A structural context for the mechanism of Uncoupling protein 1

Crichton, Paul (Principal Investigator)

Status	Finished
Effective start/end date	1/05/19 → 31/07/23

Funding

Biotechnology and Biological Sciences Research Council: £438,589.36

2 Article
1 Review article

Structural mechanisms of mitochondrial uncoupling protein 1 regulation in thermogenesis
Jones, S. A., Ruprecht, J. J., Crichton, P. G. & Kunji, E. R. S., Jun 2024, In: Trends in Biochemical Sciences. 49, 6, p. 506-519 14 p.
Research output: Contribution to journal › Review article › peer-review

Open Access
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6 Citations (Scopus)

5 Downloads (Pure)
Structural basis of purine nucleotide inhibition of human uncoupling protein 1
Jones, S. A., Gogoi, P., Ruprecht, J. J., King, M. S., Lee, Y., Zögg, T., Pardon, E., Chand, D., Steimle, S., Copeman, D. M., Cotrim, C. A., Steyaert, J., Crichton, P. G., Moiseenkova-Bell, V. & Kunji, E. R. S., 2 Jun 2023, In: Science Advances. 9, 22, eadh4251.
Research output: Contribution to journal › Article › peer-review

Open Access
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23 Citations (Scopus)

14 Downloads (Pure)
Activating ligands of Uncoupling protein 1 identified by rapid membrane protein thermostability shift analysis
Cavalieri, R., Hazebroek, M. K., Cotrim, C. A., Lee, Y., Kunji, E. R. S., Jastroch, M., Keipert, S. & Crichton, P. G., Aug 2022, In: Molecular Metabolism . 62, 101526.
Research output: Contribution to journal › Article › peer-review

Open Access
File

10 Citations (Scopus)

13 Downloads (Pure)