MicroRNAs are key mediators of cartilage destruction in osteoarthritis: in vivo, in vitro and in silico studies

Clark, Ian (Principal Investigator)
Young, David (Principal Investigator)
Dalmay, Tamas (Co-Investigator)
Swingler, Tracey (Researcher)

Newcastle University

Status	Finished
Effective start/end date	1/01/17 → 31/12/22

Funding

Dunhill Medical Trust (The): £560,215.00

4 Article

HDAC6 regulates NF-κB signalling to control chondrocyte IL-1-induced MMP and inflammatory gene expression
Barter, M. J., Butcher, A., Wang, H., Tsompani, D., Galler, M., Rumsby, E. L., Culley, K. L., Clark, I. M. & Young, D. A., 22 Apr 2022, In: Scientific Reports. 12, 6640.
Research output: Contribution to journal › Article › peer-review

Open Access
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3 Downloads (Pure)
The microRNA-455 null mouse has memory deficit and increased anxiety, targeting key genes involved in Alzheimer’s disease
Swingler, T. E., Niu, L., Pontifex, M. G., Vauzour, D. & Clark, I. M., Jan 2022, In: International Journal of Molecular Sciences. 23, 1, 554.
Research output: Contribution to journal › Article › peer-review

Open Access
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2 Citations (Scopus)

17 Downloads (Pure)
TimiRGeN: R/Bioconductor package for time series microRNA-mRNA integration and analysis
Patel, K., Chandrasegaran, S., Clark, I. M., Proctor, C. J., Young, D. A. & Shanley, D. P., 15 Oct 2021, In: Bioinformatics. 37, 20, p. 3604–3609 6 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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3 Citations (Scopus)

10 Downloads (Pure)