Projects per year
Personal profile
Biography
Click here for current PhD opportunities in PHA. But feel free to email me to discuss projects outside these areas and alternative sources of funding.
Yaroslav Khimyak has moved to a Chair in solid-state NMR spectroscopy in the School of Pharmacy in UEA in September 2011. Until then he was a Senior Lecturer at the Department of Chemistry in the University of Liverpool where he was appointed as a Lecturer in 2002. Yaroslav graduated from Ivan Franko Lviv State University in the Ukraine with an M.Sc. in Chemistry (1994), obtained an M. Phil. (1997) and a Ph. D. (2000) from the University of Cambridge and held a position of Oppenheimer Research Fellow at the Department of Chemistry in the University of Cambridge (1999 – 2002).
Research in YK’s group focuses on the understanding of structure and dynamics of materials with limited long range ordering using advanced NMR. The materials of interest include pharmaceutical solids (Mol. Pharm, 2016, 1012; 2015, 2981), polymers Angew. Chem. Int. Ed. 2011, 1072; 2007, 8574) and porous materials (Angew. Chem. Int. Ed., 2016, 8904; Science, 2010, 1053; J. Am. Chem. Soc., 2012, 20466; Nature Mater., 2014, 343; EP/J008834/1, EP/F057865/1). We have developed an NMR based methods for soft matter and heterogeneous materials where the understanding of intermolecular interactions is a considerable challenge and a complex approach based on the application of different methodologies is required (Chem. Eur. J., 2017, 8014; Soft Matter, 2016, 4034).
Yaroslav Khimyak is the Head of the NMR steering group in NRP, a member of Materials Focus group in the Academy of Pharmaceutical Sciences and a Member of NMR Crystallography Commission of the International Union of Crystallography.
Yaroslav Khimyak was Unit of Assessment 3 (Allied Health Profession, Dentistry, Nursing and Pharmacy) coordinator for REF 2021 return from UEA and is Director of Reseach in PHA.
Areas of Expertise
Nuclear magnetic resonance and related methods for characterisation of advanced materials including pharmaceuticals; materials for drug delivery - design and advanced characterisation; soft solids and porous materials - molecular level structure and dynamics.
Administrative Posts
Head of Pharmaceutical Materials and Drug Delivery Section
Collaborations and top research areas from the last five years
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Addressing Interdisciplinary challenges through Raman Microscopy - a new facility for UEA
Lettice, F., Alexander, M., Askounis, A., Baker, A., Cammidge, A., Chao, Y., Fabian, L., Fielden, J., Hernaez, M., Hui, O., Kaplani, E., Khimyak, Y., Liss, P., Lord, R., Marin, M. J., Mayes, A., Melendi-Espina, S., Nolte, S., Romanov, A., Saeed, A., Sobolewski, A., Tolhurst, T. & Wright, J.
Engineering and Physical Sciences Research Council
6/11/20 → 31/08/22
Project: Research
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Enhanced single-crystal X-ray diffraction facilities
Bochmann, M., Fabian, L., Fielden, J., Khimyak, Y. & Wright, J.
Engineering and Physical Sciences Research Council
15/11/18 → 14/11/21
Project: Research
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Elucidation of biopolymer dissolution and gelation using NMR-imaging techniques.
Royal Commission for the Exhibition of 1851
1/10/17 → 31/12/20
Project: Fellowship
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Multi-phasic NMR analysis of composite nanocellulose hydrogels as plant cell wall mimics.
1/02/17 → 30/04/18
Project: Research
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Supramolecular amino acid based hydrogels: probing the contribution of additive molecules using NMR spectroscopy
Ramalhete, S., Nartowski, K., Sarathchandra, N., Foster, J., Round, A., Angulo, J., Lloyd, G. & Khimyak, Y., 12 Jun 2017, In: Chemistry - A European Journal. 23, 33, p. 8014–8024Research output: Contribution to journal › Article › peer-review
Open AccessFile42 Citations (Scopus)24 Downloads (Pure) -
19F NMR spectroscopy as a highly sensitive method for the direct monitoring of confined crystallization within nanoporous materials
Nartowski, K., Malhotra, D., Hawarden, L., Sibik, J., Iuga, D., Zeitler, J. A., Fabian, L. & Khimyak, Y., 25 Jul 2016, In: Angewandte Chemie International Edition. 128, 31, p. 9050-9054 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile29 Citations (Scopus)22 Downloads (Pure) -
Substituent interference on supramolecular assembly in urea gelators: synthesis, structure prediction and NMR
Piana, F., Case, D. H., Campos E Menezes Jorge Ramalhete, S., Pileio, G., Facciotti, M., Day, G. M., Khimyak, Y., Angulo, J., Brown, R. C. D. & Gale, P. A., 7 May 2016, In: Soft Matter. 12, 17, p. 4034-4043 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile28 Citations (Scopus)12 Downloads (Pure) -
Tuning the spontaneous formation kinetics of caffeine:malonic acid co-crystals
Nartowski, K., Khimyak, Y. & Berry, D., 21 Apr 2016, In: CrystEngComm. 18, 15, p. 2617-2620 4 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Citations (Scopus)14 Downloads (Pure) -
Structural properties, order-disorder phenomena and phase stability of orotic acid crystal forms
Braun, D., Nartowski, K., Khimyak, Y., Morris, K., Byrn, S. & Griesser, U., 7 Mar 2016, In: Molecular Pharmaceutics. 13, 3, p. 1012-1029 18 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile27 Citations (Scopus)11 Downloads (Pure)
Datasets
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Chemoenzymatic synthesis of fluorinated cellodextrins identifies a new allomorph for cellulose‐like materials
Muñoz-García, J. C. (Creator), de Andrade, P. (Contributor), Pergolizzi, G. (Contributor), Gabrielli, V. (Contributor), Nepogodiev, S. (Contributor), Iuga, D. (Contributor), Fabian, L. (Contributor), Nigmatullin, R. (Contributor), Johns, M. A. (Contributor), Harniman, R. (Contributor), Eichhorn, S. J. (Contributor), Angulo, J. (Contributor), Khimyak, Y. (Contributor) & Field, R. A. (Contributor), Wiley, 30 Sep 2020
Dataset
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Data for Rapid determination of the acidity, alkalinity and carboxyl content of aqueous samples by 1H NMR with minimal sample quantity
Wallace, M. (Creator), Lam, K. (Creator), Kuraite, A. (Creator) & Khimyak, Y. (Creator), American Chemical Society, 9 Sep 2020
DOI: 10.1021/acs.analchem.0c02594
Dataset
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Data for: Surfactant controlled zwitterionic cellulose nanofibril dispersions
Munoz Garcia, J. (Creator), Khimyak, Y. (Creator), Gabrielli, V. (Creator) & Angulo, J. (Creator), University of East Anglia, 7 Aug 2018
DOI: 10.1039/C8SM00752G
Dataset
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Data for: Understanding heat driven gelation of anionic cellulose nanofibrils: Combining saturation transfer difference (STD) NMR, small angle X-ray scattering (SAXS) and rheology
Calabrese, V. (Creator), Munoz Garcia, J. (Creator), Schmitt, J. (Creator), da Silva, M. A. (Creator), Scott, J. L. (Creator), Angulo, J. (Creator), Khimyak, Y. (Creator) & Edler, K. J. (Creator), University of East Anglia, 2018
DOI: 10.15125/BATH-00476
Dataset
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Nanocrystallization of Rare Tolbutamide Form V in Mesoporous MCM-41 Silica
Khimyak, Y. (Creator), University of East Anglia, 3 Oct 2019
Dataset