Mechanistic studies of mitochondrial ferritin, a key player in iron mediated oxidative stress response and cellular iron metabolism

Le Brun, Nick (Principal Investigator)
Bradley, Justin (Co-Investigator)
Hemmings, Andrew (Co-Investigator)
Moore, Geoff (Co-Investigator)

Status	Finished
Effective start/end date	1/10/17 → 30/09/20

Funding

Biotechnology and Biological Sciences Research Council: £386,428.00

3 Article
1 Review article

Bacterial iron detoxification at the molecular level
Bradley, J. M., Svistunenko, D. A., Wilson, M. T., Hemmings, A. M., Moore, G. R. & Le Brun, N. E., 18 Dec 2020, In : The Journal of Biological Chemistry. 295, 51, p. 17602-17623 22 p.
Research output: Contribution to journal › Review article

Open Access
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2 Citations (Scopus)

19 Downloads (Pure)
Routes of iron entry into, and exit from, the catalytic ferroxidase sites of the prokaryotic ferritin SynFtn
Bradley, J., Pullin, J., Moore, G., Svistunenko, D. A., Hemmings, A. & Le Brun, N., 7 Feb 2020, In : Dalton Transactions. 49, 5, p. 1545-1554 10 p.
Research output: Contribution to journal › Article

Open Access
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3 Citations (Scopus)

22 Downloads (Pure)
Reaction of O₂ with a di-iron protein generates a mixed valent Fe²⁺/Fe³⁺ center and peroxide
Bradley, J. M., Svistunenko, D. A., Pullin, J., Hill, N., Stuart, R. K., Palenik, B., Wilson, M. T., Hemmings, A. M., Moore, G. R. & Le Brun, N. E., 5 Feb 2019, In : Proceedings of the National Academy of Sciences of the United States of America (PNAS). 116, 6, p. 2058-2067 10 p.
Research output: Contribution to journal › Article

Open Access
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12 Citations (Scopus)

10 Downloads (Pure)