnetic resonance and related methods for characterisation of advanced materials including pharmaceuticals; materials for drug delivery - design and advanced characterisation; soft solids and porous materials - molecular level structure and dynamics.

Administrative Posts

Head of Pharmaceutical Materials and Drug Delivery Section

PGR Opportunities

NRP/DTP Studentship on Plant Cell Wall Hydrogels

PGR Opportunities

NRP/DTP Studentship on UNderstanding Lipid Digestion using NMR

Network

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or