Investigation of the processes determining mitochondrial fate in normal and malignant haematopoiesis

Rushworth, Stuart (Principal Investigator)
Bowles, Kristian (Co-Investigator)
Croft, Anya (Co-Investigator)
Croft, Anya (Technician)

Status	Finished
Effective start/end date	1/03/21 → 31/08/24

Funding

Medical Research Council: £457,755.24

Linking mitochondria, fatty acids and HSC expansion during infection: Implications for aging and metabolic diseases
Hampton, K., Polski-Delve, A., Hellmich, C. & Rushworth, S. A., Nov 2025, In: Stem Cells. 43, 11, sxaf053.
Research output: Contribution to journal › Article › peer-review

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1 Citation (Scopus)

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Single-cell gene and isoform expression analysis reveals signatures of ageing in haematopoietic stem and progenitor cells
Mincarelli, L., Uzun, V., Wright, D., Scoones, A., Rushworth, S. A., Haerty, W. & Macaulay, I. C., 24 May 2023, In: Communications Biology. 6, 558.
Research output: Contribution to journal › Article › peer-review

Open Access
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12 Citations (Scopus)

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Free fatty-acid transport via CD36 drives β-oxidation-mediated hematopoietic stem cell response to infection
Mistry, J. J., Hellmich, C., Moore, J. A., Jibril, A., Macaulay, I., Moreno-Gonzalez, M., Di Palma, F., Beraza, N., Bowles, K. M. & Rushworth, S. A., 8 Dec 2021, In: Nature Communications. 12, 1, 7130 .
Research output: Contribution to journal › Article › peer-review

Open Access
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92 Citations (Scopus)

25 Downloads (Pure)