A new pathway for iron-sulphur cluster repair

Research output

Research output per year 2016 2017 2019 2022

• 8 Article

Research output per year

Research output per year

Search results

• 2022

  The di-iron protein YtfE is a nitric oxide-generating nitrite reductase involved in management of nitrosative stress

  Crack, J. C., Balasiny, B. K., Bennett, S. P., Rolfe, M. D., Froes, A., MacMillan, F., Green, J., Cole, J. A. & Le Brun, N. E., 27 Apr 2022, In: Journal of the American Chemical Society. 144, 16, p. 7129–7145 17 p.

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  8 Citations (Scopus)

  10 Downloads (Pure)
• 2019

  Crystal structure of the transcription regulator RsrR reveals a [2Fe-2S] cluster coordinated by Cys, Glu and His residues

  Volbeda, A., Pellicer Martinez, M. T., Crack, J. C., Amara, P., Gigarel, O., Munnoch, J. T., Hutchings, M. I., Darnault, C., Le Brun, N. E. & Fontecilla-Camps, J. C., 13 Feb 2019, In: Journal of the American Chemical Society. 141, 6, p. 2367–2375 9 p.

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  21 Citations (Scopus)

  17 Downloads (Pure)

• Mass spectrometric identification of [4Fe-4S](NO)_x intermediates of nitric oxide sensing by regulatory iron-sulfur cluster proteins

  Crack, J. C. & Le Brun, N., 7 Mar 2019, In: Chemistry - A European Journal. 25, 14, p. 3675-3684 10 p.

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  25 Citations (Scopus)

  10 Downloads (Pure)
• 2017

  Cmr is a redox-responsive regulator of DosR that contributes to M. tuberculosis virulence

  Smith, L. J., Bochkareva, A., Rolfe, M. D., Hunt, D. M., Kahramanoglou, C., Braun, Y., Rodgers, A., Blockley, A., Coade, S., Lougheed, K. EA., Hafneh, N. A., Glenn, S. M., Crack, J. C., Le Brun, N. E., Saldanha, J. W., Macarov, V., Nobeli, I., Arnvig, K., Mukamolova, G. V., Buxton, R. S., & 1 othersGreen, J., 20 Jun 2017, In: Nucleic Acids Research. 45, 11, p. 6600-6612 13 p.

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  20 Citations (Scopus)

  62 Downloads (Pure)

• Mass spectrometric identification of intermediates in the O2-driven [4Fe-4S] to [2Fe-2S] cluster conversion in FNR

  Crack, J. C., Thomson, A. J. & Le Brun, N. E., 18 Apr 2017, In: Proceedings of the National Academy of Sciences of the United States of America (PNAS). 114, 6, p. E3215–E3223 9 p.

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  43 Citations (Scopus)

  22 Downloads (Pure)

• Sensing iron availability via the fragile [4Fe-4S] cluster of the bacterial transcriptional repressor RirA

  Pellicer Martinez, M., Bermejo Martinez, A., Crack, J., Holmes, J. D., Svistunenko, D., Johnston, A., Cheesman, M., Todd, J. & Le Brun, N., 2017, In: Chemical Science. 8, p. 8451-8463 13 p.

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  27 Citations (Scopus)

  19 Downloads (Pure)

• Structure of a Wbl protein and implications for NO sensing by M. tuberculosis

  Kudhair, B. K., Hounslow, A. M., Rolfe, M. D., Crack, J. C., Hunt, D. M., Buxton, R. S., Smith, L. J., Le Brun, N. E., Williamson, M. P. & Green, J., 22 Dec 2017, In: Nature Communications. 8, 2280.

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  37 Citations (Scopus)

  24 Downloads (Pure)
• 2016

  Nitrosylation of nitric-oxide-sensing regulatory proteins containing [4Fe-4S] clusters gives rise to multiple iron-nitrosyl complexes

  Serrano, P. N., Wang, H., Crack, J. C., Prior, C., Hutchings, M. I., Thomson, A. J., Kamali, S., Yoda, Y., Zhao, J., Hu, M. Y., Alp, E. E., Oganesyan, V. S., Le Brun, N. E. & Cramer, S. P., 14 Nov 2016, In: Angewandte Chemie-International Edition. 55, 47, p. 14575–14579 5 p.

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  29 Citations (Scopus)

  18 Downloads (Pure)