Getting to the root of ageing: somatic decay as a cost of germline maintenance

Maklakov, Alexei (Principal Investigator)

Status	Finished
Effective start/end date	1/09/17 → 28/02/23

Funding

European Research Council: £1,398,601.00

4 Article
1 Letter

Multigenerational downregulation of insulin/IGF-1 signaling in adulthood improves lineage survival, reproduction, and fitness in Caenorhabditis elegans supporting the developmental theory of ageing
Duxbury, E. M. L., Carlsson, H., Sales, K., Sultanova, Z., Immler, S., Chapman, T. & Maklakov, A. A., Dec 2022, In: Evolution. 76, 12, p. 2829-2845 17 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File

3 Citations (Scopus)

12 Downloads (Pure)
Ageing as “early‐life inertia”: Disentangling life‐history trade‐offs along a lifetime of an individual
Carlsson, H., Ivimey‐Cook, E., Duxbury, E. M. L., Edden, N., Sales, K. & Maklakov, A. A., Oct 2021, In: Evolution Letters. 5, 5, p. 551-564 14 p.
Research output: Contribution to journal › Letter › peer-review

Open Access
File

10 Citations (Scopus)

17 Downloads (Pure)
Inbreeding reduces fitness of seed beetles under thermal stress
Ivimey-Cook, E., Bricout, S., Candela, V., Maklakov, A. A. & Berg, E. C., Sep 2021, In: Journal of Evolutionary Biology. 34, 9, p. 1386-1396 11 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File

2 Citations (Scopus)

14 Downloads (Pure)